Zobrazeno 1 - 8
of 8
pro vyhledávání: '"M. Cristina Cruz"'
Autor:
Joseph Heitman, M. Cristina Cruz, Hengming Ke, Maria E. Cardenas, Deborah S. Fox, Rey A. L. Sia, Gary M. Cox
Publikováno v:
Molecular Microbiology. 39:835-849
Calcineurin is a Ca2+–calmodulin-regulated protein phosphatase that is the target of the immunosuppressive drugs cyclosporin A and FK506. Calcineurin is a heterodimer composed of a catalytic A and a regulatory B subunit. In previous studies, the ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe2091b766408ebeab6fb26c56f7e3e0
https://doi.org/10.1046/j.1365-2958.2001.02295.x
https://doi.org/10.1046/j.1365-2958.2001.02295.x
Autor:
John R. Perfect, Youssef L. Bennani, Alan L. Goldstein, M. Cristina Cruz, Maria E. Cardenas, John H. McCusker, Maurizio Del Poeta, Joseph Heitman, Jill R. Blankenship
Publikováno v:
Antimicrobial Agents and Chemotherapy. 45:3162-3170
Candida albicans and Cryptococcus neoformans cause both superficial and disseminated infections in humans. Current antifungal therapies for deep-seated infections are limited to amphotericin B, flucytosine, and azoles. A limitation is that commonly u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7851639bd50dc8801fd219dbae60c3a
https://doi.org/10.1128/aac.45.11.3162-3170.2001
https://doi.org/10.1128/aac.45.11.3162-3170.2001
Autor:
John R. Perfect, Namjin Chung, Maria E. Cardenas, M. Cristina Cruz, Joseph Heitman, Maurizio Del Poeta
Publikováno v:
Clinical Microbiology Reviews. 12:583-611
SUMMARY Recent evolutionary studies reveal that microorganisms including yeasts and fungi are more closely related to mammals than was previously appreciated. Possibly as a consequence, many natural-product toxins that have antimicrobial activity are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec31c23cfe716046b2db9f43a7a34ee6
https://doi.org/10.1128/cmr.12.4.583
https://doi.org/10.1128/cmr.12.4.583
Autor:
Maurizio Del Poeta, John R. Perfect, John H. McCusker, M. Cristina Cruz, Alan L. Goldstein, Maria E. Cardenas, Dana A. Davis, Joseph Heitman, Jill R. Blankenship
The immunosuppressants cyclosporin A (CsA) and FK506 inhibit the protein phosphatase calcineurin and block T‐cell activation and transplant rejection. Calcineurin is conserved in microorganisms and plays a general role in stress survival. CsA and F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41725ecc4bc102c2f770f790f01c592a
https://europepmc.org/articles/PMC125859/
https://europepmc.org/articles/PMC125859/
Autor:
Jenifer M. Gorlach, M. Cristina Cruz, Joseph Heitman, Lora M. Cavallo, Maria E. Cardenas, Gary M. Cox, John R. Perfect
Publikováno v:
Molecular and cellular biology. 19(6)
Cryptococcus neoformans is a fungal pathogen that causes meningitis in patients immunocompromised by AIDS, chemotherapy, organ transplantation, or high-dose steroids. Current antifungal drug therapies are limited and suffer from toxic side effects an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4f0c67c5b7158e664f6d28cd9a9db3b
https://pubmed.ncbi.nlm.nih.gov/10330150
https://pubmed.ncbi.nlm.nih.gov/10330150
Publikováno v:
Journal of Antimicrobial Chemotherapy (JAC); Jun2003, Vol. 51 Issue 6, p1419-1422, 4p
Publikováno v:
Medical Mycology; 2002, Vol. 40 Issue 6, p581-591, 11p
Autor:
Rolf A. Prade, Hans J. Bohnert
This volume provides technical insight on how genomics-oriented studies may be used to bring new understanding to established models of fungal development. The book helps to assess and solve problems associated with multiple copies of genes and prote