Myelopoietic competence of stroma composed of hepatic granuloma-derived connective tissue cells or skin fibroblasts

Autor: M, Alvarez-Silva, A C, Pinazo, M C, el-Cheikh, R, Borojevic

Publikováno v: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. 27(9)

1. Connective tissue cells isolated from hepatic granulomas (GR cells), induced in mouse liver tissue by schistosomal infection, are able to sustain myelopoiesis, while other connective tissue cells such as skin fibroblasts (SF) are not. 2. We compar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::67d9b6de5ca08e3c821253ecba5c499d
https://pubmed.ncbi.nlm.nih.gov/7787797

Experimental murine schistosomiasis mansoni: hyperplasia of the mono-macrophage cell lineage and stimulation of myeloid proliferation by peripheral macrophages

Autor: R, Borojevic, C G, Pinto, M C, el-Cheikh, H S, Dutra

Publikováno v: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. 22(5)

1. Normal and schistosome-infected mice were similar in terms of the total number of bone marrow myeloid cell precursors and their proliferative capacity in vitro when stimulated with supernatants of L-929 cells containing M-CSF. 2. Delayed different

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a0ad68c28e1f30eb11488d8950a9a808
https://pubmed.ncbi.nlm.nih.gov/2515904

Increase of B-lymphocyte number and activity during experimental murine schistosomiasis mansoni

Autor: M C, el-Cheikh, H S, Dutra, P, Minóprio, R, Borojevic

Publikováno v: Europe PubMed Central

1. In schistosomal infection, the hyperergic acute phase of the disease evolves progressively into the chronic one, with establishment of a relative equilibrium between the parasites and the corresponding host responses. This down-regulation of host

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::cc3c2d73a4cf6aec6c54f786918e8ea1
http://europepmc.org/abstract/med/7874027

Design and Synthesis of Dual Galectin-3 and EGFR Inhibitors Against Liver Fibrosis.

Autor: Liu S; School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, China.; Henan Polysaccharide Research Center, Henan Key Laboratory of Chinese Medicine for Polysaccharides and Drugs Research, Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, China.; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Science, SSIP Healthcare and Medicine Demonstration Zone, Zhongshan, Guangdong, Tsuihang New District, 528400, China., He F; Glycochemistry and Glycobiology Lab, CAS Key Laboratory of Receptor Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China.; University of Chinese Academy of Science, No.19 A Yuquan Road, Beijing, 100049, China., Jin C; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Science, SSIP Healthcare and Medicine Demonstration Zone, Zhongshan, Guangdong, Tsuihang New District, 528400, China.; Glycochemistry and Glycobiology Lab, CAS Key Laboratory of Receptor Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China.; University of Chinese Academy of Science, No.19 A Yuquan Road, Beijing, 100049, China., Li Q; Glycochemistry and Glycobiology Lab, CAS Key Laboratory of Receptor Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China.; University of Chinese Academy of Science, No.19 A Yuquan Road, Beijing, 100049, China.; School of Pharmacy, Henan University, Kaifeng, Henan, 475004, China., Zhao G; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Science, SSIP Healthcare and Medicine Demonstration Zone, Zhongshan, Guangdong, Tsuihang New District, 528400, China.; Glycochemistry and Glycobiology Lab, CAS Key Laboratory of Receptor Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China.; University of Chinese Academy of Science, No.19 A Yuquan Road, Beijing, 100049, China., Ding K; Henan Polysaccharide Research Center, Henan Key Laboratory of Chinese Medicine for Polysaccharides and Drugs Research, Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, China.; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Science, SSIP Healthcare and Medicine Demonstration Zone, Zhongshan, Guangdong, Tsuihang New District, 528400, China.; Glycochemistry and Glycobiology Lab, CAS Key Laboratory of Receptor Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China.; University of Chinese Academy of Science, No.19 A Yuquan Road, Beijing, 100049, China.

Publikováno v: Chemistry, an Asian journal [Chem Asian J] 2024 Nov 06, pp. e202401078. Date of Electronic Publication: 2024 Nov 06.

Lycopene inhibits hepatic stellate cell activation and modulates cellular lipid storage and signaling.

Autor: Elias, Monique de Barros, Oliveira, Felipe Leite, Guma, Fatima Costa Rodrigues, Martucci, Renata Brum, Borojevic, Radovan, Teodoro, Anderson Junger

Publikováno v: Food & Function; Apr2019, Vol. 10 Issue 4, p1974-1984, 11p