Výsledky vyhledávání - "M. Cinquanta"

Phosphorylation of SOS1 on tyrosine 1196 promotes its RAC GEF activity and contributes to BCR-ABL leukemogenesis

Autor: Martina Zobel, Y Rolland, Juri Rappsilber, Anna Lena Illert, Chiara Giuliani, M Cinquanta, Eugenio Santos, S Kreutmair, Giancarlo Pruneri, Emanuela Frittoli, Giorgio Scita, Saverio Minucci, Carmela Gómez, Mogjiborahman Salek, Isabella Pallavicini, Flavia Troglio, Silke Gerboth, Andrea Palamidessi, Fernando C. Baltanás

Publikováno v: Gerboth, S, Frittoli, E, Palamidessi, A, Baltanas, F C, Salek, M, Rappsilber, J, Giuliani, C, Troglio, F, Rolland, Y, Pruneri, G, Kreutmair, S, Pallavicini, I, Zobel, M, Cinquanta, M, Minucci, S, Gomez, C, Santos, E, Illert, A L & Scita, G 2017, ' Phosphorylation of SOS1 on tyrosine 1196 promotes its RAC GEF activity and contributes to BCR-ABL leukemogenesis ', Leukemia, vol. 32, no. 3, pp. 820-827 . https://doi.org/10.1038/leu.2017.267
Digital.CSIC. Repositorio Institucional del CSIC
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Leukemia

Son of Sevenless 1 (SOS1) is a dual guanine nucleotide exchange factor (GEF) that activates the small GTPases RAC and RAS. Although the molecular mechanisms of RAS GEF catalysis have been unveiled, how SOS1 acquires RAC GEF activity and what is the p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cb12c63e4dffbd9e5bca4d69d3fc5d5
https://hdl.handle.net/20.500.11820/bc8340f1-0ae4-4c45-b4ed-5e0ef373b63b

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Effect of Psychological Stress on [35S]TBPS Binding in Rat Brain

Autor: Tiziana Mennini, M. Cinquanta, M C Foddi

Publikováno v: Pharmacology Biochemistry and Behavior. 58:373-377

This study was designed to determine whether psychological stress alters the function of the GABAergic synapse, examined as biochemical changes of [35S]t-butylbicyclophosphorothionate ([35S]TBPS) binding, in unwashed membranes of rat cerebral cortex.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf2e8fdb20d6e94dadfac912bba1f689
https://doi.org/10.1016/s0091-3057(97)00253-0

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Carrier-mediated Serotonin Release Induced by d-Fenfluramine: Studies with Human Neuroblastoma Cells Transfected with a Rat Serotonin Transporter

Autor: M. Cinquanta, Tiziana Mennini, Marco Gobbi, T Ratovitski, Rabi Simantov, D. Crespi

Publikováno v: Neuropharmacology. 36:803-809

The NMB human neuronal cell line, transfected with a newly prepared plasmid expressing rat serotonin transporter (NMB-rSERT), shows specific [3H]5-HT uptake which is blocked by citalopram and fenfluramine (F) stereoisomers with ic 50 values (1 nM, 0.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd4459f37f7d1ae4123040780b4eda2f
https://doi.org/10.1016/s0028-3908(97)00064-6

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Changes in Protein Kinase C and its Presynaptic Substrate B-SO/GAP-43 after Intrauterine Exposure to Methylazoxy-methanol, a Treatment Inducing Cortical and Hippocampal Damage and Cognitive Deficit in Rats

Autor: F. Cattabeni, Mauro Cimino, W.H. Gispen, Alessandra P. Princivalle, Antonio Caputi, P.N.E. de Graan, P. Marini, M. Di Luca, M. Cinquanta

Publikováno v: European Journal of Neuroscience. 7:899-906

The involvement of protein kinase C (PKC)-dependent processes in adaptive and plastic changes underlying neuronal plasticity was tested in an in vivo animal model characterized by targeted cellular ablation of cortical and hippocampal neurons, cognit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ab6dafb03945cd9e50898445eb7b39ef
https://doi.org/10.1111/j.1460-9568.1995.tb01077.x

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Expression studies and mutational analysis of the androgen regulated homeobox gene NKX3.1 in benign and malignant prostate epithelium

Autor: D K, Ornstein, M, Cinquanta, S, Weiler, P H, Duray, M R, Emmert-Buck, C D, Vocke, W M, Linehan, J A, Ferretti

Publikováno v: The Journal of urology. 165(4)

The NKX-3.1gene is an androgen regulated prostate specific homeobox gene that is believed to have a vital role in normal prostate development. In mice the homologue NKx3.1 is exclusively expressed in prostate epithelium. In humans NKX3.1 expression i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::816bb796593ca0abaa1613949815c41f
https://pubmed.ncbi.nlm.nih.gov/11257711

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Changes in protein kinase C and its presynaptic substrate B-50/GAP-43 after intrauterine exposure to methylazoxy-methanol, a treatment inducing cortical and hippocampal damage and cognitive deficit in rats

Autor: M, Di Luca, A, Caputi, M, Cinquanta, M, Cimino, P, Marini, A, Princivalle, P N, De Graan, W H, Gispen, F, Cattabeni

Publikováno v: The European journal of neuroscience. 7(5)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::51a0dafd5a14d5779c94ac08a30d0ee5
https://pubmed.ncbi.nlm.nih.gov/7613626

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Protein kinase C-dependent phosphorylation in prenatally induced microencephaly

Autor: F, Cattabeni, M, Cinquanta, M, Di Luca

Publikováno v: Neurotoxicology. 15(1)

We describe here integrated studies conducted in an animal model of brain malformation induced by prenatal treatment with a potent antimitotic agent, methylazoxymethanol acetate (MAM). When given at gestational day 15, MAM induces a marked and dose-d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0f029a0eef77861902959c7ae98835cd
https://pubmed.ncbi.nlm.nih.gov/8090355

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