Zobrazeno 1 - 8
of 8
pro vyhledávání: '"M. Desiree Watson"'
Autor:
Dean C. Luehrs, Sangram S. Sisodia, Alex E. Roher, Mark R. Emmerling, M. Desiree Watson, Daniel C. Brune, Tyler A. Kokjohn, Yu Min Kuo, Walter M. Kalback, Nicole Weiss, Matthias Staufenbiel, John Lopez
Publikováno v:
Biochemistry. 41:922-928
The amyloid (Abeta) peptides generated in Hsiao's APP Tg2576 transgenic (Tg) mice are physically and chemically distinct from those characteristic of Alzheimer's disease (AD). Transgenic mouse Abeta peptides were purified using sequential size-exclus
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1502(1):158-171
Complement proteins are integral components of amyloid plaques and cerebral vascular amyloid in Alzheimer brains. They can be found at the earliest stages of amyloid deposition and their activation coincides with the clinical expression of Alzheimer
Autor:
Walter Michael, Cuiman Cai, M. Desiree Watson, Lori M. Evans, Kevin K.W. Wang, Mark R. Emmerling, John L. Gilmore, Sheryl J. Hays, Lakshmi S. Narasimhan, Juan C. Jaen, Janet S. Plummer, Rathna Nath
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 9:815-820
A series of 2-sulfonyl-4H-3,1-benzoxazinones was prepared that inhibit C1r protease in vitro. Several compounds were found to be selective for C1r verses the related serine protease trypsin. Selected compounds demonstrated functional activity in a he
Publikováno v:
Amyloid. 4:147-156
Complement activation and its deposition on β-amyloid plaques in Alzheimer's Disease (AD) brains correlates with the development of AD dementia. Results from immunocytochemical studies suggest that the appearance of complement activation in AD brain
Autor:
Walter, Kalback, M Desiree, Watson, Tyler A, Kokjohn, Yu-Min, Kuo, Nicole, Weiss, Dean C, Luehrs, John, Lopez, Daniel, Brune, Sangram S, Sisodia, Matthias, Staufenbiel, Mark, Emmerling, Alex E, Roher
Publikováno v:
Biochemistry. 41(3)
The amyloid (Abeta) peptides generated in Hsiao's APP Tg2576 transgenic (Tg) mice are physically and chemically distinct from those characteristic of Alzheimer's disease (AD). Transgenic mouse Abeta peptides were purified using sequential size-exclus
Autor:
Tyler A. Kokjohn, Mark R. Emmerling, M. Desiree Watson, Amina S. Woods, Yu Min Kuo, Walter M. Kalback, Robert J. Cotter, Lucia I. Sue, Thomas G. Beach, Alex E. Roher
The levels of amyloid-beta40 (Abeta40) and Abeta42 peptides were quantified in temporalis muscles and brain of neuropathologically diagnosed Alzheimer disease (AD) and of nondemented individuals. This was achieved by using a novel analytical approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abfb29d133c9d0badb5789fb3b0eef4f
https://europepmc.org/articles/PMC1876838/
https://europepmc.org/articles/PMC1876838/
Autor:
Karl L. Brown, Taraneh Haske, M. Desiree Watson, Kathryn Spiegel, Charlotte Raby, Harry LeVine, Mark R. Emmerling, Lori M. Evans
Publikováno v:
Neurobiology of Aging. 21:90
Autor:
Katharyn Spiegel, Yu Min Kuo, Lori M. Evans, M. Desiree Watson, Thomas Kossmann, Philip F. Stahel, Maria Cristina Morganti-Kossmann, Pankaj D. Mehta, Mark R. Emmerling, Alex E. Roher, Charlotte Raby
Publikováno v:
Publons
The beta-amyloid peptides, A beta1-42 and A beta1-40, were quantified in ventricular CSF taken daily for up to 3 weeks from six individuals with severe traumatic brain injury (TBI). There was considerable interindividual variability in the levels of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73cb496eae986ff27fc25ab31eedc902
https://publons.com/publon/12753332/
https://publons.com/publon/12753332/