Zobrazeno 1 - 10
of 30
pro vyhledávání: '"M. Dahmani Fathallah"'
Autor:
Maryam Marzouq, Ali Nairouz, Noureddine Ben Khalaf, Sonia Bourguiba-Hachemi, Raed Quaddorah, Dana Ashoor, M. Dahmani Fathallah
Publikováno v:
BMC Research Notes, Vol 14, Iss 1, Pp 1-8 (2021)
Abstract Objective This study aimed to identify novel genetic variants in the CR2 extracellular domain of the epidermal growth factor receptor (EGFR) in healthy individuals and patients with six different types of adenocarcinoma, in Arabian peninsula
Externí odkaz:
https://doaj.org/article/ceff5d58f79e410ab9966bf011c5084c
Autor:
Noureddine Ben Khalaf, Wedad Al-Mashoor, Azhar Saeed, Wassim Raslan, Halla Bakheit, Ameera Abdulhadi, Ammar Marouani, Safa Taha, Moiz Bakhiet, M. Dahmani Fathallah
Publikováno v:
Biochemistry and Biophysics Reports, Vol 27, Iss , Pp 101100- (2021)
We previously reported Israa (immune-system-released activating agent), a novel gene nested in intron 6 of the mouse Zmiz1 gene. Zmiz1 is involved in several functions such as fertility and T cell development and its knockout leads to non-viable embr
Externí odkaz:
https://doaj.org/article/df0c09a5ac0442adb541266a47ce887d
Autor:
Dana Ashoor, Noureddine Ben Khalaf, Maryam Marzouq, Hamdi Jarjanazi, Sadok Chlif, M. Dahmani Fathallah
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
SARS-CoV-2 infectivity is largely determined by the virus Spike protein binding to the ACE2 receptor. Meanwhile, marked infection rate differences were reported between populations and individuals. To understand the disease dynamic, we developed a co
Externí odkaz:
https://doaj.org/article/4217f2d18bbd4a1095fb889f9153bbe1
Publikováno v:
JMIR Bioinformatics and Biotechnology, Vol 5, p e58018 (2024)
BackgroundThe rapid evolution of SARS-CoV-2 imposed a huge challenge on disease control. Immune evasion caused by genetic variations of the SARS-CoV-2 spike protein’s immunogenic epitopes affects the efficiency of monoclonal antibody–based therap
Externí odkaz:
https://doaj.org/article/527f47bac9d546f485d53e289e0e1c46
Autor:
Khaled Trabelsi, Noureddin Ben Khalaf, Ahmed R. Ramadan, Amany Elsharkawy, Dana Ashoor, Sadok Chlif, Thouraya Boussoffara, Melika Ben-Ahmed, Mukesh Kumar, M-Dahmani Fathallah
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Efficient precision vaccines against several highly pathogenic zoonotic viruses are currently lacking. Proteolytic activation is instrumental for a number of these viruses to gain host-cell entry and develop infectivity. For SARS-CoV-2, this process
Externí odkaz:
https://doaj.org/article/1d57304960104963ac716a935fd8b201
Autor:
Dana Ashoor, Maryam Marzouq, Khaled Trabelsi, Sadok Chlif, Nasser Abotalib, Noureddine Ben Khalaf, Ahmed R. Ramadan, M-Dahmani Fathallah
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
In this study, we evaluated the use of a predictive computational approach for SARS-CoV-2 genetic variations analysis in improving the current variant labeling system. First, we reviewed the basis of the system developed by the World Health Organizat
Externí odkaz:
https://doaj.org/article/3627a504ac0e47fe8843c24bba2ec17b
Immune escape caused by genetic variations of SARS-CoV-2 S protein immunogenic epitopes affects the efficiency of monoclonal antibody-based therapy of COVID-19. Therefore, predicting the effects of these variations on immune escape is important to ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7305753b3e95605add6d288f7b782da
https://doi.org/10.21203/rs.3.rs-2696333/v1
https://doi.org/10.21203/rs.3.rs-2696333/v1
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149612 (2016)
The interplay between the nervous and immune systems is gradually being unraveled. We previously reported in the mouse the novel soluble immune system factor ISRAA, whose activation in the spleen is central nervous system-dependent. We also showed th
Externí odkaz:
https://doaj.org/article/a8738e7014c54540b57754042ebf48cb
Autor:
Maryam Marzouq, Amal Alshammary, Sonia Bourguiba-Hachemi, Waseem Raslan, Dana Ashoor, M. Dahmani Fathallah
Background: The epidermal growth factor receptor (EGFR) was the first molecular marker to be targeted successfully in monoclonal antibodies-based cancer immunotherapy. The human EGFR displays two common natural genetic variants (R521K) located in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84ca7ab68f2bc96fadf6b5b5a6f6f5a3
https://doi.org/10.21203/rs.3.rs-1132248/v1
https://doi.org/10.21203/rs.3.rs-1132248/v1
Autor:
M. Dahmani Fathallah, Dana Ashoor, Sadok Chlif, Maryam Marzouq, Noureddine Ben Khalaf, Hamdi Al Jarjanazi
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
SARS-CoV-2 infectivity is largely determined by the virus Spike protein binding to the ACE2 receptor. Meanwhile, marked infection rate differences were reported between populations and individuals. To understand the disease dynamic, we developed a co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e7d804826b89ddc48aa8a2c7ea2ffe
http://europepmc.org/articles/PMC8381355
http://europepmc.org/articles/PMC8381355