Zobrazeno 1 - 10
of 16
pro vyhledávání: '"M. C. M. Macintosh"'
Publikováno v:
Prenatal Diagnosis. 17:401-405
Initial studies at 17-22 weeks' gestation evaluating urinary beta-core human chorionic gonadotrophin (hCG) as a marker for Down's syndrome had suggested that it may have more potential than its serum counterpart. This study measured maternal urinary
Autor:
J. Hansen, C. Lundsteen, T. Chard, Nicholas J. Wald, M. C. M. Macintosh, Margareta Mikkelsen, G. B. Petersen, A. J. Therkelsen
Publikováno v:
BJOG: An International Journal of Obstetrics and Gynaecology. 102:798-801
Objective To estimate the fetal loss of Down's syndrome fetuses between the time of chorionic villus sampling (10 weeks gestation) and the time of amniocentesis (16 weeks gestation) and term in women aged 35 years and older. Design The age specific p
Publikováno v:
Prenatal Diagnosis. 15:691-694
This study examined the effect of estimation of gestational age from the menstrual history compared with that from crown-rump length (CRL) measurement on the detection rate of screening for aneuploidies in the first trimester. Pregnancy-associated pl
Autor:
Tim Chard, M. C. M. Macintosh
Publikováno v:
jpme. 23:421-436
Down's syndrome (DS) is the commonest cause of severe mental retardation in children. It is the result of trisomy of chromosome 21 which is usually a random event though it is commoner in older mothers. DS can be diagnosed by chorionic villus samplin
Publikováno v:
BJOG: An International Journal of Obstetrics and Gynaecology. 100:1076-1081
Publikováno v:
Prenatal Diagnosis. 13:563-568
The relationship between first-trimester maternal serum Schwangerschafts protein 1 (SP1) and the karyotype of the pregnancy was examined in 692 women who underwent chorionic villus biopsy at 6-12 weeks. There were 30 pregnancies with abnormal karyoty
Publikováno v:
Methods of Information in Medicine. 32:175-179
The analysis of the clinical efficiency of a biochemical parameter in the prediction of chromosome anomalies is described, using a database of 475 cases including 30 abnormalities. A comparison was made of two different approaches to the statistical
Autor:
J.G. Grudzinskas, M. C. M. Macintosh, L. Tului, A. Lanzani, T. Chard, K. Shrimanker, S.D. Maguiness, B. Teisner, I. Bonacchi, Bruno Brambati
Publikováno v:
BJOG: An International Journal of Obstetrics & Gynaecology. 100:324-326
Objective To assess the relation between maternal serum pregnancy associated plasma protein A (PAPP-A) in the first trimester and the outcome of pregnancy by karyotype. Design A retrospective study of PAPP-A levels in blood samples collected prior to
Autor:
M. C. M. Macintosh, Tim Chard
Publikováno v:
Medical education. 31(3)
SUMMARY The use of pelvic trainers in undergraduate teaching was evaluated, using a questionnaire based on examination findings of a series of four pelvic trainers by 20 medical students and 34 gynaecologists. The main outcome measures were the abili
Autor:
Tim Chard, F. Muller, Børge Teisner, M. C. M. Macintosh, Kiran Sharma, Ray K. Iles, R. H. T. Ward, J. G. Grudzinskas
Publikováno v:
Scopus-Elsevier
Maternal serum levels of human chorionic gonadotrophin and its subunits (intact, alpha, and free beta h CG) and pregnancy-associated plasma protein A (PAPP-A) were measured in 279 women between 8 and 14 weeks' gestation. This group included 23 pregna