Zobrazeno 1 - 10 of 41 pro vyhledávání: '"M. Biollaz"'
1
CGP 53153: a new potent inhibitor of 5alpha-reductase
Autor: Ch. Batzl, E. Scheidegger, Ajay S. Bhatnagar, A. Häusler, P.R. Allegrini, M. Biollaz
Publikováno v: The Journal of steroid biochemistry and molecular biology. 57(3-4)
CGP 53153 (N-2-(cyano-2-propyl)-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carb oxamide) is a steroidal inhibitor of 5alpha-reductase, the enzyme which effects the conversion of testosterone (T) to 5alpha-dihydrotestosterone (DHT). In vitro, CGP 53153 c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b982d7a7f2ac1746b960ee2d05ca852a
https://pubmed.ncbi.nlm.nih.gov/8645628
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3
Characterization of the Renal and Hormonal Effects of Three Novel Anti-Mineralocorticoids in Vitro and in Vivo
Autor: Jürgen Grob, M. Biollaz, C. Kraehenbuehl, H. Haenni, L. Schenkel, U. Joss, M. de Gasparo, S. Whitebread, H. P. Ramjoue
Publikováno v: Diuretics: Basic, Pharmacological, and Clinical Aspects ISBN: 9781461292272
Antimineralocorticoid compounds are widely prescribed for the treatment of essential hypertension and primary or secondary hyper-aldosteronism. Spironolactone is the most commonly used drug of this type. Its administration however is limited by its a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7ffcc30ee4d92c3140a1dfb923da2d46
https://doi.org/10.1007/978-1-4613-2067-8_141
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7
Three new epoxy-spirolactone derivatives: characterization in vivo and in vitro
Autor: M, de Gasparo, U, Joss, H P, Ramjoué, S E, Whitebread, H, Haenni, L, Schenkel, C, Kraehenbuehl, M, Biollaz, J, Grob, J, Schmidlin
Publikováno v: The Journal of pharmacology and experimental therapeutics. 240(2)
The use of spironolactone, the most commonly used antimineralocorticoid compound, is limited by the occurrence of sexual endocrine effects. New antagonists are therefore required which lack these unwanted effects. Three 9 alpha,11 alpha-epoxy-derivat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6c136a22b8c46a86fd306eba82738dc7
https://pubmed.ncbi.nlm.nih.gov/2949071
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9
ChemInform Abstract: EINE ZWEISTUFEN-SYNTH. VON PREGNAN- UND CORTICOIDEN SEITENKETTEN
Autor: M. Biollaz, W. Haefliger, J. H. Fried, P. Crabbe, Esperanza Velarde
Publikováno v: Chemischer Informationsdienst. 3
Das Athinyl-Derivat (I) reagiert mit Zinkstaub in siedendem Diglyme zum Allen (II) (86% Ausbeute), das durch Umsetzung mit Osmiumtetroxid/Pyridin in Benzol und anschliesend mit Natriumsulfit/Kaliumbicarbonat in das Dihydroxy-keto-Steroid (III) uberge
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b2ed3b4a136e1a90affa8568447e3750
https://doi.org/10.1002/chin.197207328
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10
17-Alpha-propadienyl-19-nortestosterone and related compounds. A new series of potent orally active progestogens
Autor: Wendell H. Rooks, P. Crabbe, R. M. Landeros, J. H. Fried, M. Biollaz, J. A. Edwards, L. Cuellar
Publikováno v: Journal of medicinal chemistry. 14(12)
The synthesis of several 17alpha-propadienyl of 18-methyl propadiene and of 17alpha allene steroids in the 19-nortestosterone and estradiol series is described. Of 2 methods described reduction of the monotetrahydropyranyloxy ether with lithium alumi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56700ae6cff58bcfc4afe97035dd80c5
https://pubmed.ncbi.nlm.nih.gov/5116232
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