Association between the Herpes Simplex Virus-1 DNA Polymerase and Uracil DNA Glycosylase

Autor: M. Defais, Ulrike Sattler, Federica Bogani, Wiriya Rutvisuttinunt, Virneliz Fernandez, Paul E. Boehmer, Ilsa Corredeira

Publikováno v: Journal of Biological Chemistry. 285:27664-27672

Herpes simplex virus-1 (HSV-1) is a large dsDNA virus that encodes its own DNA replication machinery and other enzymes involved in DNA transactions. We recently reported that the HSV-1 DNA polymerase catalytic subunit (UL30) exhibits apurinic/apyrimi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d5356879a46333165e5d5b9b5e38fdc
https://doi.org/10.1074/jbc.m110.131235

Equilibrium Binding of Single-stranded DNA to the Secondary DNA Binding Site of the Bacterial Recombinase RecA

Autor: Neil P. Johnson, M. Defais, Anne-Sophie Gourves

Publikováno v: Journal of Biological Chemistry. 276:9613-9619

The bacterial recombinase RecA forms a nucleoprotein filament in vitro with single-stranded DNA (ssDNA) at its primary DNA binding site, site I. This filament has a second site, site II, which binds ssDNA and double-stranded DNA. We have investigated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e70b579622e64b0050ae019d6cc78f9b
https://doi.org/10.1074/jbc.m004855200

Mammalian Rad51 protein: A RecA homologue with pleitropic functions

Autor: Stéphane Vispé, M. Defais

Publikováno v: Biochimie. 79:587-592

During the last years, homologues of E coli RecA have been cloned in numerous species including man. These Rad51 proteins share sequence as well as functional homologies with the bacterial protein. Human Rad51 (HsRad51) is able to catalyze strand exc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7d1e91e6825a4460bb963f20173cca7
https://doi.org/10.1016/s0300-9084(97)82007-x

Characterization of dinY, a new Escherichia coli DNA repair gene whose products are damage inducible even in a lexA(Def) background

Autor: C Petit, M. Defais, C Thompson, C Cayrol, P Kaiser, C Lesca

Publikováno v: Petit, P, Cayrol, C, Lesca, C, Kaiser, P, Thompson, C & Defais, M 1993, ' Characterisation of dinY, a new Escherichia coli DNA repair gene whose products are damage inducible even in a lexA(Def) background ', Journal of Bacteriology, vol. 175, pp. 642-646 .

Bacteriophage Mu dX(Ap lac) was used to isolate a mutation in an Escherichia coli lexA(Def) strain representing a previously undescribed gene (dinY) which does not seem to be under the direct control of LexA. The insertion created a dinY::lacZ fusion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b870a2c94b1f6f660f0284208fd4faa4
https://doi.org/10.1128/jb.175.3.642-646.1993

Characterization of the sensitivity to various genotoxic agents of the UVU1 CHO cell line, a double mutant from UV complementation group 1

Autor: Stéphane Vispé, M. Defais, Claire Lesca

Publikováno v: Biochimie. 79:261-263

The UVU1 CHO cell line, a double mutant of the excision repair complementation group 1 UV4 cell line was characterized by a higher UV sensitivity than its parent (Busch et al (1989) Mutagenesis 4, 349–354). We show here that this mutant is not affe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee6fd9d251950daf50b969b5cd7ab321
https://doi.org/10.1016/s0300-9084(97)83513-4