Výsledky vyhledávání - "M. D. Muenter"

L-DOPA biotransformation: correlations of dosage, erythrocyte catechol O-methyltransferase and platelet SULT1A3 activities with metabolic pathways in Parkinsonian patients

Autor: M. D. Muenter, Gertrude M. Tyce, K. P. Offord, M. K. Dousa, P. A. Decker, Richard M. Weinshilboum

Publikováno v: Journal of Neural Transmission. 110:899-910

The objectives of this study were to determine (1) the effects of dose and drug absorption on pathways of biotransformation of L-DOPA in Parkinsonian patients treated with Sinemet, and (2) the extent to which genetically-determined variations in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e14b81cacaa6a3abbe6d53f5fd853965
https://doi.org/10.1007/s00702-003-0001-2

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Effect of MK-458 (HPMC) in Parkinsonʼs Disease Previously Untreated With Dopaminergic Drugs. A Double-Blind, Placebo-Controlled Multicenter Study

Autor: William C. Koller, C. Singer, J. E. Ahlskog, C. Liss, W. J. Weiner, G. Cyhan, P. A. LeWitt, S. Stellar, Nausieda Pa, S. Ahrens, H. Moses, J. M. Cedarbaum, L. McLean, Christopher G. Goetz, G. Block, M. D. Muenter, S. Reich, Juan Sanchez-Ramos

Publikováno v: Scopus-Elsevier

Ninety-four patients with early Parkinson's disease were investigated in a double-blind, placebo-controlled evaluation of MK-458 [hydroxypropyl methylcellulose/lactose matrix (HPMC)], a sustained release formulation of a novel naphthoxazine compound

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9cbd3c298bd3790e44310626678732d
https://doi.org/10.1097/00002826-199108000-00004

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Motor unit changes in sporadic idiopathic Parkinson's disease

Autor: J N, Caviness, B E, Smith, J C, Stevens, C H, Adler, R J, Caselli, C A, Reiners, J G, Hentz, M D, Muenter

Publikováno v: Movement disorders : official journal of the Movement Disorder Society. 15(2)

We studied motor unit changes in 20 patients with Parkinson's disease (PD) and 20 age-matched control subjects to look for evidence of motorneuron degeneration in sporadic idiopathic PD. Patients and control subjects were screened by clinical criteri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::509cfb6578bd51698e15ed809608348e
https://pubmed.ncbi.nlm.nih.gov/10752572

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Electrophysiological observations in hereditary parkinsonism-dementia with Lewy body pathology

Autor: J N, Caviness, K, Gwinn-Hardy, C H, Adler, M D, Muenter

Publikováno v: Movement disorders : official journal of the Movement Disorder Society. 15(1)

We studied the only two living affected individuals who are part of a previously reported kindred that expresses a hereditary parkinsonism-dementia syndrome with Lewy body pathology. The electrophysiological characteristics of the hyperkinetic moveme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7a105a4ce5be4b55b4b25b42107ff8a1
https://pubmed.ncbi.nlm.nih.gov/10634254

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Cortical myoclonus in levodopa-responsive parkinsonism

Autor: J N, Caviness, C H, Adler, S, Newman, R J, Caselli, M D, Muenter

Publikováno v: Movement disorders : official journal of the Movement Disorder Society. 13(3)

We observed myoclonic movements of the fingers and wrists in two patients with a levodopa-responsive parkinsonian syndrome most consistent with Parkinson's disease. These patients were studied with electrophysiological techniques. Brief (50 ms) myocl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2cd86897d661b09d531a2dc1c741a16e
https://pubmed.ncbi.nlm.nih.gov/9613750

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MAO and L-DOPA treatment of Parkinson’s disease

Autor: M. K. Dousa, Gertrude M. Tyce, M. D. Muenter

Publikováno v: Neurotransmitter Actions and Interactions ISBN: 9783211821428

The aim of this study was to determine whether there were differences in the oxidative deamination of dopamine in patients with Parkinson’s disease who demonstrated a long-duration response (LDR) to treatment with dopa and carbidopa and in patients

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5d31a97fcc38a75436742b71d15fcaf7
https://doi.org/10.1007/978-3-7091-9050-0_22

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MAO and L-dopa treatment of Parkinson's disease

Autor: G M, Tyce, M K, Dousa, M D, Muenter

Publikováno v: Journal of neural transmission. Supplementum. 29

The aim of this study was to determine whether there were differences in the oxidative deamination of dopamine in patients with Parkinson's disease who demonstrated a long-duration response (LDR) to treatment with dopa and carbidopa and in patients w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::381c976a392fdf6187690dfde0e11b70
https://pubmed.ncbi.nlm.nih.gov/2358803

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