Zobrazeno 1 - 10 of 99 pro vyhledávání: '"M. Cazes"'
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In vitroandin vivoeffects of UP 269-6, a new potent orally active nonpeptide angiotensin II receptor antagonist, on vascular smooth muscle cell proliferation
Autor: M. Cazes, V Desangle, F Caussade, Daniel Provost, A. Cloarec, A. Virone‐Oddos
Publikováno v: British Journal of Pharmacology. 120:488-494
1. The present studies were designed to measure the affinity of UP 269-6, a newly developed angiotensin AT1 receptor antagonist, for vascular AT1 receptors from normotensive and hypertensive rats and to investigate in vitro, its effects on angiotensi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7f87f0a1dcfc1a280142a93d5e8c444
https://doi.org/10.1038/sj.bjp.0700897
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Synthesis and angiotensin II receptor antagonist activity of C-linked pyrimidine derivatives
Autor: J. M. Teulon, A. Cloarec, G. Cure, A. Versigny, E Nicolaï, J Goyard, F Caussade, M. Kirchner, M. Cazes, A. Virone‐Oddos
Publikováno v: European Journal of Medicinal Chemistry. 30:365-375
Summary The synthesis and pharmacological activity of nonpeptide angiotensin II (Ang II) receptor antagonists are presented. These 3- N -substituted pyrimidine-4(3 H )-one and 4-O,N,S-substituted pyrimidine derivatives represent a series of C-linked
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::84cbae4bbf5ee6d3632775b534c7fdcc
https://doi.org/10.1016/0223-5234(96)88246-8
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Synthesis and SAR Studies of Novel Triazolopyrimidine Derivatives as Potent, Orally Active Angiotensin II Receptor Antagonists
Autor: Jean-Marie Teulon, Francois Caussade, A. Versigny, M. Cazes, Joel Goyard, M. Kirchner, A. Virone‐Oddos, Alix Cloarec, Gerard Cure, Eric Nicolai
Publikováno v: Journal of Medicinal Chemistry. 37:2371-2386
The synthesis and pharmacological activity of new nonpeptide angiotensin II (AII) receptor antagonists are presented. These [1,2,4]-triazolo[1,5-c]pyrimidine and 1,2,4-triazolo[4,3-c]pyrimidine derivatives represent a new class of bicyclic antagonist
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0f13c1aa97e3786243967b792449605
https://doi.org/10.1021/jm00041a016
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ChemInform Abstract: Synthesis and SAR Studies of Novel Triazolopyrimidine Derivatives as Potent, Orally Active Angiotensin II Receptor Antagonists
Autor: Eric Nicolai, Gerard Cure, A. Virone‐Oddos, M. Kirchner, Alix Cloarec, Francois Caussade, Jean-Marie Teulon, M. Cazes, Joel Goyard, A. Versigny
Publikováno v: ChemInform. 25
The synthesis and pharmacological activity of new nonpeptide angiotensin II (AII) receptor antagonists are presented. These [1,2,4]-triazolo[1,5-c]pyrimidine and 1,2,4-triazolo[4,3-c]pyrimidine derivatives represent a new class of bicyclic antagonist
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fb2fcb6c159eb8c871f3048f8d069d58
https://doi.org/10.1002/chin.199451187
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ChemInform Abstract: Synthesis and Angiotensin II Receptor Antagonist Activity of C-Linked Pyrimidine Derivatives
Autor: J. M. Teulon, A. Cloarec, M. Kirchner, J Goyard, F Caussade, E Nicolaï, M. Cazes, A. Virone‐Oddos, G. Cure, A. Versigny
Publikováno v: ChemInform. 26
Summary The synthesis and pharmacological activity of nonpeptide angiotensin II (Ang II) receptor antagonists are presented. These 3- N -substituted pyrimidine-4(3 H )-one and 4-O,N,S-substituted pyrimidine derivatives represent a series of C-linked
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9acff736f249aff5109fd69e14512df0
https://doi.org/10.1002/chin.199539173
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Traces of Caledonian and Proterozoic crustal features in deep seismic profiles recorded between France and the British Isles
Autor: B. Pinet, O. Gariel, Jean-Pierre Lefort, M. Cazes, Jean-Claude Sibuet, B. Le Gall, C. Bois
Publikováno v: Tectonophysics. 185:21-36
The area between France and the British Isles has undergone three major orogenies since Proterozoic times, the Cadomian-Monian (late Proterozoic), Caledonian (late Silurian-early Devonian) and Variscan (Devonian-Carboniferous). This paper shows that
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::993eed00d7c19e0d2b96411df9d7c7e2
https://doi.org/10.1016/0040-1951(90)90402-t
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Superimposed Variscan, Caledonian and Proterozoic features inferred from deep seismic profiles recorded between southern Ireland, southwestern Britain and western France
Autor: Jean-Claude Sibuet, Jean-Pierre Lefort, O. Gariel, B. Pinet, M. Cazes, C. Bois, B. Le Gall
Publikováno v: Tectonophysics. 177:15-37
From southern Ireland to the northern Bay of Biscay, subduction was active from the Proterozoic to the late Palaeozoic. They led to the Cadomian, Caledonian and Variscan collisions. Features characterizing these three orogenies have been crossed by t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0ea7b1bd7630b6317d8e0c72b4864a3d
https://doi.org/10.1016/0040-1951(90)90272-a
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