Exploring Immune Development in Infants With Moderate to Severe Atopic Dermatitis

Autor: Lies Hulshof, Saskia A. Overbeek, Anne L. Wyllie, Mei Ling J. N. Chu, Debby Bogaert, Wilco de Jager, Leon M. J. Knippels, Elisabeth A. M. Sanders, Wim M. C. van Aalderen, Johan Garssen, Belinda van’t Land, Aline B. Sprikkelman, The Clinical Study Group, A. Blauw, B. Dontje, Y. C. M. Duijvestein, W. H. C. de Boom, I. Groot, M. Boks, Y. van Kooyk, D. H. H. Fandri, D. Hijnen, M. A. Middelkamp-Hup, B. Papi, M. Roelofs, A. Rijnierse, D. Veening, Clinical Trial Support, B. J. Prakken, G. W. Ten Tusscher, R. A. Tupker, L. E. M. Willemsen

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

BackgroundAtopic dermatitis (AD) is the most common chronic inflammatory skin disease in infancy with a complex pathology. In adults, the clinical severity of AD has been associated with increases in T helper cell type (Th) 2, Th22, and Th17 serum ma

Externí odkaz: https://doaj.org/article/2ac28a6b276d42c296dde81fb54acb95

Prediction of asthma in early preschool wheezing by electronic nose analysis

Autor: Peter J. Sterk, Anke H. Maitland-van der Zee, Ivo A van den Bongaardt, Suzanne W J Terheggen-Lagro, Niels W. Rutjes, Marc P. van der Schee, Wim M. C. van Aalderen, Paul Brinkman, Eric G. Haarman, Simone Hashimoto

Publikováno v: Pediatric and Allergy Immunology, 33(1):e13612. Blackwell Munksgaard
Rutjes, N, Van den Bongaardt, I, Hashimoto, S, Sterk, P, Van Aalderen, W, Terheggen-Lagro, S, Brinkman, P, Maitland-van der Zee, A-H, Van der Schee, M & Haarman, E 2022, ' Prediction of asthma in early preschool wheezing by electronic nose analysis ', Pediatric and Allergy Immunology, vol. 33, no. 1, e13612, pp. e13612 . https://doi.org/10.1111/pai.13612
Pediatric allergy and immunology, 33(1):e13612. Blackwell Munksgaard

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a523d002b76348137a3e7085844ffc38
https://doi.org/10.1111/pai.13612

Connectivity patterns between multiple allergen specific IgE antibodies and their association with severe asthma

Autor: Custovic Adnan, Sara Fontanella, Louise Fleming, Peter Brinkman, Florian Singer, Graham Roberts, Rebecca Howard, Clare S. Murray, Simone Hashimoto, Wim M. C. van Aalderen, Peter J. Sterk, Ratko Djukanovic, Urs Frey, Gunilla Hedlin, Björn Nordlund, Peter H. Howarth, Anna Selby, Andrew Bush, Ann-Marie Malby Schoos, K. Fan Chung, Sarah Filippi

Publikováno v: Journal of allergy and clinical immunology, 146(4), 821-830. Mosby Inc.

Background: Allergic sensitization is associated with severe asthma, but assessment of sensitization is not recommended by most guidelines. Objective: We hypothesized that patterns of IgE responses to multiple allergenic proteins differ between sensi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::000f8ec870a77b8284af8589fffcec1e
https://pure.amc.nl/en/publications/connectivity-patterns-between-multiple-allergen-specific-ige-antibodies-and-their-association-with-severe-asthma(26ff3aea-0bd6-445b-8829-ff347d622f6f).html

Severe paediatric asthma collaborative in Europe (SPACE): Protocol for a european registry

Autor: Monika Gappa, Louise Fleming, Jonathan Grigg, Karin C. Lødrup Carlsen, Courtney Coleman, Ricardo M. Fernandes, Fabio Midulla, Niels W. Rutjes, James D. Chalmers, Franca Rusconi, Mariëlle W. Pijnenburg, Steve Cunningham, Bulent Karadag, Norrice M. Liu, Wim M. C. van Aalderen

Publikováno v: Breathe, Vol 14, Iss 2, Pp 93-98 (2018)
Liu, N M, van Aalderen, W, Carlsen, K C L, Coleman, C, Chalmers, J D, Cunningham, S, Fernandes, R M, Fleming, L J, Gappa, M, Karadag, B, Midulla, F, Pijnenburg, M W H, Rutjes, N W, Rusconi, F & Grigg, J 2018, ' Severe Paediatric Asthma Collaborative in Europe (SPACE) : protocol for a European registry ', Breathe, vol. 14, no. 2, pp. 93-98 . https://doi.org/10.1183/20734735.002018
Breathe, 14(2), 93-99. European Respiratory Society
Breathe

The development of new asthma biologics and receptor blockers for the treatment of paediatric severe asthma raises challenges. It is unclear whether there are sufficient children in Europe to recruit into randomised placebo-controlled trials to estab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c50ab45427eaee3c793a3f93a686605b
https://doi.org/10.1183/20734735.002018

Asthma-Related Outcomes in Patients Initiating Extrafine Ciclesonide or Fine-Particle Inhaled Corticosteroids

Autor: David Price, Javaria Mona Khalid, Jetty A. Overbeek, Elliot Israel, Victoria Thomas, Ron M. C. Herings, Elizabeth V. Hillyer, Wim M. C. van Aalderen, Nicolas Roche, Richard Dekhuijzen, Theresa W. Guilbert, Thys van der Molen, Dirkje S. Postma, Daniela van Eickels, Catherine Hutton, Cristiana Miglio, Richard J. Martin

Publikováno v: Allergy Asthma & Immunology Research, 9, 2, pp. 116-125
Allergy asthma & immunology research, 9(2), 116-125. KOREAN ACAD ASTHMA ALLERGY & CLINICAL IMMUNOLOGY
Allergy, Asthma & Immunology Research
Postma, D S, Dekhuijzen, R, van der Molen, T, Martin, R J, van Aalderen, W, Roche, N, Guilbert, T W, Israel, E, van Eickels, D, Khalid, J M, Herings, R M C, Overbeek, J A, Miglio, C, Thomas, V, Hutton, C, Hillyer, E V & Price, D B 2017, ' Asthma-Related Outcomes in Patients Initiating Extrafine Ciclesonide or Fine-Particle Inhaled Corticosteroids ', Allergy, asthma & immunology research, vol. 9, no. 2, pp. 116-125 . https://doi.org/10.4168/aair.2017.9.2.116
Allergy, asthma & immunology research, 9(2), 116-125
Allergy, asthma and immunology research, 9(2), 116-125. Korean Academy of Asthma, Allergy and Clinical Immunology
Allergy Asthma & Immunology Research, 9, 116-125

PURPOSE: Extrafine-particle inhaled corticosteroids (ICS) have greater small airway deposition than standard fine-particle ICS. We sought to compare asthma-related outcomes after patients initiated extrafine-particle ciclesonide or fine-particle ICS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::086210d0f1940cae9a27948442a70e09
https://doi.org/10.4168/aair.2017.9.2.116