Zobrazeno 1 - 10
of 10
pro vyhledávání: '"M. D. Hogan"'
Autor:
F L, Cavender, W H, Steinhagen, C E, Ulrich, W M, Busey, B Y, Cockrell, J K, Haseman, M D, Hogan, R T, Drew
Publikováno v:
Journal of Toxicology and Environmental Health. 3:521-533
Ozone and the oxides of sulfur are common environmental pollutants. The acute pulmonary lesions caused by ozone and sulfuric acid mist in rats and guinea pigs have been characterized. Rats are not affected by sulfuric acid mist in concentrations up t
Publikováno v:
American Journal of Public Health and the Nations Health. 57:452-459
Autor:
M D Hogan
Publikováno v:
Environmental Health Perspectives
Laboratory-generated animal bioassay data often serve as the basis for estimating potential human cancer risk. However, there is no single procedure that has been universally accepted as the method of choice for extrapolating experimentally observed
Publikováno v:
Biometrics. 42(1)
The fitting of dose-response models to teratology data involving littermates in order to generate estimates of teratogenic risk is receiving increasing attention as a potential alternative to the "safety-factor" approach to risk estimation. In this p
Publikováno v:
American journal of epidemiology. 108(1)
K.J. Rothman has explored in some detail the issue of assessing the potential presence of synergism (or antagonism) in data generated from either a cohort or a case-control study. Arguing that the "natural" scale for quantifying the joint effects of
Publikováno v:
Journal of environmental pathology and toxicology. 2(3)
This paper discusses some of the statistical and biological problems that are likely to be encountered when an indirect or ecological approach is used to assess the possible public health impact of general population exposures to environmental agents
Publikováno v:
Journal of environmental pathology and toxicology. 2(2)
Blood lead and hypertension are associated in adults. We attempted to duplicate this finding in a presumably more susceptible group of children. Small but statistically significant negative corelations were found between blood pressure and lead level
Publikováno v:
JAMA. 232(4)
The use of methotrexate in psoriasis has recently been questioned because of possible carcinogenic potential. Two hundred twenty-four patients began methotrexate therapy during 1960 to 1965 at the Cleveland Clinic and at Duke University Medical Cente
Publikováno v:
Science (New York, N.Y.). 168(3933)
The herbicide 2,4,5-trichlorophenoxyacetic acid is teratogenic and fetocidal in two strains of mice when administered either subcutaneously or orally and in one strain of rats when administered orally. The incidences of both cystic kidney and cleft p