Zobrazeno 1 - 8
of 8
pro vyhledávání: '"M. C. P. Braat"'
Autor:
M. C. P. Braat, C. J. van Boxtel, J. J. Butter, M.G.J. Koolen, B. T. J. van den Berg, M. G. M. Derks
Publikováno v:
Pulmonary pharmacology & therapeutics, 12(3), 185-192. Academic Press Inc.
Interactions of formoterol and theophylline were evaluated with the use of pharmacokinetic-pharmacodynamic (PK/PD) modelling. Oral doses of 144 microg of formoterol and 375 mg of theophylline were given separately or combined to healthy subjects. As
Publikováno v:
Clinical pharmacokinetics. 22(3):231-237
The relationship between theophylline pharmacokinetics and its eosinopenic and hypokalaemic effects were studied in 6 healthy volunteers after an oral dose of theophylline 250 mg. The mean peak theophylline concentration (Cmax) of 8.33 +/- 2.16 mg/L
Publikováno v:
Pulmonary pharmacology, 5(1), 31-38. Academic Press Inc.
An integrated pharmacokinetic-pharmacodynamic model was used to quantify the β 2 -blocking activity of metoprolol in seven asthmatic patients. The patients received a subcutaneous dose of terbutaline on two consecutive days. On day 1 they were pretr
Publikováno v:
European journal of clinical pharmacology. 54(6)
Objective: To evaluate the effects of formoterol after oral administration on plasma eosinophils and plasma potassium in healthy subjects. Methods: Plasma concentrations of formoterol, peripheral eosinophil count and plasma potassium were determined
Publikováno v:
Clinical pharmacokinetics. 29(4)
Publikováno v:
European journal of clinical pharmacology, 49(1-2), 37-44. Springer Verlag
Changes in beta 2-adrenoceptor function by chronic dosing of beta 2-mimetics and the possible influence of a single dose of prednisone have been studied as changes over time in the concentration-effect relationship of the beta 2-adrenoceptor agonist
Publikováno v:
Therapeutic drug monitoring. 16(2)
A method for the assay of plasma concentrations of the long-acting beta 2-adrenoceptor agonist, formoterol is described. This method, in which high-performance liquid chromotography is used with electrochemical detection, enables, for the first time,
Publikováno v:
Clinical infectious diseases, 24(1), 77-78. Oxford University Press