Imatinib mesylate ameliorates the dystrophic phenotype in exercised mdx mice

Autor: Juliana Caldas Ribeiro, Lilian Cataldi Rodrigues, M. C. R. Costa, Paula Sakemi Fukuhara, Fabíola Attié de Castro, Gislane Lelis Vilela de Oliveira, João C. S. Bizario, Daniel Giuliano Cerri, Auro Nomizo, Daniela Dover de Araújo

Publikováno v: Journal of Neuroimmunology. 212:93-101

Myofiber degeneration, inflammation, and fibrosis are remarkable features of Duchenne muscular dystrophy. We hypothesized that the administration of imatinib mesylate, an inhibitor of tyrosine kinase and TGF-beta pro-fibrogenic activity, could improv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1bec0274aabdd667fe381e1cc657d86
https://doi.org/10.1016/j.jneuroim.2009.05.006

SOD2 immunoexpression predicts lymph node metastasis in penile cancer

Autor: Enrique Boccardo, Gustavo Cardoso Guimarães, M. C. R. Costa, José Humberto Tavares Guerreiro Fregnani, Walter Henriques da Costa, Adhemar Longatto-Filho, Luisa L. Villa, Lara Termini, Ademar Lopes, Fernando Augusto Soares, Isabela Werneck da Cunha, Maria Antonieta Andreoli

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
BMC Clinical Pathology

BACKGROUND: Superoxide dismutase-2 (SOD2) is considered one of the most important antioxidant enzymes that regulate cellular redox state in normal and tumorigenic cells. Overexpression of this enzyme in lung, gastric, colorectal, breast cancer and ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6abc053575b816fba34850b20218885d
https://hdl.handle.net/1822/34398

The contribution of 700,000 ORF sequence tags to the definition of the human transcriptome

Autor: Daniel F. Simão, Luis F.L. Reis, Vanderlei Rodrigues, Dirce Maria Carraro, Marco Antônio Zago, Ismael Dale Cotrim Guerreiro da Silva, Rui M. B. Maciel, Heloisa Zalcberg, Alex F. Carvalho, Maria Lucia C. Corrêa, Daniela C. Miranda, Paula Rahal, Ari J. S. Ferreira, E. C. Miracca, Silvia Regina Rogatto, Ana L. T. O. Nascimento, Simone Cristina Sant'anna, Andrew J. G. Simpson, Nancy da Rós, Wilson A. Silva, Maria E. R. de Camargo, Christine Hackel, Gilberto K. Furuzawa, Fernando Lopes Alberto, Gustavo H. Goldman, Vanessa Bombonato, Elida B. Ojopi, Aline Maria Da Silva, Cláudia Aparecida Rainho, Angela Maria de Assis, Maria de Fátima Sonati, Maria Aparecida Nagai, Rosana F. R. Corrêa, Hamza El-Dorry, Maria Luísa Paço-Larson, Sergio Verjovski-Almeida, Nádia Aparecida Bérgamo, Fernando Augusto Soares, Mari Cleide Sogayar, Valeria Valente, Maria Inês de Moura Campos Pardini, Aline C. Prevedel, Arthur Gruber, Analy Salles de Azevedo Melo, Anamaria A. Camargo, Mozart Marins, Sandro Roberto Valentini, Janete M. Cerutti, Mariana Lopes dos Santos, Marina P. Nobrega, Francisco G. Nobrega, Eloiza H. Tajara, M. E. J. Amaral, Edna Teruko Kimura, Italo A. Migotto, Marcelo Lima Ribeiro, Daniel Giannella-Neto, Josane F. Sousa, M B Melo, Paula de Oliveira Montandon Hokama, José Rodrigo C. Pandolfi, Ricardo R. Brentani, Diana N. Nunes, Renata de Azevedo Canevari, Fernando Tsukumo, Liliane A. T. Arnaldi, Renata G. de Sá, Ivy Aneas, Elizabeth A. L. Martins, Mario H. Bengtson, Elza Kimura, Emmanuel Dias-Neto, Eduardo M. Reis, Daniella Stecconi, Suely Kazue Nagahashi Marie, Paromita Majumder, Rosana A Silveira, Carlos Alberto Mestriner, Enilza Maria Espreáfico, M. C. R. Costa, João Bosco Pesquero, Luciana C. C. Leite, José Eduardo Krieger, Sandro J. de Souza, Helena B. Samaia, Gonçalo A.G. Pereira, Helaine Carrer, Magaly M. Sales, Paulo L. Ho, Everaldo dos Reis Marques, Fernando Ferreira Costa, Ricardo G. Correa, Neusa Pereira da Silva, Angelita Habr-Gama, Luciana Gilbert Pessoa, Eloisa de Sá Moreira, Tsieko Gushiken, Cyntia Curcio, Luis Eduardo Coelho Andrade, Marcelo R.S. Briones

Publikováno v: Proceedings of the National Academy of Sciences. 98:12103-12108

Open reading frame expressed sequences tags (ORESTES) differ from conventional ESTs by providing sequence data from the central protein coding portion of transcripts. We generated a total of 696,745 ORESTES sequences from 24 human tissues and used a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3715fbfcb26b426fe349fa03a08d6b2c
https://doi.org/10.1073/pnas.201182798

Identification of human chromosome 22 transcribed sequences with ORF expressed sequence tags

Autor: Sandro J. de Souza, Analy Salles de Azevedo Melo, Eloiza H. Tajara, Andrew J. G. Simpson, Fernando Ferreira Costa, Elida B. Ojopi, Luis Eduardo Coelho Andrade, Edna Teruko Kimura, Luciana C. C. Leite, Marco Antônio Zago, Helaine Carrer, Sandro Roberto Valentini, Magaly M. Sales, Fernando Lopes Alberto, Marcelo R.S. Briones, Ricardo R. Brentani, Gustavo H. Goldman, Lúcia Helena Carvalho, Paromita Majumder, Francisco G. Nobrega, Paulo L. Ho, Alex F. Carvalho, Maria Luísa Paço-Larson, José Rodrigo C. Pandolfi, M. E. J. Amaral, Daniel F. Simão, Gustavo Maia, Silvia Regina Rogatto, E. C. Miracca, Elizabeth A. L. Martins, Elza Kimura, Carlos Alberto Mestriner, Janete M. Cerutti, M. C. R. Costa, Hamza El-Dorry, Enilza Maria Espreáfico, Christine Hackel, Luis F.L. Reis, Dirce Maria Carraro, João Bosco Pesquero, Mario H. Bengtson, Ismael Dale Cotrim Guerreiro da Silva, Rui M. B. Maciel, Sergio Verjovski-Almeida, Maria Inês de Moura Campos Pardini, Daniella Stecconi, Tereza Cristina Lima Silva, Renata G. de Sá, Mozart Marins, Arthur Gruber, Mari Cleide Sogayar, Valeria Valente, I. Anéas, Suely Kazue Nagahashi Marie, Maria de Fátima Sonati, Wilson da Silva, Gonçalo A.G. Pereira, Vanderlei Rodrigues, Heloisa Zalcberg, Maria Aparecida Nagai, Fernando Tsukumo, Daniela C. Miranda, Paula Rahal, Emmanuel Dias-Neto, Adriana Yamaguti Matsukuma, Cláudia Aparecida Rainho, Josane F. Sousa, Tsieko Gushiken, Cyntia Curcio, Maria Lucia C. Corrêa, Daniel Giannella-Neto, Ana L. T. O. Nascimento, Nancy da Rós, Neusa Pereira da Silva, Angelita Habr-Gama, Marcio Luis Acencio, Anamaria A. Camargo, Marina P. Nobrega, Luciana Gilbert Pessoa

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Transcribed sequences in the human genome can be identified with confidence only by alignment with sequences derived from cDNAs synthesized from naturally occurring mRNAs. We constructed a set of 250,000 cDNAs that represent partial expressed gene se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::069091379ad4727d73fa8f11054e1e25
https://doi.org/10.1073/pnas.97.23.12690

Microwave-stimulated recovery of myosin-V immunoreactivity from formalin-fixed, paraffin-embedded human CNS

Autor: Minna M. Dias, M. C. R. Costa, Thaisa M. Vasconcelos, Antonio Roberto Martins, Leila Chimelli, Roy E. Larson, Hildeberto Caldo

Publikováno v: Journal of Neuroscience Methods. 92:25-29

The lability of brain myosin-V (BM-V) to aldehyde-fixation has hindered immunohistochemical (IH) studies of this actin-based motor. We show here that BM-V immunoreactivity (IR) can be retrieved from formalin-fixed, paraffin-embedded human tissue. BM-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d614ab1d6db74c7e14352ebd2848c693
https://doi.org/10.1016/s0165-0270(99)00090-4