Výsledky vyhledávání - "M. C. Glassy"

A human natural antibody to adenocarcinoma that inhibits tumour cell migration

Autor: M. C. Glassy, Norio Saito, J. Yasutomi, N. Nakajima, M. E. Mcknight, Keiji Koda

Publikováno v: British Journal of Cancer

We characterized a natural human antibody to adenocarcinomas and investigated the biological role of this Ab/Ag complex in cancer expansion. Human monoclonal antibodies (HuMAbs) were generated with hybridoma fusion methods using regional nodal lympho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a667078c6cd817204c160f7bc8cbda
http://europepmc.org/articles/PMC2063195

Zobrazit plný text záznamu

Immunotherapy for recurrent colorectal cancers with human monoclonal antibody SK-1

Autor: K, Koda, M C, Glassy, M E, McKnight, J, Yasutomi, N, Saito, M, Dan, N, Nakajima

Publikováno v: Anticancer research. 21(1B)

The human monoclonal antibody SK-1 recognizes a glycoprotein expressed on the majority of colon cancer tissues. In the current study, we evaluated the safety, toxicity and preliminary efficacy of escalating dosages of SK-1 in patients with advanced c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::795acd64758740914f0095615376d7b3
https://pubmed.ncbi.nlm.nih.gov/11299816

Zobrazit plný text záznamu

Identification of the immunoreactive peptide sequence for AgSK1, an adenocarcinoma-restricted antigen

Autor: J, Yasutomi, K, Koda, N, Saito, N, Nakajima, M, Nasoff, M, McKnight, S, Mukerjee, C, Gaskins, P C, Chau, M C, Glassy

Publikováno v: Tissue antigens. 55(2)

SK1, a human immunoglobulin M (IgM) monoclonal antibody was derived from regional nodal lymphocytes of a Dukes B colon carcinoma patient. The antigen recognized by the human monoclonal antibody (HuMab) SK1, termed AgSK1, was shown to be a two-chain g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5814368d22dfa4dd692ec138b3de9a70
https://pubmed.ncbi.nlm.nih.gov/10746788

Zobrazit plný text záznamu

Co-expression of tumor antigens and their modulation by pleiotrophic modifiers enhance targeting of human monoclonal antibodies to pancreatic carcinoma

Autor: S, Mukerjee, M E, McKnight, M, Nasoff, M C, Glassy

Publikováno v: Human antibodies. 9(1)

Cocktails of human monoclonal antibodies (HuMAbs) have been used to increase the likelihood of identifying heterogeneous cancer cells. We utilized 3 HuMAbs termed SK-1, GM4, and GMA1, which recognized a 42-46 kDa two chain structure, a 57 kDa antigen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::623f1a4342c3b9ac3167ce09ffbb17ad
https://pubmed.ncbi.nlm.nih.gov/10331182

Zobrazit plný text záznamu

Production methods for generating human monoclonal antibodies

Autor: M C, Glassy

Publikováno v: Human antibodies and hybridomas. 4(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5c3afbab747cb18f72219ef0fa6497c3
https://pubmed.ncbi.nlm.nih.gov/8257769

Zobrazit plný text záznamu

Use of severe combined immunodeficient (SCID) mice to produce human hybridoma ascites

Autor: M E, McKnight, K, Prather, K, Koda, K F, DeBoer, M C, Glassy

Publikováno v: Human antibodies and hybridomas. 2(4)

The use of the severe combined immunodeficient mouse (SCID), CB-17/Icr//Imd-SCID, was investigated for the production of human hybridoma ascites containing human antibody. Human-human hybridomas, generated from the fusion of lymphocytes isolated from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::300c43b8cb890b2df7abd1d75d41f80b
https://pubmed.ncbi.nlm.nih.gov/1751782

Zobrazit plný text záznamu

Human monoclonal antibodies to nuclear antigens

Autor: M E, McKnight, K, Koda, K, DeBoer, M C, Glassy

Publikováno v: Human antibodies and hybridomas. 1(2)

Human lymph node lymphocytes from cancer patients were fused with either the UC 729-6 or SHFP-1 human fusion partners. Resulting human-human hybridomas were tetraploid, expressed markers from both parent cells, and secreted approximately 1 microgram

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::333a674f6041930a596571b4902949d9
https://pubmed.ncbi.nlm.nih.gov/2103355

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání