Zobrazeno 1 - 10
of 215
pro vyhledávání: '"M. D'Costa"'
Autor:
Farah Nasser, Avery Gaudreau, Shareefah Lubega, Arvin Zaker, Xuhua Xia, Arvind S. Mer, Vanessa M. D’Costa
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
The multi-drug resistant pathogen Acinetobacter baumannii has gained global attention as an important clinical challenge. Owing to its ability to survive on surfaces, its capacity for horizontal gene transfer, and its resistance to front-line antibio
Externí odkaz:
https://doaj.org/article/4c27afe752ec4b54939f2ab96f6245fd
Autor:
Karan Mediratta, Sara El-Sahli, Marie Marotel, Muhammad Z. Awan, Melanie Kirkby, Ammar Salkini, Reem Kurdieh, Salman Abdisalam, Amit Shrestha, Chiara Di Censo, Andrew Sulaiman, Sarah McGarry, Jessie R. Lavoie, Zhen Liu, Seung-Hwan Lee, Xuguang Li, Giuseppe Sciumè, Vanessa M. D’Costa, Michele Ardolino, Lisheng Wang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionChemotherapy remains the mainstay treatment for triple-negative breast cancer (TNBC) due to the lack of specific targets. Given a modest response of immune checkpoint inhibitors in TNBC patients, improving immunotherapy is an urgent and c
Externí odkaz:
https://doaj.org/article/10213cd0c20d41adb4e2783bba54bf80
Autor:
Kirsten C. Boddy, Hongxian Zhu, Vanessa M. D’Costa, Caishuang Xu, Ksenia Beyrakhova, Miroslaw Cygler, Sergio Grinstein, Etienne Coyaud, Estelle M. N. Laurent, Jonathan St-Germain, Brian Raught, John H. Brumell
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Salmonella secretes the effector protein SopD into the host cell cytoplasm, leading to scission of the plasma membrane through unclear mechanisms. Here, Boddy et al. show that SopD binds to and inhibits the small GTPase Rab10, thus promoting removal
Externí odkaz:
https://doaj.org/article/c637d11be435406898ecf3fc34ead099
Autor:
Sara El-Sahli, Khang Hua, Andrew Sulaiman, Jason Chambers, Li Li, Eliya Farah, Sarah McGarry, Dan Liu, Peiyong Zheng, Seung-Hwan Lee, Jiefeng Cui, Marc Ekker, Marceline Côté, Tommy Alain, Xuguang Li, Vanessa M. D’Costa, Lisheng Wang, Suresh Gadde
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-10 (2021)
Abstract Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, accounting for the majority of breast cancer-related death. Due to the lack of specific therapeutic targets, chemotherapeutic agents (e.g., paclitaxel) rem
Externí odkaz:
https://doaj.org/article/01bd15f375e049938f736c0619b78c47
Autor:
Ninadh M. D’Costa, Matthew R. Lowerison, Peter A. Raven, Zheng Tan, Morgan E. Roberts, Raunak Shrestha, Matthew W. Urban, Cesar U. Monjaras-Avila, Htoo Zarni Oo, Antonio Hurtado-Coll, Claudia Chavez-Munoz, Alan I. So
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-16 (2020)
Abstract Background Renal cell carcinoma (RCC) is a highly vascular tumor and patients with low risk metastatic RCC of clear-cell histological sub-type (mccRCC) are treated with tyrosine-kinase inhibitors (TKIs), sunitinib, as the first-line of treat
Externí odkaz:
https://doaj.org/article/2252c7e81c1e43debda08663145ad30a
Akademický článek
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Autor:
Vanessa M. D’Costa, Virginie Braun, Marija Landekic, Rong Shi, Ariane Proteau, Laura McDonald, Miroslaw Cygler, Sergio Grinstein, John H. Brumell
Publikováno v:
Cell Reports, Vol 12, Iss 9, Pp 1508-1518 (2015)
Intracellular bacterial pathogens of a diverse nature share the ability to evade host immunity by impairing trafficking of endocytic cargo to lysosomes for degradation, a process that is poorly understood. Here, we show that the Salmonella enterica t
Externí odkaz:
https://doaj.org/article/17bde13531c845b49f53f66a85fa1101
Publikováno v:
Journal of Digestive Endoscopy, Vol 05, Iss 04, Pp 164-167 (2014)
Percutaneous endoscopic gastrostomy (PEG) is a standard procedure for enteral feeding tube placement in the stomach for patients with nonobstructive dysphagia. Major and minor complications have been described in early and delayed phase. We describe
Externí odkaz:
https://doaj.org/article/95fda4a44fb245eeb56eafd949854ae2
Akademický článek
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Autor:
Susan M. D'Costa, Michael DiBiasio-White, Franz Gerner, Jim Warren, Jessica Tate, Michael Delahaye
Publikováno v:
Cell and Gene Therapy Insights. 6:1739-1754