Zobrazeno 1 - 10
of 18
pro vyhledávání: '"M. Chelsea Lane"'
Autor:
Matthew S. Walters, M. Chelsea Lane, Patrick D. Vigil, Sara N. Smith, Seth T. Walk, Harry L. T. Mobley
Publikováno v:
mBio, Vol 3, Iss 1 (2012)
ABSTRACT The urinary tract is one of the most frequent sites of bacterial infection in humans. Uropathogenic Escherichia coli (UPEC) strains are the leading cause of urinary tract infections (UTIs) and are responsible for greater than 80% of uncompli
Externí odkaz:
https://doaj.org/article/24d3c2c87f014b66a4392a6e642af90d
Publikováno v:
mBio, Vol 1, Iss 5 (2010)
ABSTRACT Infection with uropathogenic Escherichia coli (UPEC), the causative agent of most uncomplicated urinary tract infections, proceeds in an ascending manner and, if left untreated, may result in bacteremia and urosepsis. To examine the fate of
Externí odkaz:
https://doaj.org/article/a7a320376a0d48a4b04a71d830733b10
Autor:
Amy C. Palin, Galit Alter, Shane Crotty, Ali H. Ellebedy, M. Chelsea Lane, F. Eun-Hyung Lee, Michela Locci, Angela Malaspina, Conrad Mallia, M. Juliana McElrath, Bali Pulendran, Anjali Singh, M. Patricia D’Souza
Publikováno v:
Nat Immunol
Autor:
Thames E. Pickett, Brooke A. Bozick, Alison Deckhut-Augustine, M. Chelsea Lane, Diane J. Post, Jennifer L. Gordon, Alan C. Embry, Wolfgang W. Leitner, Chao Jiang, Erik J Stemmy
Publikováno v:
Vaccine. 38:2751-2757
Animal models that can recapitulate the human immune system are essential for the preclinical development of safe and efficacious vaccines. Development and optimization of representative animal models are key components of the NIAID strategic plan fo
Publikováno v:
PLoS Pathogens, Vol 11, Iss 1, p e1004587 (2015)
The series of events that occurs immediately after pathogen entrance into the body is largely speculative. Key aspects of these events are pathogen dissemination and pathogen interactions with the immune response as the invader moves into deeper tiss
Externí odkaz:
https://doaj.org/article/f9dc49c059dd4289b3d83d2e57713672
Publikováno v:
Infection and Immunity. 83:2855-2861
Vector-borne pathogens are inoculated in the skin of mammals, most likely in the dermis. Despite this, subcutaneous (s.c.) models of infection are broadly used in many fields, including Yersinia pestis pathogenesis. We expand on a previous report whe
Autor:
M. Chelsea Lane, Rodrigo J. Gonzalez, Michelle Palacios, Matthew B. Lawrenz, Jonathan D. Lenz, David G. Cotter, Virginia L. Miller
Publikováno v:
Journal of Bacteriology. 193:5936-5949
Yersinia pestis CO92 has 12 open reading frames encoding putative conventional autotransporters ( yap s), nine of which appear to produce functional proteins. Here, we demonstrate the ability of the Yap proteins to localize to the cell surface of bot
Publikováno v:
Journal of Bacteriology. 191:1382-1392
MR/P fimbriae of uropathogenic Proteus mirabilis undergo invertible element-mediated phase variation whereby an individual bacterium switches between expressing fimbriae (phase ON) and not expressing fimbriae (phase OFF). Under different conditions,
Publikováno v:
Proceedings of the National Academy of Sciences. 104:16669-16674
Uropathogenic Escherichia coli (UPEC) cause most uncomplicated urinary tract infections (UTIs) in humans. Because UTIs are considered to occur in an ascending manner, flagellum-mediated motility has been suggested to contribute to virulence by enabli
Publikováno v:
Journal of Bacteriology. 189:5523-5533
Type 1 fimbriae and flagella have been previously shown to contribute to the virulence of uropathogenic Escherichia coli (UPEC) within the urinary tract. In this study, the relationship between motility and type 1 fimbrial expression was tested for U