Zobrazeno 1 - 10
of 808
pro vyhledávání: '"M. Defelice"'
Autor:
Gardner, Michelle
Publikováno v:
Technical Communication, 2020 May 01. 67(2), 88-89.
Externí odkaz:
https://www.jstor.org/stable/27340138
Autor:
David A Van Valen, Takamasa Kudo, Keara M Lane, Derek N Macklin, Nicolas T Quach, Mialy M DeFelice, Inbal Maayan, Yu Tanouchi, Euan A Ashley, Markus W Covert
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 11, p e1005177 (2016)
Live-cell imaging has opened an exciting window into the role cellular heterogeneity plays in dynamic, living systems. A major critical challenge for this class of experiments is the problem of image segmentation, or determining which parts of a micr
Externí odkaz:
https://doaj.org/article/fbd13d77eb8040efa67c729bc11bb083
Autor:
Markus W. Covert, Miriam V. Gutschow, Helen R. Clark, Mialy M. DeFelice, Jacob J. Hughey, Inbal Maayan, Takamasa Kudo, Sergi Regot
Publikováno v:
Science signaling. 12(579)
Over the last decade, multiple studies have shown that signaling proteins activated in different temporal patterns—such as oscillatory, transient, and sustained—can result in distinct gene expression patterns or cell fates. However, the molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e40f11a2c8be52c7acbfb1e18359142
https://pubmed.ncbi.nlm.nih.gov/31040261
https://pubmed.ncbi.nlm.nih.gov/31040261
Autor:
Peter D. Karp, Inbal Maayan, Gwanggyu Sun, Sajia Akhter, Taryn E. Gillies, Daniel Weaver, Heejo Choi, Jerry H. Morrison, Samuel R. Bray, Ingrid M. Keseler, Morgan L. Paull, Ryan K. Spangler, Travis A. Ahn-Horst, Markus W. Covert, Nicholas A. Ruggero, Mialy M. DeFelice, John C. Mason, Javier Carrera, Derek N. Macklin, Keara Michelle Lane, Eran Agmon
Publikováno v:
Science. 369:eaav3751
The extensive heterogeneity of biological data poses challenges to analysis and interpretation. Construction of a large-scale mechanistic model of Escherichia coli enabled us to integrate and cross-evaluate a massive, heterogeneous dataset based on m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94b08b6985d35dcd7c31c99e05c62ffb
https://doi.org/10.1126/science.aav3751
https://doi.org/10.1126/science.aav3751
Autor:
Cole S. Purdy, Amber L. Alhadeff, Denise M. DeFelice, Karthikeyani Chellappa, Yajing Peng, Sarmistha Mukherjee, Jay L. Tomasiewicz, Matthew H. Wakai, Emma Meyer, Dudley W. Lamming, Mohammed I. Alotaibi, Georgios K. Paschos, J. Nicholas Betley, Isaac J. Perron, Amy Lin, Rebecca Yao, Luigi Puglielli, Joseph A. Baur, Sebastian I. Arriola Apelo, Jacqueline A. Brinkman, Mark Morrison, Kathryn A. Carbajal
Publikováno v:
Aging Cell
The mechanistic target of rapamycin (mTOR) is an evolutionarily conserved protein kinase that regulates growth and metabolism. mTOR is found in two protein complexes, mTORC1 and mTORC2, that have distinct components and substrates and are both inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::994cbabcf8d0e017a2f6531c34af4b8a
https://pubmed.ncbi.nlm.nih.gov/31373126
https://pubmed.ncbi.nlm.nih.gov/31373126
Autor:
Derek N, Macklin, Travis A, Ahn-Horst, Heejo, Choi, Nicholas A, Ruggero, Javier, Carrera, John C, Mason, Gwanggyu, Sun, Eran, Agmon, Mialy M, DeFelice, Inbal, Maayan, Keara, Lane, Ryan K, Spangler, Taryn E, Gillies, Morgan L, Paull, Sajia, Akhter, Samuel R, Bray, Daniel S, Weaver, Ingrid M, Keseler, Peter D, Karp, Jerry H, Morrison, Markus W, Covert
Publikováno v:
Science (New York, N.Y.). 369(6502)
The extensive heterogeneity of biological data poses challenges to analysis and interpretation. Construction of a large-scale mechanistic model of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9276b425197d6724fbd306f575e1a3a3
https://pubmed.ncbi.nlm.nih.gov/32994565
https://pubmed.ncbi.nlm.nih.gov/32994565
Autor:
Keara Michelle Lane, Derek N. Macklin, Ambrose J. Carr, Dana Pe'er, David Van Valen, Takamasa Kudo, Ariel Jaimovich, Mialy M. DeFelice, Markus W. Covert, Stéphane C. Boutet, Tobias Meyer
Signaling proteins display remarkable cell-to-cell heterogeneity in their dynamic responses to stimuli, but the consequences of this heterogeneity remain largely unknown. For instance, the contribution of the dynamics of the innate immune transcripti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13596dab7d50f897dbbaf1ec183ddd50
https://resolver.caltech.edu/CaltechAUTHORS:20180613-110240953
https://resolver.caltech.edu/CaltechAUTHORS:20180613-110240953
Autor:
Nicolas Quach, Markus W. Covert, Takamasa Kudo, David Van Valen, Inbal Maayan, Euan A. Ashley, Keara Michelle Lane, Yu Tanouchi, Derek N. Macklin, Mialy M. DeFelice
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 12, Iss 11, p e1005177 (2016)
PLoS Computational Biology, Vol 12, Iss 11, p e1005177 (2016)
Live-cell imaging has opened an exciting window into the role cellular heterogeneity plays in dynamic, living systems. A major critical challenge for this class of experiments is the problem of image segmentation, or determining which parts of a micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02940319140d5518d17fa351a799ce5d
https://pubmed.ncbi.nlm.nih.gov/27814364
https://pubmed.ncbi.nlm.nih.gov/27814364
P328 History of milk or soy protein intolerance in infancy in patients with eosinophilic esophagitis
Publikováno v:
Annals of Allergy, Asthma & Immunology. 119:S77-S78
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a16dbcf5f4848272c2b0a817b1264e9
https://doi.org/10.1016/j.anai.2017.08.219
https://doi.org/10.1016/j.anai.2017.08.219
Publikováno v:
Annals of Allergy, Asthma & Immunology. 121:S103
Introduction Children with Down syndrome (DS) are at risk for recurrent and severe respiratory tract infections, however lung abscesses are not commonly reported. Case Description The patient is a six-year-old male with DS, asthma, obstructive sleep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c98a7f6bb2e52d4fcc5ec10a69022ffd
https://doi.org/10.1016/j.anai.2018.09.339
https://doi.org/10.1016/j.anai.2018.09.339