Zobrazeno 1 - 10
of 33
pro vyhledávání: '"M. Clarke Miller"'
Autor:
Subhash Gaddipati, Qingxian Lu, Ramesh Babu Kasetti, M Clarke Miller, Qingjun Lu, John O Trent, Henry J Kaplan, Qiutang Li
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121185 (2015)
The inhibition of NF-κB by genetic deletion or pharmacological inhibition of IKK2 significantly reduces laser-induced choroid neovascularization (CNV). To achieve a sustained and controlled intraocular release of a selective and potent IKK2 inhibito
Externí odkaz:
https://doaj.org/article/94cf95471a67464e961373062e37bb4f
Autor:
Brandon L Jutras, Alicia M Chenail, Christi L Rowland, Dustin Carroll, M Clarke Miller, Tomasz Bykowski, Brian Stevenson
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66683 (2013)
A site-specific DNA-binding protein was purified from Borrelia burgdorferi cytoplasmic extracts, and determined to be a member of the highly conserved SpoVG family. This is the first time a function has been attributed to any of these ubiquitous bact
Externí odkaz:
https://doaj.org/article/188876b7980146c2be7d099babd2685e
Autor:
Brian Stevenson, Henry A Choy, Marija Pinne, Matthew L Rotondi, M Clarke Miller, Edward Demoll, Peter Kraiczy, Anne E Cooley, Trevor P Creamer, Marc A Suchard, Catherine A Brissette, Ashutosh Verma, David A Haake
Publikováno v:
PLoS ONE, Vol 2, Iss 11, p e1188 (2007)
The pathogenic spirochete Leptospira interrogans disseminates throughout its hosts via the bloodstream, then invades and colonizes a variety of host tissues. Infectious leptospires are resistant to killing by their hosts' alternative pathway of compl
Externí odkaz:
https://doaj.org/article/cf75645695ac434ebc9eb6f2120bffb2
Publikováno v:
Environmental entomology. 48(3)
Carotenoids are fundamental precursors for hormones and antioxidants, and insects must acquire carotenoids from their diet. Previous research has shown that insects can selectively absorb dietary carotenoids, often modifying them qualitatively or qua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5742d7fed172ebfab2868f11ac5e3997
https://pubmed.ncbi.nlm.nih.gov/30951592
https://pubmed.ncbi.nlm.nih.gov/30951592
Autor:
M. Clarke Miller
Publikováno v:
Reference Module in Chemistry, Molecular Sciences and Chemical Engineering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c789c528dc0a93087eb252bb21eded0e
https://doi.org/10.1016/b978-0-12-409547-2.14241-6
https://doi.org/10.1016/b978-0-12-409547-2.14241-6
Autor:
William K. Arnold, Robert D. Perry, Jacqueline D. Fetherston, Alexander G. Bobrov, Joseph A. Burlison, Marina Y. Fosso, Olga Kirillina, Sylvie Garneau-Tsodikova, Tiva T. VanCleave, M. Clarke Miller, Matthew B. Lawrenz
Publikováno v:
Metallomics : integrated biometal science. 9(6)
A number of bacterial pathogens require the ZnuABC Zinc (Zn2+) transporter and/or a second Zn2+ transport system to overcome Zn2+ sequestration by mammalian hosts. Previously we have shown that in addition to ZnuABC, Yersinia pestis possesses a secon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d84004d014333ee2732fba14cdc2330
https://pubmed.ncbi.nlm.nih.gov/28540946
https://pubmed.ncbi.nlm.nih.gov/28540946
Autor:
Jason B. Meier, Chayanendu Hait, Jon M. Maguire, Patrick A. Holt, Magdalena M. Dailey, Luigi Petraccone, M. Clarke Miller, John O. Trent
Publikováno v:
Experimental and Molecular Pathology. 86:141-150
The in silico methods for drug discovery are becoming increasingly powerful and useful. That, in combination 13 with increasing computer processor power, in our case using a novel distributed computing grid, has enabled 14 us to greatly enhance our v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6a9701fee04e703706bda2592c878a4
https://doi.org/10.1016/j.yexmp.2009.01.011
https://doi.org/10.1016/j.yexmp.2009.01.011
Autor:
Jacqueline D. Fetherston, Alexander G. Bobrov, M. Clarke Miller, Robert D. Perry, Olga Kirillina, Joseph A. Burlison
Publikováno v:
Molecular Microbiology. 93:759-775
Bacterial pathogens must overcome host sequestration of zinc (Zn(2+) ), an essential micronutrient, during the infectious disease process. While the mechanisms to acquire chelated Zn(2+) by bacteria are largely undefined, many pathogens rely upon the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0841ef41df0e340236447e7e8575946
https://doi.org/10.1111/mmi.12693
https://doi.org/10.1111/mmi.12693
Autor:
Brian Stevenson, Amy Bowman, Brandon L. Jutras, Dustin Carroll, Alicia M. Chenail, M. Clarke Miller, Haining Zhu
Publikováno v:
Journal of Biological Chemistry. 288:26220-26234
The PUR domain is a nucleic acid-binding motif found in critical regulatory proteins of higher eukaryotes and in certain species of bacteria. During investigations into mechanisms by which the Lyme disease spirochete controls synthesis of its Erp sur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c51be5b35c14e44ddc0d2cc15a8ca1d2
https://doi.org/10.1074/jbc.m113.491357
https://doi.org/10.1074/jbc.m113.491357
Polyethylene glycol binding alters human telomere G-quadruplex structure by conformational selection
Autor:
Andrew N. Lane, William L. Dean, M. Clarke Miller, Robert D. Gray, Jonathan B. Chaires, John O. Trent, Robert Buscaglia
Publikováno v:
Nucleic Acids Research
Polyethylene glycols (PEGs) are widely used to perturb the conformations of nucleic acids, including G-quadruplexes. The mechanism by which PEG alters G-quadruplex conformation is poorly understood. We describe here studies designed to determine how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44d080d61b2a36c4ed8e31e9265e2ba6
https://doi.org/10.1093/nar/gkt440
https://doi.org/10.1093/nar/gkt440