Zobrazeno 1 - 5
of 5
pro vyhledávání: '"M. Cristina Cruz"'
Autor:
Joseph Heitman, M. Cristina Cruz, Hengming Ke, Maria E. Cardenas, Deborah S. Fox, Rey A. L. Sia, Gary M. Cox
Publikováno v:
Molecular Microbiology. 39:835-849
Calcineurin is a Ca2+–calmodulin-regulated protein phosphatase that is the target of the immunosuppressive drugs cyclosporin A and FK506. Calcineurin is a heterodimer composed of a catalytic A and a regulatory B subunit. In previous studies, the ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe2091b766408ebeab6fb26c56f7e3e0
https://doi.org/10.1046/j.1365-2958.2001.02295.x
https://doi.org/10.1046/j.1365-2958.2001.02295.x
Autor:
John R. Perfect, Youssef L. Bennani, Alan L. Goldstein, M. Cristina Cruz, Maria E. Cardenas, John H. McCusker, Maurizio Del Poeta, Joseph Heitman, Jill R. Blankenship
Publikováno v:
Antimicrobial Agents and Chemotherapy. 45:3162-3170
Candida albicans and Cryptococcus neoformans cause both superficial and disseminated infections in humans. Current antifungal therapies for deep-seated infections are limited to amphotericin B, flucytosine, and azoles. A limitation is that commonly u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7851639bd50dc8801fd219dbae60c3a
https://doi.org/10.1128/aac.45.11.3162-3170.2001
https://doi.org/10.1128/aac.45.11.3162-3170.2001
Autor:
John R. Perfect, Namjin Chung, Maria E. Cardenas, M. Cristina Cruz, Joseph Heitman, Maurizio Del Poeta
Publikováno v:
Clinical Microbiology Reviews. 12:583-611
SUMMARY Recent evolutionary studies reveal that microorganisms including yeasts and fungi are more closely related to mammals than was previously appreciated. Possibly as a consequence, many natural-product toxins that have antimicrobial activity are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec31c23cfe716046b2db9f43a7a34ee6
https://doi.org/10.1128/cmr.12.4.583
https://doi.org/10.1128/cmr.12.4.583
Autor:
Maurizio Del Poeta, John R. Perfect, John H. McCusker, M. Cristina Cruz, Alan L. Goldstein, Maria E. Cardenas, Dana A. Davis, Joseph Heitman, Jill R. Blankenship
The immunosuppressants cyclosporin A (CsA) and FK506 inhibit the protein phosphatase calcineurin and block T‐cell activation and transplant rejection. Calcineurin is conserved in microorganisms and plays a general role in stress survival. CsA and F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41725ecc4bc102c2f770f790f01c592a
https://europepmc.org/articles/PMC125859/
https://europepmc.org/articles/PMC125859/
Autor:
Jenifer M. Gorlach, M. Cristina Cruz, Joseph Heitman, Lora M. Cavallo, Maria E. Cardenas, Gary M. Cox, John R. Perfect
Publikováno v:
Molecular and cellular biology. 19(6)
Cryptococcus neoformans is a fungal pathogen that causes meningitis in patients immunocompromised by AIDS, chemotherapy, organ transplantation, or high-dose steroids. Current antifungal drug therapies are limited and suffer from toxic side effects an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4f0c67c5b7158e664f6d28cd9a9db3b
https://pubmed.ncbi.nlm.nih.gov/10330150
https://pubmed.ncbi.nlm.nih.gov/10330150