Výsledky vyhledávání - "M. Cruz Miraglia"

Akademický článek

Brucella abortus-Stimulated Platelets Activate Brain Microvascular Endothelial Cells Increasing Cell Transmigration through the Erk1/2 Pathway

Autor: Ana María Rodríguez, Aldana Trotta, Agustina P. Melnyczajko, M. Cruz Miraglia, Kwang Sik Kim, M. Victoria Delpino, Paula Barrionuevo, Guillermo Hernán Giambartolomei

Publikováno v: Pathogens, Vol 9, Iss 9, p 708 (2020)

Central nervous system invasion by bacteria of the genus Brucella results in an inflammatory disorder called neurobrucellosis. A common feature associated with this pathology is blood–brain barrier (BBB) activation. However, the underlying mechanis

Externí odkaz: https://doaj.org/article/58d0c4cbaad640818b549a9ae6df808d

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Brucella abortus-Stimulated Platelets Activate Brain Microvascular Endothelial Cells Increasing Cell Transmigration through the Erk1/2 Pathway

Autor: M. Victoria Delpino, Kwang Sik Kim, M. Cruz Miraglia, Agustina P. Melnyczajko, Aldana Trotta, Ana M. Rodríguez, Paula Barrionuevo, Guillermo H. Giambartolomei

Publikováno v: Pathogens, Vol 9, Iss 708, p 708 (2020)
Pathogens
Volume 9
Issue 9
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Central nervous system invasion by bacteria of the genus Brucella results in an inflammatory disorder called neurobrucellosis. A common feature associated with this pathology is blood&ndash
brain barrier (BBB) activation. However, the underlying

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0937e1616ffb708f297e6531e811c61a
https://www.mdpi.com/2076-0817/9/9/708

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Brucella abortus-activated microglia induce neuronal death through primary phagocytosis

Autor: Paula Barrionuevo, Guillermo H. Giambartolomei, M. Victoria Delpino, Ana M. Rodríguez, Vida A. Dennis, Miriam M. Costa Franco, M. Cruz Miraglia, Sergio C. Oliveira

Publikováno v: Glia. 65:1137-1151

Inflammation has long been implicated as a contributor to pathogenesis in neurobrucellosis. Many of the associated neurocognitive symptoms of neurobrucellosis may be the result of neuronal dysfunction resulting from the inflammatory response induced

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af9cf69804c1b20381c590377bdc5512
https://doi.org/10.1002/glia.23149

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Systemic antibodies administered by passive immunization prevent generalization of the infection by foot-and-mouth disease virus in cattle after oronasal challenge

Autor: Andrea Ayude, M. Cruz Miraglia, Juan Manuel Schammas, Sebastián Di Giacomo, Florencia Barrionuevo, Manuel V. Borca, Danilo Bucafusco, M. Pérez-Filgueira, Alejandra Victoria Capozzo

The role of passively transferred sera in the protection against aerogenous foot-and-mouth disease (FMD) virus infection in cattle was evaluated using vaccine-induced immune serum preparations obtained at 7 and 26 days post-vaccination (dpv). We show

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb6252eb1eb7f1a4ae0a49decd422c08
https://www.sciencedirect.com/science/article/pii/S0042682218300552

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Brucella abortus induces apoptosis of human T lymphocytes

Autor: Paula Barrionuevo, Romina Scian, Juliana Cassataro, Lis N. Velásquez, Lorena M. Coria, M. Cruz Miraglia, Andrés E. Ibañez, Guillermo H. Giambartolomei, M. Victoria Delpino

Publikováno v: Microbes and Infection. 14:639-650

Immune evasion is essential for Brucella abortus to survive in the face of robust adaptive CD4+ T cell response. We have previously demonstrated that B. abortus can indirectly inhibit CD4+ T cells by down-regulating MHC-II expression and antigen pres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8972135f9ab81edc7598edd1c6753398
https://doi.org/10.1016/j.micinf.2012.02.004

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Macrophage-elicited osteoclastogenesis in response to Brucella abortus infection requires TLR2/MyD88-dependent TNF-α production

Autor: Paula Barrionuevo, Pablo C. Baldi, Romina Scian, Carlos A. Fossati, M. Victoria Delpino, Guillermo H. Giambartolomei, Silvia Di Genaro, Sergio C. Oliveira, M. Cruz Miraglia, Gilson Costa Macedo

Publikováno v: Journal of leukocyte biology. 91(2)

Osteoarticular complications are common in human brucellosis, but the pathogenic mechanisms involved are largely unknown. In this manuscript, we described an immune mechanism for inflammatory bone loss in response to infection by Brucella abortus. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dc218310369ba98d4cf60ed032c5510
https://pubmed.ncbi.nlm.nih.gov/22075930

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Brucella abortus induces TNF-α-dependent astroglial MMP-9 secretion through mitogen-activated protein kinases

Autor: Paula Barrionuevo, Clara García Samartino, Pablo C. Baldi, Romina Scian, Lis N. Velásquez, Andrés E. Ibañez, Juliana Cassataro, Lorena M. Coria, M. Victoria Delpino, M. Cruz Miraglia, Ana M. Rodríguez, Guillermo H. Giambartolomei

Publikováno v: Journal of Neuroinflammation

Background Central nervous system (CNS) invasion by bacteria of the genus Brucella results in an inflammatory disorder called neurobrucellosis. We have recently demonstrated that B. abortus infects microglia and astrocytes, eliciting the production o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43ac08de6551989417d3c262d7cc5763
http://europepmc.org/articles/PMC3637408

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