Zobrazeno 1 - 10
of 372
pro vyhledávání: '"M. Boyett"'
Autor:
Jinzhou Yuan, Hanna Mendes Levitin, Veronique Frattini, Erin C. Bush, Deborah M. Boyett, Jorge Samanamud, Michele Ceccarelli, Athanassios Dovas, George Zanazzi, Peter Canoll, Jeffrey N. Bruce, Anna Lasorella, Antonio Iavarone, Peter A. Sims
Publikováno v:
Genome Medicine, Vol 10, Iss 1, Pp 1-15 (2018)
Abstract Background Despite extensive molecular characterization, we lack a comprehensive understanding of lineage identity, differentiation, and proliferation in high-grade gliomas (HGGs). Methods We sampled the cellular milieu of HGGs by profiling
Externí odkaz:
https://doaj.org/article/6be843e71c994480a656cf91533de3d3
Autor:
Tom Curran, Richard J. Gilbertson, James M. Boyett, Naoko Takebe, Dana Wallace, Murali Chintagumpala, Stewart Goldman, Roger J. Packer, Larry E. Kun, Sue Kaste, David W. Ellison, Clinton F. Stewart, Amar Gajjar
Purpose: To investigate the safety, dose-limiting toxicities, and pharmacokinetics of the smoothened inhibitor vismodegib in children with refractory or relapsed medulloblastoma.Experimental design: Initially, vismodegib was administered daily at 85
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::044aeb59b1dd16c65d049e326fb982ea
https://doi.org/10.1158/1078-0432.c.6522327
https://doi.org/10.1158/1078-0432.c.6522327
Autor:
Tom Curran, Richard J. Gilbertson, James M. Boyett, Naoko Takebe, Dana Wallace, Murali Chintagumpala, Stewart Goldman, Roger J. Packer, Larry E. Kun, Sue Kaste, David W. Ellison, Clinton F. Stewart, Amar Gajjar
PDF file - 156K, Supplementary Fig. S1. Concentration-time plots of the first 72 hours after administration of the first vismodegib dose during Course 1 to the patients in the initial cohort: 6 received 85 mg/m2 (Figure A & B), and 7 received 170 mg/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26899133026bacfbf4bfddf5759a4122
https://doi.org/10.1158/1078-0432.22451901
https://doi.org/10.1158/1078-0432.22451901
Autor:
Tom Curran, Richard J. Gilbertson, James M. Boyett, Naoko Takebe, Dana Wallace, Murali Chintagumpala, Stewart Goldman, Roger J. Packer, Larry E. Kun, Sue Kaste, David W. Ellison, Clinton F. Stewart, Amar Gajjar
PDF file - 104K, Supplementary Table S1. Vismodegib Dosing Strategy Supplementary Table S2. Commonly Reported Adverse Events According to Grade Supplementary Table S3. Pharmacokinetics of Unbound Vismodegib in Pediatric Patients with Medulloblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1065899e0687d584c3cca4ce9b81772f
https://doi.org/10.1158/1078-0432.22451898.v1
https://doi.org/10.1158/1078-0432.22451898.v1
Autor:
Eleonora F Spinazzi, Michael G Argenziano, Pavan S Upadhyayula, Matei A Banu, Justin A Neira, Dominique M O Higgins, Peter B Wu, Brianna Pereira, Aayushi Mahajan, Nelson Humala, Osama Al-Dalahmah, Wenting Zhao, Akshay V Save, Brian J A Gill, Deborah M Boyett, Tamara Marie, Julia L Furnari, Tejaswi D Sudhakar, Sylwia A Stopka, Michael S Regan, Vanessa Catania, Laura Good, Stergios Zacharoulis, Meenu Behl, Petros Petridis, Sachin Jambawalikar, Akiva Mintz, Angela Lignelli, Nathalie Y R Agar, Peter A Sims, Mary R Welch, Andrew B Lassman, Fabio M Iwamoto, Randy S D’Amico, Jack Grinband, Peter Canoll, Jeffrey N Bruce
Publikováno v:
Lancet Oncol
Topotecan is cytotoxic to glioma cells but is clinically ineffective because of drug delivery limitations. Systemic delivery is limited by toxicity and insufficient brain penetrance, and, to date, convection-enhanced delivery (CED) has been restricte
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Kirstie M. Boyett, Katie Constantin
Publikováno v:
Victims & Offenders. 16:869-892
According to general strain theory (GST), individuals engage in deviant behavior to reduce feelings of negative affect that occur because of strain. In this paper, we examine the relationship betwe...
Autor:
Eleonora F. Spinazzi, Michael G. Argenziano, Pavan S. Upadhyayula, Matei A. Banu, Justin A. Neira, Dominique M.O. Higgins, Peter B. Wu, Brianna Pereira, Aayushi Mahajan, Nelson Humala, Osama Al-Dalahmah, Wenting Zhao, Akshay V. Save, Deborah M. Boyett, Tamara Marie, Julia L Furnari, Tejaswi D. Sudhakar, Sylwia A. Stopka, Michael S. Regan, Vanessa Catania, Laura Good, Meenu Behl, Sachin Jambawalikar, Akiva Mintz, Angela Lignelli, Nathalie Y.R. Agar, Peter A. Sims, Mary Welch, Andrew Lassman, Fabio Iwamoto, Randy S. D’Amico, Jack Grinband, Peter Canoll, Jeffrey N. Bruce
Glioblastoma, the most common primary brain malignancy, is invariably fatal. Systemic chemotherapy is ineffective mostly because of drug delivery limitations. To overcome this, we devised an internalized pump-catheter system for direct chronic convec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e662be7b4518bea92e47e3dde561c23f
https://doi.org/10.1101/2021.12.04.21266935
https://doi.org/10.1101/2021.12.04.21266935
Autor:
Sarah Leary, Girish Dhall, Shannon M. MacDonald, Aashim Bhatia, James M. Boyett, Maryam Fouladi, Shengjie Wu, Amar Gajjar, Jason Fangusaro, Mark M. Souweidane, Soumen Khatua, Sunita K. Patel, Erin S Murphy, Ute Bartels, Leanne Embry, Christine L. Trask, Dennis Shaw, Arzu Onar-Thomas
Publikováno v:
Neuro Oncol
Background The study aimed to evaluate whether simplified chemotherapy followed by dose-reduced irradiation was effective for treating patients (ages 3–21 years) with localized germinoma. The primary endpoint was 3-year progression-free survival (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6af0e4003d9b5b20d143e336fc32953
https://europepmc.org/articles/PMC9159444/
https://europepmc.org/articles/PMC9159444/
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.