Zobrazeno 1 - 10
of 126
pro vyhledávání: '"M. Delorey"'
Autor:
Jiarui Ding, John J. Garber, Amiko Uchida, Ariel Lefkovith, Grace T. Carter, Praveen Vimalathas, Lauren Canha, Michael Dougan, Kyle Staller, Joseph Yarze, Toni M. Delorey, Orit Rozenblatt-Rosen, Orr Ashenberg, Daniel B. Graham, Jacques Deguine, Aviv Regev, Ramnik J. Xavier
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Coordinated cell interactions within the esophagus maintain homeostasis, and disruption can lead to eosinophilic esophagitis (EoE), a chronic inflammatory disease with poorly understood pathogenesis. We profile 421,312 individual cells from
Externí odkaz:
https://doaj.org/article/0442cca45bfc4b01b6f06f0a4b36b4f3
Autor:
Johannes F. Scheid, Basak Eraslan, Andrew Hudak, Eric M. Brown, Dallis Sergio, Toni M. Delorey, Devan Phillips, Ariel Lefkovith, Alison T. Jess, Lennard W. Duck, Charles O. Elson, Hera Vlamakis, Damian R. Plichta, Jacques Deguine, Ashwin N. Ananthakrishnan, Daniel B. Graham, Aviv Regev, Ramnik J. Xavier
Publikováno v:
Journal of Experimental Medicine. 220
Plasma cells (PCs) constitute a significant fraction of colonic mucosal cells and contribute to inflammatory infiltrates in ulcerative colitis (UC). While gut PCs secrete bacteria-targeting IgA antibodies, their role in UC pathogenesis is unknown. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51c9524b9243391c2f98718d67bd111c
https://doi.org/10.1084/jem.20220538
https://doi.org/10.1084/jem.20220538
Autor:
Yered Pita-Juarez, Dimitra Karagkouni, Nikolaos Kalavros, Johannes C. Melms, Sebastian Niezen, Toni M. Delorey, Adam L Essene, Olga R. Brook, Deepti Pant, Disha Skelton-Badlani, Pourya Naderi, Pinzhu Huang, Liuliu Pan, Tyler Hether, Tallulah S. Andrews, Carly G.K. Ziegler, Jason Reeves, Andriy Myloserdnyy, Rachel Chen, Andy Nam, Stefan Phelan, Yan Liang, Amit Dipak Amin, Jana Biermann, Hanina Hibshoosh, Molly Veregge, Zachary Kramer, Christopher Jacobs, Yusuf Yalcin, Devan Phillips, Michal Slyper, Ayshwarya Subramanian, Orr Ashenberg, Zohar Bloom-Ackermann, Victoria M. Tran, James Gomez, Alexander Sturm, Shuting Zhang, Stephen J. Fleming, Sarah Warren, Joseph Beechem, Deborah Hung, Mehrtash Babadi, Robert F. Padera, Sonya A. MacParland, Gary D. Bader, Nasser Imad, Isaac H. Solomon, Eric Miller, Stefan Riedel, Caroline B.M. Porter, Alexandra-Chloé Villani, Linus T.-Y. Tsai, Winston Hide, Gyongyi Szabo, Jonathan Hecht, Orit Rozenblatt-Rosen, Alex K. Shalek, Benjamin Izar, Aviv Regev, Yury Popov, Z. Gordon Jiang, Ioannis S. Vlachos
Publikováno v:
bioRxiv : the preprint server for biology.
The molecular underpinnings of organ dysfunction in acute COVID-19 and its potential long-term sequelae are under intense investigation. To shed light on these in the context of liver function, we performed single-nucleus RNA-seq and spatial transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd10833ef100648eb315ed90fe2285a
https://pubmed.ncbi.nlm.nih.gov/36324805
https://pubmed.ncbi.nlm.nih.gov/36324805
Autor:
Eran Hodis, Elena Torlai Triglia, John Y. H. Kwon, Tommaso Biancalani, Labib R. Zakka, Saurabh Parkar, Jan-Christian Hütter, Lorenzo Buffoni, Toni M. Delorey, Devan Phillips, Danielle Dionne, Lan T. Nguyen, Denis Schapiro, Zoltan Maliga, Connor A. Jacobson, Ayal Hendel, Orit Rozenblatt-Rosen, Martin C. Mihm, Levi A. Garraway, Aviv Regev
Publikováno v:
Science
Establishing causal relationships between genetic alterations of human cancers and specific phenotypes of malignancy remains a challenge. We sequentially introduced mutations into healthy human melanocytes in up to five genes spanning six commonly di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0b6b50554f24352b285b399233d3ad2
https://pubmed.ncbi.nlm.nih.gov/35482859
https://pubmed.ncbi.nlm.nih.gov/35482859
Autor:
Thomas K, Pedersen, Eric M, Brown, Damian R, Plichta, Joachim, Johansen, Shaina W, Twardus, Toni M, Delorey, Helena, Lau, Hera, Vlamakis, James J, Moon, Ramnik J, Xavier, Daniel B, Graham
Publikováno v:
Immunity. 55(10)
Reciprocal interactions between host T helper cells and gut microbiota enforce local immunological tolerance and modulate extra-intestinal immunity. However, our understanding of antigen-specific tolerance to the microbiome is limited. Here, we devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e0639d9d2fd22658da595c02f1da321
https://pubmed.ncbi.nlm.nih.gov/36223724
https://pubmed.ncbi.nlm.nih.gov/36223724
Autor:
Thomas K. Pedersen, Eric M. Brown, Damian R. Plichta, Joachim Johansen, Shaina W. Twardus, Toni M. Delorey, Helena Lau, Hera Vlamakis, James J. Moon, Ramnik J. Xavier, Daniel B. Graham
Publikováno v:
Immunity. 55:1909-1923.e6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7f6424a7ca0b4e0a148a9b8ac95a6aa
https://doi.org/10.1016/j.immuni.2022.08.016
https://doi.org/10.1016/j.immuni.2022.08.016
Autor:
Alexandra Schnell, Linglin Huang, Meromit Singer, Anvita Singaraju, Rocky M. Barilla, Brianna M.L. Regan, Alina Bollhagen, Pratiksha I. Thakore, Danielle Dionne, Toni M. Delorey, Mathias Pawlak, Gerd Meyer zu Horste, Orit Rozenblatt-Rosen, Rafael A. Irizarry, Aviv Regev, Vijay K. Kuchroo
Publikováno v:
Cell
While intestinal Th17 cells are critical for maintaining tissue homeostasis, recent studies have implicated their roles in the development of extra-intestinal autoimmune diseases including multiple sclerosis. However, the mechanisms by which tissue T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f10ce004e8bf90f96a70dd20b6c6a9
https://doi.org/10.1016/j.cell.2021.11.018
https://doi.org/10.1016/j.cell.2021.11.018
Autor:
Alexandra Schnell, Linglin Huang, Meromit Singer, Anvita Singaraju, Alina Bollhagen, Pratiksha I Thakore, Danielle Dionne, Toni M Delorey, Mathias Pawlak, Rafael Irizarry, Aviv Regev, Vijay K Kuchroo
Publikováno v:
The Journal of Immunology. 206:61.11-61.11
At homeostasis, most Th17 cells are found in the lamina propria of the intestine, where they contribute to tissue homeostasis by inhibiting microbiota from tissue invasion and promote barrier functions. Recent studies in humans and mice have implicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ee329723c2047d8034a6a4ee4592b68
https://doi.org/10.4049/jimmunol.206.supp.61.11
https://doi.org/10.4049/jimmunol.206.supp.61.11
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.