Zobrazeno 1 - 10
of 35
pro vyhledávání: '"M. Cukierski"'
Autor:
Alice F. Tarantal, Calvin C. Willhite, M. Cukierski, Steven A. Book, Andrew G Hendrickx, Christopher J. Miller, Bill L. Lasley, Christopher J. Murphy
Publikováno v:
Fundamental and Applied Toxicology. 16:147-160
Forty pregnant long-tailed macaques were dosed via nasogastric intubation with 0, 25, 150, or 300 μg/kg of l -selenomethionine (Se) daily during organogenesis [Gestational Day (GD) 20–50]. Clinical examination of the dams, maternal body weights, s
Autor:
M. Cukierski, Wai Nang Choy, Stanley T. Omaye, Calvin C. Willhite, Wayne Chris Hawkes, Douglas N. Cox
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 30(11)
20 adult female macaques (Macaca fascicularis) were given oral doses of L-selenomethionine (L-SeMet) equivalent to 0, 25, 150, 300 and 600 micrograms selenium (Se)/kg body weight, and plasma, erythrocyte, hair, faecal and urine Se concentrations were
30-day oral toxicity study of -selenomethionine in female long-tailed macaques (Macaca fascicularis)
Autor:
Steven A. Book, Douglas N. Cox, Calvin C. Willhite, Andrew G Hendrickx, Tammy A. Hendrie, M. Cukierski, Bill L. Lasley
Publikováno v:
Fundamental and Applied Toxicology. 13:26-39
Twenty female long-tailed macaques received nasogastric intubation of 0-600 micrograms/kg-day L-selenomethionine for up to 30 consecutive days. Selenium ingestion was well tolerated at all dose levels until the second to third week of the study at wh
Autor:
J. D. Rodgers, Andrew G Hendrickx, Thomas G. Nyland, Alice F. Tarantal, Mark A. Cukierski, M. Cukierski, C. P. Peter, A. G. Zacchei, Richard T. Robertson, S. Prahalada, David L. Hess
Publikováno v:
Teratology. 39:39-52
Norfloxacin, a new orally active antibiotic, was investigated in cynomolgus monkeys for potential developmental toxicity. Fifty-seven monkeys were administered a control vehicle or norfloxacin by nasogastric gavage during the major period of organoge
Publikováno v:
Acta anatomica. 127(3)
Placentation in the green monkey (Cercopithecus aethiops) from gestational ages of 18-30 days was studied by light and electron microscopy. The placentae show many features in common with that of the rhesus monkey and other related macaques. Implanta
Publikováno v:
Teratology. 32(3)
A single dose of MPA (Depo-Provera; Upjohn Co., Kalamazoo, Michigan) was administered intramuscularly to 12 time-mated pregnant cynomolgus monkeys on day 27 (+/- 2) of gestation at 25 mg/kg or at 100 mg/kg. Maternal blood samples were collected immed
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 8(1)
This study examined the pharmacokinetics and potential teratogenicity of the nonsteroidal antiinflammatory drug, difflunisal, in cynomolgus monkeys. Pregnant cynomolgus monkeys were administered 0.5% methyl cellulose, 20 mg/kg/day diflunisal, or 80 m
Publikováno v:
Teratology. 32(2)
Cynomolgus monkeys, rhesus monkeys and baboons were administered 10 to 40 times the human dose equivalent of Bendectin throughout the major period of organogenesis (22(+/-3)-50 days of gestation). In animals examined prenatally (100 +/- 2 days gestat
Publikováno v:
Journal of experimental pathology. 4(4)
Interferon inhibits the normal replication of C-type virus particles grown in vitro. The ability of interferon to produce a similar effect in vivo was tested in rhesus monkey placentas which are known to contain C-type virus particles. Samples of pla
Autor:
Heinz Nau, J. M. Rowland, Pamela E. Binkerd, Mark A. Cukierski, M. Cukierski, Andrew G Hendrickx, Jeffrey R. Rowland
Publikováno v:
Teratology. 38(4)
This study was undertaken to assess the developmental toxicity and drug distributional and metabolic characteristics of prenatal valproic acid (VPA) exposure in rhesus monkeys. Oral administration of 20-600 mg/kg/day VPA (approximately 1-15 X human t