Zobrazeno 1 - 10
of 15
pro vyhledávání: '"M. Carmen Garcia-Pelayo"'
Autor:
Pedro J. Sánchez-Cordón, John Spiropoulos, Daryan A. Kaveh, Philip J. Hogarth, M. Carmen Garcia-Pelayo, Naomi Bull
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Heterologous BCG prime-boost regimens represent a promising strategy for an urgently required improved tuberculosis vaccine. Identifying the mechanisms which underpin the enhanced protection induced by such strategies is one key aim which would signi
Autor:
Laura Sibley, Daryan A. Kaveh, Philip J. Hogarth, Paul R. Webb, M. Carmen Garcia-Pelayo, Simon M. Cutting, Naomi Bull
Publikováno v:
Tuberculosis. 98:97-103
SummaryTuberculosis (TB) remains a global pandemic, in both animals and man, and novel vaccines are urgently required. Heterologous prime-boost of BCG represents a promising strategy for improved TB vaccines, with respiratory delivery the most effica
Publikováno v:
Tuberculosis. 95:48-53
summary It is generally assumed that the inbred mouse strains BALB/c (H-2 d ) and C57BL/6 (H-2 b ) respond to mycobacterial infection with distinct polarisation of T helper responses, with C57BL/6 predisposed toTh1 and BALB/c to Th2. We investigated
Publikováno v:
Frontiers in Life Science. 7:123-131
Cell membrane proteins are sensitive to their fatty acid environment; however, the effects of those fatty acids are not completely understood. In this work, we have optimized a model for the study of membrane protein regulation, which allows the inve
Autor:
M. Carmen Garcia-Pelayo, Daryan A. Kaveh, Paul R. Webb, Esen Wooff, Philip J. Hogarth, Véronique S. Bachy
Publikováno v:
Vaccine. 34(34)
Boosting BCG using heterologous prime-boost represents a promising strategy for improved tuberculosis (TB) vaccines, and adenovirus (Ad) delivery is established as an efficacious boosting vehicle. Although studies demonstrate that intranasal administ
Autor:
Sabrina Rodriguez-Campos, Maria Lodovica Pacciarini, Ana Botelho, Amanda J. Lohan, M. Carmen Garcia-Pelayo, Beatriz Romero, Lucía de Juan, Stefan Berg, Noel H. Smith, Lucas Domínguez, R. Glyn Hewinson, Brendan J. Loftus, Mónica V. Cunha, Stephen V. Gordon, Dick van Soolingen, James Dale, Krystel de Cruz, Anita C. Schürch, M. Beatrice Boniotti, M. Laura Boschiroli, Alicia Aranaz
Publikováno v:
Infection, Genetics and Evolution, 12, 866-72
Infection, Genetics and Evolution, 12, 4, pp. 866-72
Infection, Genetics and Evolution, 12, 4, pp. 866-72
Contains fulltext : 107786.pdf (Publisher’s version ) (Closed access) Mycobacterium bovis isolates from the Iberian Peninsula are dominated by strains with spoligotype patterns deleted for spacer 21. Whole-genome sequencing of three Spanish strains
Autor:
Abraham Aseffa, Rudovick Kazwala, Markus Hilty, Simeon Cadmus, Gunilla Källenius, Moses Joloba, Rebuma Firdessa, Jakob Zinsstag, Adelina Machado, Stefan Berg, Kristin Kremer, Dick van Soolingen, Custodia Mucavele, R. Glyn Hewinson, M. Carmen Garcia-Pelayo, Benon B. Asiimwe, Leen Rigouts, Judith Bruchfeld, Françoise Portaels, Elena Hailu, Stephen V. Gordon, Anita Luise Michel, Alicia Aranaz, Sabrina Rodríguez, Naima Sahraoui, Paul D. van Helden, M. Beatrice Boniotti, Noel H. Smith, Bongo Naré Richard Ngandolo, James Dale, Annélle Müller, Berit Djønne, Maria Lodovica Pacciarini, Borna Müller, Laura Boschiroli
Publikováno v:
Europe PubMed Central
Journal of Bacteriology, 193, 670-8
Journal of Bacteriology, 193, 3, pp. 670-8
Journal of Bacteriology, 193, 670-8
Journal of Bacteriology, 193, 3, pp. 670-8
We have identified a clonal complex of Mycobacterium bovis isolated at high frequency from cattle in Uganda, Burundi, Tanzania, and Ethiopia. We have named this related group of M. bovis strains the African 2 (Af2) clonal complex of M. bovis. Af2 str
Autor:
Pablo Mendoza Lopez, Kevin C. Conlon, Julio Polaina, Antonio Suárez García, Stephen V. Gordon, Javier Nunez Garcia, R. Glyn Hewinson, Esen Wooff, M. Carmen Garcia Pelayo, Ana Camacho, Paul Golby
Publikováno v:
Microbiology; Vol 156
Microbiology
Microbiology
A number of single-nucleotide polymorphisms (SNPs) have been identified in the genome of Mycobacterium bovis BCG Pasteur compared with the sequenced strain M. bovis 2122/97. The functional consequences of many of these mutations remain to be describe
Autor:
Thierry Garnier, R. Glyn Hewinson, Stewart T. Cole, Julian Parkhill, Javier Nunez Garcia, Xiangmei Zhou, Pablo Mendoza Lopez, Noel H. Smith, Laura Boschiroli, Stephen V. Gordon, M. Carmen Garcia Pelayo, Swapna Uplekar, Andrew Keniry
Publikováno v:
Infection and Immunity. 77:2230-2238
To further unravel the mechanisms responsible for attenuation of the tuberculosis vaccine Mycobacterium bovis BCG, comparative genomics was used to identify single nucleotide polymorphisms (SNPs) that differed between sequenced strains of Mycobacteri
Autor:
Paul Golby, Andrea Peralta, Fabiana Bigi, Javier Nunez-Garcia, Jason Hinds, Stephen V. Gordon, Karina Cynthia Caimi, M. Carmen Garcia-Pelayo, Maria Isabel Romano, Ángel Adrián Cataldi
Publikováno v:
FEMS Microbiology Letters. 248:147-152
Tuberculosis in seals is caused by Mycobacterium pinnipedii, a member of the Mycobacterium tuberculosis complex. In this study, we evaluated the extent of genetic variability among Mycobacterium bovis and M. pinnipedii by microarray-based comparative