Zobrazeno 1 - 10
of 21
pro vyhledávání: '"M. C. Marden"'
Publikováno v:
Biopolymers. 23:2587-2602
Tritium-exchange experiments were performed to assess the dynamics of the spectrin molecule. From the kinetics presented, spectrin appears as a fast-exchanging protein compared to globular proteins. This is easily explained by its known elongated str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c1bf63feba694296687dee431e11b38
https://doi.org/10.1002/bip.360231130
https://doi.org/10.1002/bip.360231130
Autor:
Sébastien Lacroix-Desmazes, Srini V. Kaveri, Sooryasarathi Dasgupta, Sandrine Delignat, Jordan D. Dimitrov, Ivan Peyron, Yohann Repessé, M. C. Marden, E. Farrokhi Moshai, L. Kiger
Publikováno v:
Journal of thrombosis and haemostasis : JTH. 10(6)
Summary. Background: Heme is a redox active macrocyclic compound that is released upon tissue damage or hemorrhages. The extracellular release of large amounts of heme saturates scavenging heme-binding proteins. Free heme has been proposed to affect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::899065592fcba37d2f31b416b0eb8ef1
https://pubmed.ncbi.nlm.nih.gov/22471307
https://pubmed.ncbi.nlm.nih.gov/22471307
Autor:
Icko E T Iben, Lou Reinisch, Pál Ormos, Stan Luck, Robert D. Young, Larry B. Sorensen, Aihua Xie, B. R. Cowen, Hans Frauenfelder, J. Bruce Johnson, M. K. Hong, E. Shyamsunder, Reinhard Scholl, Alfons Schulte, Kwok To Yue, M. C. Marden, Neil A. Alberding, Anjum Ansari, D. Braunstein, Peter J. Steinbach, J. R. Mourant
Publikováno v:
The Journal of Physical Chemistry. 94:1024-1037
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f9dd148f975c5e23506d192484c9bcd
https://doi.org/10.1021/j100366a002
https://doi.org/10.1021/j100366a002
Autor:
E, Bissé, N, Zorn, I, Heinrichs, A, Eigel, A, Van Dorsselaer, H, Wieland, J, Kister, M C, Marden
Publikováno v:
The Journal of biological chemistry. 275(28)
A new abnormal hemoglobin was detected in a young German anemic patient by cation-exchange high performance liquid chromatography (HPLC). Using a combination of electrospray mass spectrometry, HPLC, direct sequencing, and family screening with polyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::659be7350d0ee41a92ffb0ef5367b74e
https://pubmed.ncbi.nlm.nih.gov/10770934
https://pubmed.ncbi.nlm.nih.gov/10770934
Autor:
I, Papassotiriou, J, Kister, N, Griffon, A, Stamoulakatou, D J, Abraham, M C, Marden, D, Loukopoulos, C, Poyart
Publikováno v:
British journal of haematology. 102(5)
Improving the delivery of oxygen to the tissues by decreasing the oxygen affinity of haemoglobin has been a major aim of several laboratories over recent years because this may reduce the consequences of anaemia and/or improve tissue oxygenation in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1393a5bf98cabc84dc3b94806e126fec
https://pubmed.ncbi.nlm.nih.gov/9753039
https://pubmed.ncbi.nlm.nih.gov/9753039
Autor:
I, Papassotiriou, J, Kister, N, Griffon, D J, Abraham, E, Kanavakis, J, Traeger-Synodinos, A, Stamoulakatou, M C, Marden, C, Poyart
Publikováno v:
Experimental hematology. 26(10)
Patients with the nondeletion genotype of hemoglobinopathy H (HbH or beta4) disease have higher proportions of HbH and more severe tissue hypoxia than patients with the deletion genotype. Because these patients' red blood cells (RBCs) contain mainly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::928687acf21c3f0d4c9a38817fbc7b2d
https://pubmed.ncbi.nlm.nih.gov/9728926
https://pubmed.ncbi.nlm.nih.gov/9728926
Autor:
A, Dumoulin, L, Kiger, N, Griffon, C, Vasseur, I, Kister, P, Génin, M C, Marden, J, Pagnier, C, Poyart
Publikováno v:
Protein science : a publication of the Protein Society. 5(1)
Based on the properties of two low oxygen affinity mutated hemoglobins (Hb), we have engineered a double mutant Hb (rHb beta YD) in which the beta F41Y substitution is associated with K82D. Functional studies have shown that the Hb alpha 2 beta 2(C7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::55b87fd004016ffd2a1793648433cbe2
https://pubmed.ncbi.nlm.nih.gov/8771203
https://pubmed.ncbi.nlm.nih.gov/8771203
Autor:
A, Dumoulin, L, Kiger, R, Jiang, V, Baudin, C, Vasseur, S G, Sligar, M C, Marden, J, Pagnier, C, Poyart
Publikováno v:
FEBS letters. 374(1)
In the stereochemical model proposed by Perutz [1], the Fe-His(F8) bond plays a significant role in the allosteric transition in hemoglobin and the resulting cooperativity in ligand binding. When this bond is ruptured, there is a loss in the transmis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba1ab96a1af0cafdfb130e14573d0e4a
https://pubmed.ncbi.nlm.nih.gov/7589508
https://pubmed.ncbi.nlm.nih.gov/7589508
We have tried to find out why Ascaris hemoglobin has such an exceptionally high oxygen affinity (P50 approximately 0.004 mmHg; 1 mmHg = 133 Pa). Following Kloek et al., we have synthesized the N-terminal globin domain of Ascaris hemoglobin in Escheri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::603ae08b769566cc142ee151613aa712
https://europepmc.org/articles/PMC43206/
https://europepmc.org/articles/PMC43206/
Publikováno v:
Methods in enzymology. 232
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0325325319b23101733181e90ea29bc4
https://pubmed.ncbi.nlm.nih.gov/8057886
https://pubmed.ncbi.nlm.nih.gov/8057886