Zobrazeno 1 - 5
of 5
pro vyhledávání: '"M. Cristina Moroni"'
Publikováno v:
Current Opinion in Genetics & Development. 12:60-66
Loss of function of both the p53 pathway and the retinoblastoma protein (pRB) pathway plays a significant role in the development of most human cancers. Loss of pRB results in deregulated cell proliferation and apoptosis, whereas loss of p53 desensit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86c1b666562cfe66e48b235d1ca9f550
https://doi.org/10.1016/s0959-437x(01)00265-9
https://doi.org/10.1016/s0959-437x(01)00265-9
Autor:
Kristian Helin, Peter Cartwright, Claire Attwooll, Karl Agger, Christian Wagener, Claude Sardet, Elena Prosperini, Sergio Oddi, M. Cristina Moroni, Peter Steensgaard
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2005, 280 (2), pp.1199-1208. ⟨10.1074/jbc.M412509200⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2005, 280 (2), pp.1199-1208. ⟨10.1074/jbc.M412509200⟩
International audience; The transcriptional repressor E2F6 has been identified as a component of two distinct polycomb group protein (PcG)-containing complexes, suggesting a mechanism for the recruitment of repressive complexes to target sequences in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d36325fbeb60ed97c00f10a6022f5c50
http://hdl.handle.net/11575/12226
http://hdl.handle.net/11575/12226
Autor:
Michael Rugaard Jensen, Emanuela Frittoli, Marina Lomazzi, M. Cristina Moroni, Kristian Helin
Publikováno v:
Nature genetics. 31(2)
Deregulation of the retinoblastoma protein (pRB) pathway is a hallmark of cancer. In the absence of other genetic alterations, this deregulation results in lack of differentiation, hyperproliferation and apoptosis. The pRB protein acts as a transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38c1a841df7c68c0952715971b23d2c5
https://pubmed.ncbi.nlm.nih.gov/11992123
https://pubmed.ncbi.nlm.nih.gov/11992123
Autor:
Elena Vigo, M. Cristina Moroni, Adrian P. Bracken, Kristian Helin, Jonathan D. Oliner, Elena Prosperini, Fred Christians, Richard Vernell, Heiko Muller, Emanuela Grassilli
Publikováno v:
Genesdevelopment. 15(3)
The retinoblastoma protein (pRB) and its two relatives, p107 and p130, regulate development and cell proliferation in part by inhibiting the activity of E2F-regulated promoters. We have used high-density oligonucleotide arrays to identify genes in wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b831c20a0e12ef81cfc9fe6be1066c05
https://pubmed.ncbi.nlm.nih.gov/11159908
https://pubmed.ncbi.nlm.nih.gov/11159908
Autor:
Heiko Müller, Greta Caprara, Kristian Helin, Francesco Cecconi, M. Cristina Moroni, Eros Lazzerini Denchi, Elena Colli, Emma S. Hickman
Loss of function of the retinoblastoma protein, pRB, leads to lack of differentiation, hyperproliferation and apoptosis. Inactivation of pRB results in deregulated E2F activity, which in turn induces entry to S-phase and apoptosis. Induction of apopt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ccdccaa2ce1ac33a25b53e6e4b760d2
http://hdl.handle.net/2108/53623
http://hdl.handle.net/2108/53623