Zobrazeno 1 - 10
of 122
pro vyhledávání: '"M. Czejka"'
Publikováno v:
Case Reports in Oncology, Vol 6, Iss 3, Pp 602-608 (2013)
Erlotinib is an oral epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor approved for the treatment of non-small cell lung cancer and when combined with gemcitabine for pancreatic cancer. Dose reduction of erlotinib in patients with sev
Externí odkaz:
https://doaj.org/article/7edb3d9f57d04eeebcca0ee2442f90af
Publikováno v:
Journal of Clinical Pharmacy and Therapeutics, 42(4), 446-453. Blackwell Publishing Ltd
What is known and objectiveMedication errors are a significant cause of morbidity and mortality especially with antineoplastic drugs, owing to their narrow therapeutic index. Gravimetric workflow software systems have the potential to reduce volumetr
Akademický článek
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Publikováno v:
Anticancer research. 31(10)
Biotransformation of irinotecan (CPT-11) into its pharmacologic active metabolite SN-38 was investigated in patients treated for advanced colorectal cancer. A dose of 180 mg/m(2) CPT-11 was administered to 6 patients by 60 min hepatic intra-arterial
Publikováno v:
Anticancer research. 20(5C)
Cytoprotection of healthy cells represents a new approach in cancer chemotherapy, but a pharmacokinetic drug interaction between the cytostatic and the cytoprotectant is undesired.The purpose was to evaluate the clinical pharmacokinetics (PHK) of pac
Publikováno v:
Die Pharmazie. 51(11)
The in vitro binding rate of epirubicin (EPR) to different plasma proteins, control serum, red blood cells and whole blood was investigated without and with the cytoprotective agent amifostine. The binding rate of EPR to plasma proteins fractions and
Publikováno v:
Die Pharmazie. 50(6)
The concentration-time profile of 5-fluorouracil (5FU) in serum of patients during continuous infusion of 5FU for five days was investigated. The coadministration of each of 5 million units interferon-alpha-2b (IFN) on day 2 and 4 of the infusion cau
Publikováno v:
Arzneimittel-Forschung. 45(2)
The influence of interferon-alpha-2b (CAS 99210-65-8, IFN) on the pharmacokinetics of epirubicin (CAS 56420-45-2, EPR) was investigated in 10 patients (4 male, 6 female). EPR was injected as an i.v. bolus over 2 min in a dose of 60 mg/m2 IFN was pre-
Publikováno v:
Investigative ophthalmologyvisual science. 33(5)
Forty six patients received a topical application of a 0.3% norfloxacin (Zoroxin; MSD, Austria) solution into the lower fornix at different time intervals and frequencies before undergoing planned extracapsular cataract extraction. Aqueous humor was
Autor:
M, Czejka, J, Schüller
Publikováno v:
Archiv der Pharmazie. 325(2)
The binding of 5-fluorouracil (1) to erythrocytes and to serum proteins under in vitro conditions was investigated. The binding rate of 1 to erythrocytes is dose-independent and amounts from 16.8 to 31.7% (concentration range 1 to 20 micrograms/ml).