Výsledky vyhledávání - "M. Cândida Monteiro"

Study of the essentiality of the Aspergillus fumigatus triA gene, encoding RNA triphosphatase, using the heterokaryon rescue technique and the conditional gene expression driven by the alcA and niiA promoters

Autor: M. Cândida Monteiro, J. Ramón De Lucas

Publikováno v: Fungal Genetics and Biology. 47:66-79

The identification of essential genes represents a critical step in the discovery of novel therapeutic targets in Aspergillus fumigatus . Structural analyses of the Saccharomyces cerevisiae RNA triphosphatase pointed out this enzyme as an attractive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257bdaba10fcd6eaa6ad89e783d39a5f
https://doi.org/10.1016/j.fgb.2009.10.010

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Ability to grow on lipids accounts for the fully virulent phenotype in neutropenic mice of Aspergillus fumigatus null mutants in the key glyoxylate cycle enzymes

Autor: Fernando Laborda, Israel Olivas, Jose M. Minguez, M. Cândida Monteiro, Mar Royuela, Beatriz Romero, J. Ramón De Lucas

Publikováno v: Fungal Genetics and Biology. 45:45-60

Incidence and mortality rates of invasive aspergillosis clearly indicate the need of novel antifungals to treat patients suffering from this disease. Fungal proteins playing a crucial role in pathogenesis and with no orthologue in human cells are con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82e09ceed9d74a4a684175b20b5e779e
https://doi.org/10.1016/j.fgb.2007.05.002

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