Zobrazeno 1 - 10
of 577
pro vyhledávání: '"M. Cash"'
PP 4.27 – 00202 Single-cell RNA sequencing reveals CBD genetic signature in monocyte gene expression
Publikováno v:
Journal of Virus Eradication, Vol 8, Iss , Pp 100235- (2022)
Externí odkaz:
https://doaj.org/article/56b87adcbba04e8cb07f541685eca7f8
Autor:
Luigi Lorenzini, Silvia Ingala, Alle Meije Wink, Joost P.A. Kuijer, Viktor Wottschel, Mathijs Dijsselhof, Carole H. Sudre, Sven Haller, José Luis Molinuevo, Juan Domingo Gispert, David M. Cash, David L. Thomas, Sjoerd B. Vos, Ferran Prados, Jan Petr, Robin Wolz, Alessandro Palombit, Adam J. Schwarz, Gaël Chételat, Pierre Payoux, Carol Di Perri, Joanna M. Wardlaw, Giovanni B. Frisoni, Christopher Foley, Nick C. Fox, Craig Ritchie, Cyril Pernet, Adam Waldman, Frederik Barkhof, Henk J.M.M. Mutsaerts
Publikováno v:
NeuroImage: Clinical, Vol 35, Iss , Pp 103106- (2022)
The European Prevention of Alzheimer Dementia (EPAD) is a multi-center study that aims to characterize the preclinical and prodromal stages of Alzheimer’s Disease. The EPAD imaging dataset includes core (3D T1w, 3D FLAIR) and advanced (ASL, diffusi
Externí odkaz:
https://doaj.org/article/f278a33758574f99a20a09c8038d6580
Automated Brainstem Segmentation Detects Differential Involvement in Atypical Parkinsonian Syndromes
Autor:
Martina Bocchetta, Juan Eugenio Iglesias, Viorica Chelban, Edwin Jabbari, Ruth Lamb, Lucy L. Russell, Caroline V. Greaves, Mollie Neason, David M. Cash, David L. Thomas, Jason D. Warren, John Woodside, Henry Houlden, Huw R. Morris, Jonathan D. Rohrer
Publikováno v:
Journal of Movement Disorders, Vol 13, Iss 1, Pp 39-46 (2020)
Objective Brainstem segmentation has been useful in identifying potential imaging biomarkers for diagnosis and progression in atypical parkinsonian syndromes (APS). However, the majority of work has been performed using manual segmentation, which is
Externí odkaz:
https://doaj.org/article/086030a0abc54efba8a6042898e6698e
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 136-141 (2019)
Abstract Introduction Frontotemporal dementia (FTD) is a heterogeneous neurodegenerative disorder with multiple genetic and pathological causes. It is characterized by both cortical and subcortical atrophies, with previous studies showing early invol
Externí odkaz:
https://doaj.org/article/b87a12416a934ffe9a3e2b90bb450919
Autor:
Martina Bocchetta, Juan Eugenio Iglesias, Lucy L. Russell, Caroline V. Greaves, Charles R. Marshall, Marzia A. Scelsi, David M. Cash, Sebastien Ourselin, Jason D. Warren, Jonathan D. Rohrer
Publikováno v:
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-9 (2019)
Abstract Background Semantic variant of primary progressive aphasia (svPPA) is a subtype of frontotemporal dementia characterized by asymmetric temporal atrophy. Methods We investigated the pattern of medial temporal lobe atrophy in 24 svPPA patients
Externí odkaz:
https://doaj.org/article/de783a025e1c454090fc3dc1c80bcd77
Autor:
Sarah-Naomi James, Jennifer M. Nicholas, Kirsty Lu, Ashvini Keshavan, Christopher A. Lane, Thomas Parker, Sarah M. Buchanan, Sarah E. Keuss, Heidi Murray-Smith, Andrew Wong, David M. Cash, Ian B. Malone, Josephine Barnes, Carole H. Sudre, William Coath, Marc Modat, Sebastien Ourselin, Sebastian J. Crutch, Diana Kuh, Nick C. Fox, Jonathan M. Schott, Marcus Richards
Publikováno v:
Neurobiology of Aging, 122, 22-32. Elsevier Inc.
James, S-N, Nicholas, J M, Lu, K, Keshavan, A, Lane, C A, Parker, T, Buchanan, S M, Keuss, S E, Murray-Smith, H, Wong, A, Cash, D M, Malone, I B, Barnes, J, Sudre, C H, Coath, W, Modat, M, Ourselin, S, Crutch, S J, Kuh, D, Fox, N C, Schott, J M & Richards, M 2023, ' Adulthood cognitive trajectories over 26 years and brain health at 70 years of age : findings from the 1946 British Birth Cohort ', Neurobiology of Aging, vol. 122, pp. 22-32 . https://doi.org/10.1016/j.neurobiolaging.2022.10.003
James, S-N, Nicholas, J M, Lu, K, Keshavan, A, Lane, C A, Parker, T, Buchanan, S M, Keuss, S E, Murray-Smith, H, Wong, A, Cash, D M, Malone, I B, Barnes, J, Sudre, C H, Coath, W, Modat, M, Ourselin, S, Crutch, S J, Kuh, D, Fox, N C, Schott, J M & Richards, M 2023, ' Adulthood cognitive trajectories over 26 years and brain health at 70 years of age : findings from the 1946 British Birth Cohort ', Neurobiology of Aging, vol. 122, pp. 22-32 . https://doi.org/10.1016/j.neurobiolaging.2022.10.003
Few studies can address how adulthood cognitive trajectories relate to brain health in 70-year-olds. Participants (n = 468, 49% female) from the 1946 British birth cohort underwent 18F-Florbetapir PET/MRI. Cognitive function was measured in childhood
Autor:
Ashvini Keshavan, Henrietta Wellington, Zhongbo Chen, Ayesha Khatun, Miles Chapman, Melanie Hart, David M. Cash, William Coath, Thomas D. Parker, Sarah M. Buchanan, Sarah E. Keuss, Matthew J. Harris, Heidi Murray‐Smith, Amanda Heslegrave, Nick C. Fox, Henrik Zetterberg, Jonathan M Schott
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract INTRODUCTION We assessed the concordance of cerebrospinal fluid (CSF) amyloid beta (Aβ) and tau measured on the fully automated Lumipulse platform with pre‐symptomatic Alzheimer's disease (AD) pathology on amyloid positron emission tomogr
Externí odkaz:
https://doaj.org/article/6d192a34b4fb4435b96b930df6feef2f
Autor:
Ophir Keret, Adam M. Staffaroni, John M. Ringman, Yann Cobigo, Sheng‐Yang M. Goh, Amy Wolf, Isabel Elaine Allen, Stephen Salloway, Jasmeer Chhatwal, Adam M. Brickman, Dolly Reyes‐Dumeyer, Randal J. Bateman, Tammie L.S. Benzinger, John C. Morris, Beau M. Ances, Nelly Joseph‐Mathurin, Richard J. Perrin, Brian A. Gordon, Johannes Levin, Jonathan Vöglein, Mathias Jucker, Christian laFougère, Ralph N. Martins, Hamid R. Sohrabi, Kevin Taddei, Victor L. Villemagne, Peter R. Schofield, William S. Brooks, Michael Fulham, Colin L. Masters, Bernardino Ghetti, Andrew J. Saykin, Clifford R. Jack, Neill R. Graff‐Radford, Michael Weiner, David M. Cash, Ricardo F. Allegri, Patricio Chrem, Su Yi, Bruce L. Miller, Gil D. Rabinovici, Howard J. Rosen, Dominantly Inherited Alzheimer Network
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction Asymptomatic and mildly symptomatic dominantly inherited Alzheimer's disease mutation carriers (DIAD‐MC) are ideal candidates for preventative treatment trials aimed at delaying or preventing dementia onset. Brain atrophy is a
Externí odkaz:
https://doaj.org/article/90049bc6e3de456c9fce7e852de2612b
Autor:
Rhian S. Convery, Mollie R. Neason, David M. Cash, M. Jorge Cardoso, Marc Modat, Sebastien Ourselin, Jason D. Warren, Jonathan D. Rohrer, Martina Bocchetta
Publikováno v:
NeuroImage: Clinical, Vol 26, Iss , Pp - (2020)
Background: The basal forebrain is a subcortical structure that plays an important role in learning, attention, and memory. Despite the known subcortical involvement in frontotemporal dementia (FTD), there is little research into the role of the basa
Externí odkaz:
https://doaj.org/article/0756d016f4ae4067a90fc39d3aadc8b1
Autor:
Giorgio G. Fumagalli, Paola Basilico, Andrea Arighi, Martina Bocchetta, Katrina M. Dick, David M. Cash, Sophie Harding, Matteo Mercurio, Chiara Fenoglio, Anna M. Pietroboni, Laura Ghezzi, John van Swieten, Barbara Borroni, Alexandre de Mendonça, Mario Masellis, Maria C. Tartaglia, James B. Rowe, Caroline Graff, Fabrizio Tagliavini, Giovanni B. Frisoni, Robert Laforce, Elizabeth Finger, Sandro Sorbi, Elio Scarpini, Jonathan D. Rohrer, Daniela Galimberti, on behalf of the Genetic FTD Initiative (GENFI)
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-9 (2018)
Abstract Background In patients with frontotemporal dementia, it has been shown that brain atrophy occurs earliest in the anterior cingulate, insula and frontal lobes. We used visual rating scales to investigate whether identifying atrophy in these a
Externí odkaz:
https://doaj.org/article/11b92a883e244953bc3d04bc14e476ee