Zobrazeno 1 - 10
of 235
pro vyhledávání: '"M. Colacino"'
Publikováno v:
Natural Hazards and Earth System Sciences, Vol 8, Iss 1, Pp 19-35 (2008)
In this study we conduct a numerical analysis of an intense and destructive storm that occurred over Calabria, southern Italy, on 10–12 December 2003. More than 250 mm of precipitation was recorded over a large area in southern Calabria and one sta
Externí odkaz:
https://doaj.org/article/e74897dc26004bd8ac83adf72920255c
Publikováno v:
Advances in Geosciences, Vol 7, Pp 1-8 (2006)
This paper reports preliminary results of a Limited area model Ensemble Prediction System (LEPS), based on RAMS, for eight case studies of moderate-intense precipitation over Calabria, the southernmost tip of the Italian peninsula. LEPS aims to trans
Externí odkaz:
https://doaj.org/article/7953137313b04ba685172a4f8e88cd09
Publikováno v:
Nonlinear Processes in Geophysics, Vol 13, Iss 1, Pp 53-66 (2006)
This paper reports preliminary results for a Limited area model Ensemble Prediction System (LEPS), based on RAMS (Regional Atmospheric Modelling System), for eight case studies of moderate-intense precipitation over Calabria, the southernmost tip of
Externí odkaz:
https://doaj.org/article/f655e48aef914ce78f841afa297ac779
Publikováno v:
Advances in Geosciences, Vol 2, Pp 177-180 (2005)
At Crati Scrl an operational version of RAMS 4.3 (Regional Atmospheric Modeling System) was implemented in January 2001. This paper aims to give a first assessment of model performances for quantitative precipitation forecast (QPF). In essence, the e
Externí odkaz:
https://doaj.org/article/dfc2c77d4c164345ae3809f99c67f24b
Publikováno v:
Annales Geophysicae, Vol 18, Pp 235-246 (2000)
We study the relative importance of sea-land and mountain-valley thermal contrasts in determining the development of thermally forced mesoscale circulations (TFMCs) over a mountainous peninsula. We first analyse the energetics of the problem, and
Externí odkaz:
https://doaj.org/article/479fc5e24be34eaea74408831bc75320
Autor:
C. Rafanelli, M. Colacino
Publikováno v:
Annals of Geophysics, Vol 46, Iss 2 (2003)
In this work after a short introduction on the structure of Programma Nazionale di Ricerche in Antartide, the different researches on atmospheric physics developed by Italian scientists are presented. The international activities are described, wit
Externí odkaz:
https://doaj.org/article/0d73eda171604e0b93c1c6eb9cff7649
Autor:
Anuradha Bhattacharyya, Christopher R. Trotta, Jana Narasimhan, Kari J. Wiedinger, Wencheng Li, Kerstin A. Effenberger, Matthew G. Woll, Minakshi B. Jani, Nicole Risher, Shirley Yeh, Yaofeng Cheng, Nadiya Sydorenko, Young-Choon Moon, Gary M. Karp, Marla Weetall, Amal Dakka, Vijayalakshmi Gabbeta, Nikolai A. Naryshkin, Jason D. Graci, Thomas Tripodi, Amber Southwell, Michael Hayden, Joseph M. Colacino, Stuart W. Peltz
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Here the authors describe the discovery of a class of small molecule splicing modifiers which are orally bioavailable, cross the blood-brain barrier, and lower levels of huntingtin in a mouse model of Huntington’s disease (HD).
Externí odkaz:
https://doaj.org/article/7d4bfc4e0c074bdc9d52a1e84c8c63c4
Autor:
Arthur Branstrom, Liangxian Cao, Bansri Furia, Christopher Trotta, Marianne Santaguida, Jason D. Graci, Joseph M. Colacino, Balmiki Ray, Wencheng Li, Josephine Sheedy, Anna Mollin, Shirley Yeh, Ronald Kong, Richard Sheridan, John D. Baird, Kylie O’Keefe, Robert Spiegel, Elizabeth Goodwin, Suzanne Keating, Marla Weetall
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Blocking the pyrimidine nucleotide de novo synthesis pathway by inhibiting dihydroorotate dehydrogenase (DHODH) results in the cell cycle arrest and/or differentiation of rapidly proliferating cells including activated lymphocytes, cancer cells, or v
Externí odkaz:
https://doaj.org/article/811abbf56e4c48f29740cec2bf4b6b7f
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 2, Pp n/a-n/a (2021)
Abstract 6β‐Hydroxy‐21‐desacetyl deflazacort (6β‐OH‐21‐desDFZ) is a major circulating but not biologically active metabolite of deflazacort (DFZ). In vitro studies were performed to evaluate cytochrome P450 (CYP)‐ and transporter‐me
Externí odkaz:
https://doaj.org/article/edc4027f69594d8aa6d3e780a86ea483
Autor:
Ronald Kong, Jiyuan Ma, Seongwoo Hwang, Young‐Choon Moon, Ellen M. Welch, Marla Weetall, Joseph M. Colacino, Neil Almstead, John Babiak, Elizabeth Goodwin
Publikováno v:
Pharmacology Research & Perspectives, Vol 8, Iss 2, Pp n/a-n/a (2020)
Abstract Ataluren promotes ribosomal readthrough of premature termination codons in mRNA which result from nonsense mutations. In vitro studies were performed to characterize the metabolism and enzyme kinetics of ataluren and its interaction potentia
Externí odkaz:
https://doaj.org/article/eec39a36fe20492083ddc177954b3161