Zobrazeno 1 - 10
of 57
pro vyhledávání: '"M. Ciechanowicz‐Rutkowska"'
Publikováno v:
The Journal of Peptide Research. 62:125-133
A correlation between KI (equilibrium dissociation constants) and IC50 (concentration at 50% inhibition) inhibitors for the family of blockers of the small conductance potassium ion channels and their intrinsic characteristics like molecular mass and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::591c802a25ee6bff9caa0649c5cc9190
https://doi.org/10.1034/j.1399-3011.2003.00076.x
https://doi.org/10.1034/j.1399-3011.2003.00076.x
Publikováno v:
Journal of Molecular Structure. 596:215-219
Derivatives of N-substituted amides of α-piperazine-γ-hydroxybutyric acid display anticonvulsant activity. This study was performed on two representative compounds: N-benzylamide of α-(4-phenylpiperazine)-γ-hydroxybutyric acid (1) and N-benzylami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68f60828ef0ed43c6bcc2e29e07e6a45
https://doi.org/10.1016/s0022-2860(01)00722-0
https://doi.org/10.1016/s0022-2860(01)00722-0
Publikováno v:
Journal of Molecular Structure. 555:391-395
The experimental and calculated IR and Raman spectra were compared and analyzed in the range of 1290–1440 cm −1 . The calculations were carried out with semi-empirical AM1 and PM3 parameterization and with Hartree–Fock approximation. The latter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11edfc09b5209c9b08b2b593faf78a84
https://doi.org/10.1016/s0022-2860(00)00625-6
https://doi.org/10.1016/s0022-2860(00)00625-6
Publikováno v:
Journal of Molecular Structure: THEOCHEM. 374:53-61
Seven muscarinic antagonists have been studied by the molecular-mechanics method; minimum-energy conformations were analyzed in a search for geometric descriptors correlating with their activity. Two pharmacophore descriptors were found to discrimina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5ca56ea4b2ec87be3b3e0ce7a895ba4
https://doi.org/10.1016/s0166-1280(96)80063-7
https://doi.org/10.1016/s0166-1280(96)80063-7
Publikováno v:
Magnetic resonance in chemistry
33 (1995): 586–591. doi:10.1002/mrc.1260330716
info:cnr-pdr/source/autori:M. Ciechanowicz-Rutkowska, L. Ragona, F. Greco, L. Zetta, M. Pegna/titolo:Structure elucidation of two diphenylhydantoin derivatives via 1H and 13C NMR spectroscopy/doi:10.1002%2Fmrc.1260330716/rivista:Magnetic resonance in chemistry (Print)/anno:1995/pagina_da:586/pagina_a:591/intervallo_pagine:586–591/volume:33
33 (1995): 586–591. doi:10.1002/mrc.1260330716
info:cnr-pdr/source/autori:M. Ciechanowicz-Rutkowska, L. Ragona, F. Greco, L. Zetta, M. Pegna/titolo:Structure elucidation of two diphenylhydantoin derivatives via 1H and 13C NMR spectroscopy/doi:10.1002%2Fmrc.1260330716/rivista:Magnetic resonance in chemistry (Print)/anno:1995/pagina_da:586/pagina_a:591/intervallo_pagine:586–591/volume:33
The solution conformations of 1-benzyl-5,5-diphenyl-2,4-dioxo-3-imidazolidineacetic acid (AC) and 3-(2,4-dichlorobenzyl)-5,5-diphenyl-2,4-dioxo-1-imidazolidine acetic acid (AD) were studied by proton and carbon NMR spectroscopy. The two drugs have di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62639020efcfb122bf6e80817ff74ef9
https://doi.org/10.1002/mrc.1260330716
https://doi.org/10.1002/mrc.1260330716
Publikováno v:
Journal of Molecular Structure. 348:317-320
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7eb425ac441ec895b9a3af5753ba3ea
https://doi.org/10.1016/0022-2860(95)08652-c
https://doi.org/10.1016/0022-2860(95)08652-c
Autor:
M. Ciechanowicz-Rutkowska, P. Serda, Afif A. El-Assadi, Vida A. Farrar, J. Grochowski, G. Filippini, Jacqueline A. Moore, T. Pilati, Christine N. Hinko
Publikováno v:
Journal of Medicinal Chemistry. 36:3517-3525
Continuing structure-activity studies on the anticonvulsant activity of analogs of N-(benzyloxy)-2-azaspiro[4.4]nonane-1,3-dione (2a), which displayed anti-electroshock seizure (MES) activity and a protective index (TD50/ED50) of > 4.5 are reported.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17572772dcb65a3afac0eda462dcffd5
https://doi.org/10.1021/jm00075a005
https://doi.org/10.1021/jm00075a005
Autor:
D. E. Hibbs, James P. Stables, V. A. Farrar, M. Ciechanowicz‐Rutkowska, I. O. Edafiogho, Jacqueline A. Moore, M. B. Hursthouse, Mariano S. Alexander, Kenneth R. Scott
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c96fe3761b41f7fddbc01df00afe07d
https://doi.org/10.1002/chin.199708232
https://doi.org/10.1002/chin.199708232
Autor:
W. Zankowska-Jasinska, A. Kolasa, M. Ciechanowicz-Rutkowska, A.I. Karaulov, Michael B. Hursthouse
Publikováno v:
Acta Crystallographica Section C Crystal Structure Communications. 48:1257-1260
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e988df23993a797dca449ea11cb4d78
https://doi.org/10.1107/s0108270191014476
https://doi.org/10.1107/s0108270191014476
Publikováno v:
Journal of Crystallographic and Spectroscopic Research. 21:365-373
The reaction of benzoylacetanilide with the excess of POBr3 furnished monomolecular products and the bimolecularβ-[N-phenyl,N-(β-bromo-cinnamoyl)-amino]-cinnamanilide. Its structure was elucidated by means of elemental analysis, IR,1H NMR and mass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3571f3fe8b50a749d7383e309cf9a9d3
https://doi.org/10.1007/bf01156090
https://doi.org/10.1007/bf01156090