Zobrazeno 1 - 10
of 359
pro vyhledávání: '"M. Brummett"'
Autor:
Lauriane Guichard, MD, Milo C. Engoren, MD, Yi-Ju Li, PhD, Matthew J. Sigakis, MD, Xinming An, PhD, Chad M. Brummett, MD, Matthew C. Mauck, MD, PhD, Karthik Raghunathan, MD, MPH, Daniel J. Clauw, MD, Vijay Krishnamoorthy, MD, PhD
Publikováno v:
Critical Care Explorations, Vol 6, Iss 11, p e1172 (2024)
IMPORTANCE:. In the ICU, opioids treat pain and improve ventilator tolerance as part of an analgosedation approach. Identifying predictors of opioid consumption during the ICU course might highlight actionable items to reduce opioid consumption. OBJE
Externí odkaz:
https://doaj.org/article/a9914fac53b04c729fefd9b87508a08e
Autor:
Mark C. Bicket, MD, PhD, Kao-Ping Chua, MD, PhD, Pooja Lagisetty, MD, MSc, Yi Li, PhD, Jennifer F. Waljee, MD, MPH, MS, Chad M. Brummett, MD, Thuy D. Nguyen, PhD, MPA
Publikováno v:
Annals of Surgery Open, Vol 5, Iss 2, p e421 (2024)
Externí odkaz:
https://doaj.org/article/4de4b28630f347a8a970ac619ae3c0f4
Autor:
Daniel B. Larach, Adam Lewis, Lisa Bastarache, Anita Pandit, Jing He, Anik Sinha, Nicholas J. Douville, Michael Heung, Michael R. Mathis, Jonathan D. Mosley, Jonathan P. Wanderer, Sachin Kheterpal, Matthew Zawistowski, Chad M. Brummett, Edward D. Siew, Cassianne Robinson-Cohen, Miklos D. Kertai
Publikováno v:
BMC Nephrology, Vol 23, Iss 1, Pp 1-11 (2022)
Abstract Background Prior studies support a genetic basis for postoperative acute kidney injury (AKI). We conducted a genome-wide association study (GWAS), assessed the clinical utility of a polygenic risk score (PRS), and estimated the heritable com
Externí odkaz:
https://doaj.org/article/813edc1012fa4c88a501d1fbf8d0c6be
Autor:
Maxwell Salvatore, Dylan Clark-Boucher, Lars G. Fritsche, Jacob Ortlieb, Janet Houghtby, Anisa Driscoll, Bryanne Caldwell-Larkins, Jennifer A. Smith, Chad M. Brummett, Sachin Kheterpal, Lynda Lisabeth, Bhramar Mukherjee
Publikováno v:
Epidemiology and Health, Vol 45 (2023)
The Epidemiologic Questionnaire (EPI-Q) was established to collect broad, uniform, self-reported health data to supplement electronic health record (EHR) and genotype information from participants in the University of Michigan (UM) Precision Health c
Externí odkaz:
https://doaj.org/article/f97da905cc2344679060f096546b1c8d
Autor:
Alex F. Peahl, MD, MSc, Alexander Hallway, BA, Brooke Kenney, MPH, Emma R. Lawrence, MD, MS, Roger Smith, MD, Chad M. Brummett, MD, Jennifer F. Waljee, MD, MPH, MS
Publikováno v:
AJOG Global Reports, Vol 3, Iss 3, Pp 100248- (2023)
Externí odkaz:
https://doaj.org/article/794947eeaa924eeaa5c46735e7d1d7da
Autor:
Matthew Zawistowski, Lars G. Fritsche, Anita Pandit, Brett Vanderwerff, Snehal Patil, Ellen M. Schmidt, Peter VandeHaar, Cristen J. Willer, Chad M. Brummett, Sachin Kheterpal, Xiang Zhou, Michael Boehnke, Gonçalo R. Abecasis, Sebastian Zöllner
Publikováno v:
Cell Genomics, Vol 3, Iss 2, Pp 100257- (2023)
Summary: Biobanks of linked clinical patient histories and biological samples are an efficient strategy to generate large cohorts for modern genetics research. Biobank recruitment varies by factors such as geographic catchment and sampling strategy,
Externí odkaz:
https://doaj.org/article/a1ae3f1dd1614819be1de45156e83e65
Publikováno v:
PLoS ONE, Vol 18, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/28b44d5545d649ea8b57faa8e7bdd732
Autor:
Adrien Georges, Min-Lee Yang, Takiy-Eddine Berrandou, Mark K. Bakker, Ozan Dikilitas, Soto Romuald Kiando, Lijiang Ma, Benjamin A. Satterfield, Sebanti Sengupta, Mengyao Yu, Jean-François Deleuze, Delia Dupré, Kristina L. Hunker, Sergiy Kyryachenko, Lu Liu, Ines Sayoud-Sadeg, Laurence Amar, Chad M. Brummett, Dawn M. Coleman, Valentina d’Escamard, Peter de Leeuw, Natalia Fendrikova-Mahlay, Daniella Kadian-Dodov, Jun Z. Li, Aurélien Lorthioir, Marco Pappaccogli, Aleksander Prejbisz, Witold Smigielski, James C. Stanley, Matthew Zawistowski, Xiang Zhou, Sebastian Zöllner, FEIRI investigators, International Stroke Genetics Consortium (ISGC) Intracranial Aneurysm Working Group, MEGASTROKE, Philippe Amouyel, Marc L. De Buyzere, Stéphanie Debette, Piotr Dobrowolski, Wojciech Drygas, Heather L. Gornik, Jeffrey W. Olin, Jerzy Piwonski, Ernst R. Rietzschel, Ynte M. Ruigrok, Miikka Vikkula, Ewa Warchol Celinska, Andrzej Januszewicz, Iftikhar J. Kullo, Michel Azizi, Xavier Jeunemaitre, Alexandre Persu, Jason C. Kovacic, Santhi K. Ganesh, Nabila Bouatia-Naji
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Fibromuscular dysplasia is a cardiovascular disease affecting mostly women with a mostly unknown genetic basis. Here the authors have performed a genome-wide association meta-analysis of Fibromuscular dysplasia to identify genetic loci, some of which
Externí odkaz:
https://doaj.org/article/1ca76cab0eb244289d31e35f5458c7b3
Autor:
Chad M. Brummett, Steven P. Cohen
The understanding of pain has undergone extraordinary development over the last 25 years. Half of all medical visits are initiated because of pain. The need for all clinicians and trainees to have a foundational knowledge of pain has become more crit
Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease
Autor:
Jonas B. Nielsen, Oren Rom, Ida Surakka, Sarah E. Graham, Wei Zhou, Tanmoy Roychowdhury, Lars G. Fritsche, Sarah A. Gagliano Taliun, Carlo Sidore, Yuhao Liu, Maiken E. Gabrielsen, Anne Heidi Skogholt, Brooke Wolford, William Overton, Ying Zhao, Jin Chen, He Zhang, Whitney E. Hornsby, Akua Acheampong, Austen Grooms, Amanda Schaefer, Gregory J. M. Zajac, Luis Villacorta, Jifeng Zhang, Ben Brumpton, Mari Løset, Vivek Rai, Pia R. Lundegaard, Morten S. Olesen, Kent D. Taylor, Nicholette D. Palmer, Yii-Der Chen, Seung H. Choi, Steven A. Lubitz, Patrick T. Ellinor, Kathleen C. Barnes, Michelle Daya, Nicholas Rafaels, Scott T. Weiss, Jessica Lasky-Su, Russell P. Tracy, Ramachandran S. Vasan, L. Adrienne Cupples, Rasika A. Mathias, Lisa R. Yanek, Lewis C. Becker, Patricia A. Peyser, Lawrence F. Bielak, Jennifer A. Smith, Stella Aslibekyan, Bertha A. Hidalgo, Donna K. Arnett, Marguerite R. Irvin, James G. Wilson, Solomon K. Musani, Adolfo Correa, Stephen S. Rich, Xiuqing Guo, Jerome I. Rotter, Barbara A. Konkle, Jill M. Johnsen, Allison E. Ashley-Koch, Marilyn J. Telen, Vivien A. Sheehan, John Blangero, Joanne E. Curran, Juan M. Peralta, Courtney Montgomery, Wayne H-H Sheu, Ren-Hua Chung, Karen Schwander, Seyed M. Nouraie, Victor R. Gordeuk, Yingze Zhang, Charles Kooperberg, Alexander P. Reiner, Rebecca D. Jackson, Eugene R. Bleecker, Deborah A. Meyers, Xingnan Li, Sayantan Das, Ketian Yu, Jonathon LeFaive, Albert Smith, Tom Blackwell, Daniel Taliun, Sebastian Zollner, Lukas Forer, Sebastian Schoenherr, Christian Fuchsberger, Anita Pandit, Matthew Zawistowski, Sachin Kheterpal, Chad M. Brummett, Pradeep Natarajan, David Schlessinger, Seunggeun Lee, Hyun Min Kang, Francesco Cucca, Oddgeir L. Holmen, Bjørn O. Åsvold, Michael Boehnke, Sekar Kathiresan, Goncalo R. Abecasis, Y. Eugene Chen, Cristen J. Willer, Kristian Hveem
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Drugs targeting cardiovascular disease (CVD) can have negative consequences for liver function. Here, the authors combine genome wide analyses on 69,479 individuals to identify loss-of-function variants with beneficial effects on CVD-related traits w
Externí odkaz:
https://doaj.org/article/2eecf9230b454b46b95b45b0f20ddd2e