Zobrazeno 1 - 7
of 7
pro vyhledávání: '"M. C. Woodle"'
Autor:
Terry Beck, Andrew Webb, Ian Judson, M. C. Woodle, M. Dizik, Florence I. Raynaud, J. A. Jaeger, David Cunningham, E. McCampbell, A. V. Lebedev, B. D. Brown, Timothy A. Riley
Publikováno v:
Nucleosides and Nucleotides. 16:1683-1687
An HPLC assay has been developed to determine plasma levels of G3139 - a 18mer phosphorothioate oligonucleotide currently in Phase I clinical studies. The assay utilizes anion exchange microchromatography, aqueous LiBr gradient elution, and UV absorb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a0258bc68bc28378ff0adb7389bdf62
https://doi.org/10.1080/07328319708006255
https://doi.org/10.1080/07328319708006255
Autor:
Ian Judson, M. Dizik, B. D. Brown, Demetrios Papahadjopoulos, M. C. Woodle, Rosanne M. Orr, S. K. Huang, Florence I. Raynaud, J. A. Jaeger, Olivier Meyer
Publikováno v:
Nucleosides and Nucleotides. 16:1731-1734
G3139, an 18mer phosphorothioate, down regulates BCL2 and is efficacious in human xenograft tumor models. Studies of pharmacokinetics, toxicology, and influence of formulations on the biological properties of G3139 in mice are described. Bioavailabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::877035c4daa686a497845f22ec2dac7e
https://doi.org/10.1080/07328319708006265
https://doi.org/10.1080/07328319708006265
Publikováno v:
British Journal of Cancer
Long-circulating (stealth) liposomes coated with polyethylene glycol (PEG), which show reduced uptake by the reticuloendothelial system (RES) and enhanced accumulation in tumours, were used for conjugation to monoclonal antibodies (MAbs) as a drug-ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a53749a63092665307a4fc3e7c9ac8
http://europepmc.org/articles/PMC2077226
http://europepmc.org/articles/PMC2077226
Autor:
Irma A. J. M. Bakker-Woudenberg, G. Blume, Gert Storm, M. C. Woodle, Hidde J. Haisma, D.J.A. Crommelin, M. H. Vingerhoeds, U. K. Nässander
Publikováno v:
Targeting of Drugs 4 ISBN: 9781489912091
Delivery of the drug at a specific site (drug targeting) or controlled and/or prolonged release of the liposome-bound drug are the major considerations for adding liposomes to the existing arsenal of drug delivery systems. In particular the concept o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6249e8cbc7855e485d71f9c5d0b0833
https://doi.org/10.1007/978-1-4899-1207-7_11
https://doi.org/10.1007/978-1-4899-1207-7_11
Autor:
M. C. Woodle, M. T. ten Kate, Johan W. Mouton, Gert Storm, August F. Lokerse, Irma A. J. M. Bakker-Woudenberg
Publikováno v:
The Journal of infectious diseases. 168(1)
Studies of two types of small liposomes, differing with respect to their lipid composition in terms of bilayer fluidity, charge, and hydrophilicity of the liposomal surface, were done to evaluate their usefulness for delivery of encapsulated therapeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7979301418536decdbf418386baa9bb
https://pubmed.ncbi.nlm.nih.gov/8515105
https://pubmed.ncbi.nlm.nih.gov/8515105
Publikováno v:
Pharmaceutical research. 9(2)
The value of novel systemically long-circulating liposomes to prolong the duration of an antidiuretic hormone, arg8-vasopressin (VP), was investigated as a representative of low molecular weight peptides with rapid clearance. Cholesterol content was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5f38c399ca6b17a7af6d329bf954ddd7
https://pubmed.ncbi.nlm.nih.gov/1553352
https://pubmed.ncbi.nlm.nih.gov/1553352
Autor:
M C, Woodle, D, Papahadjopoulos
Publikováno v:
Methods in enzymology. 171
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c37d0cdcc63422ba31b41d640c41e50f
https://pubmed.ncbi.nlm.nih.gov/2593841
https://pubmed.ncbi.nlm.nih.gov/2593841