Zobrazeno 1 - 10
of 19
pro vyhledávání: '"M. D. Chaplin"'
Publikováno v:
Proceedings of the Western Pharmacology Society. 40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fadaf20838a70bcdb64b1680c4e3f17f
https://pubmed.ncbi.nlm.nih.gov/9436213
https://pubmed.ncbi.nlm.nih.gov/9436213
Publikováno v:
Experimental Biology and Medicine. 143:667-671
SummaryIntravenous administration of high doses of aspirin, phenylbutazone or naproxen to rats which had just regained the righting reflex from an anesthetic dose of thiopental caused them to again lose their righting reflex. Naproxen was also shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3026a0fe6192661170ff49d18ce79a4
https://doi.org/10.3181/00379727-143-37387
https://doi.org/10.3181/00379727-143-37387
Autor:
N I, Chu, B A, Amos, L, Tökés, M L, Maddox, S B, Matin, K M, Hama, J W, Patterson, P J, Wagner, J P, Bell, M D, Chaplin
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 7(2)
Flunisolide (6 alpha-fluoro-11 beta, 16 alpha, 17 alpha, 21-tetrahydroxypregna-1,4-diene-3,20-dione 16,17-acetonide) administered as a single iv or oral dose to rats, mice, dogs, rhesus monkeys, and cynomolgus monkeys had a plasma t 1/2 of 1-3.5 hr a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3aeb0ff7fa8b7349f5f8d6e070535af9
https://pubmed.ncbi.nlm.nih.gov/38078
https://pubmed.ncbi.nlm.nih.gov/38078
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 218(1)
Flunisolide (6 alpha-fluoro-11 beta, 16 alpha, 17 alpha, 21-tetrahydroxypregna-1,4-diene-3,20-dione-16,17-acetonide) was converted to 6 beta,- 11 beta, 16 alpha, 21-pentahydroxypregna-1,4-diene-3,20-dione-16,17-acetonide (6 beta-OH metabolite) by mou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b562ba52fda543afc273bd84efd2f11b
https://pubmed.ncbi.nlm.nih.gov/7241375
https://pubmed.ncbi.nlm.nih.gov/7241375
Publikováno v:
LHRH and Its Analogs ISBN: 9789401089630
The delivery of polypeptide and protein drugs by a convenient and effective method is a major challenge in the development of these compounds as therapeutic agents. Due to degradation and/or lack of absorption in the gastrointestinal tract, large, un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55a63046129f0cecb73b2412c2ea96d8
https://doi.org/10.1007/978-94-009-5588-2_33
https://doi.org/10.1007/978-94-009-5588-2_33
Publikováno v:
Proceedings of the Western Pharmacology Society. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::11b0a71320d62fa3c1867dbe81ae1d94
https://pubmed.ncbi.nlm.nih.gov/1182041
https://pubmed.ncbi.nlm.nih.gov/1182041
Autor:
R L, Chan, M D, Chaplin
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 13(5)
Nafarelin acetate (less than Glu-His-Trp-Ser-Tyr-3-(2-naphthyl)-D-Ala-Leu-Arg-Pro-Gly-NH2) is a potent agonistic analogue of luteinizing hormone-releasing hormone. After a single iv administration of nafarelin acetate (with 14C label at C-3 of 3-(2-n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2230fdb0f01ad6bfd7245a58d60d2164
https://pubmed.ncbi.nlm.nih.gov/2865104
https://pubmed.ncbi.nlm.nih.gov/2865104
Publikováno v:
Proceedings of the Western Pharmacology Society. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::391c0d3361dd4d5043c4637c1197ccd2
https://pubmed.ncbi.nlm.nih.gov/7122521
https://pubmed.ncbi.nlm.nih.gov/7122521
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 9(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::93d2892c2b0b225a3e3528adc3297582
https://pubmed.ncbi.nlm.nih.gov/6117452
https://pubmed.ncbi.nlm.nih.gov/6117452
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 15(4)
The absorption, distribution, excretion, and metabolism of 14C-nafimidone, a novel anticonvulsant, have been studied in rats. Nafimidone was completely absorbed following single oral doses of 10 and 100 mg/kg. After both iv and oral administration, n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::98663953f88d5b1c8c72c088a8a7ee3d
https://pubmed.ncbi.nlm.nih.gov/2888632
https://pubmed.ncbi.nlm.nih.gov/2888632