Zobrazeno 1 - 10
of 122
pro vyhledávání: '"M. Bielski"'
Autor:
Ezra Y. Rosen, Helen H. Won, Youyun Zheng, Emiliano Cocco, Duygu Selcuklu, Yixiao Gong, Noah D. Friedman, Ino de Bruijn, Onur Sumer, Craig M. Bielski, Casey Savin, Caitlin Bourque, Christina Falcon, Nikeysha Clarke, Xiaohong Jing, Fanli Meng, Catherine Zimel, Sophie Shifman, Srusthi Kittane, Fan Wu, Marc Ladanyi, Kevin Ebata, Jennifer Kherani, Barbara J. Brandhuber, James Fagin, Eric J. Sherman, Natasha Rekhtman, Michael F. Berger, Maurizio Scaltriti, David M. Hyman, Barry S. Taylor, Alexander Drilon
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
The results of the phase 1/2 LIBRETTO-001 clinical trial has recently established the efficacy of the RET inhibitor selpercatinib in RET-driven cancers. Here, the authors characterize the molecular determinants of response and resistance in 72 LIBRET
Externí odkaz:
https://doaj.org/article/c9aadc1f6bbc44acba731c2a7dcb7aef
Autor:
Craig M. Bielski, Barry S. Taylor
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-3 (2021)
While genomic instability is a hallmark of cancer, its genetic vulnerabilities remain poorly understood. Identifying strategies that exploit genomic instability to selectively target cancer cells is a central challenge in cancer biology with major im
Externí odkaz:
https://doaj.org/article/05aa6b75dc3d45a196bcacb216f9a997
Autor:
Ezra Y. Rosen, Helen H. Won, Youyun Zheng, Emiliano Cocco, Duygu Selcuklu, Yixiao Gong, Noah D. Friedman, Ino de Bruijn, Onur Sumer, Craig M. Bielski, Casey Savin, Caitlin Bourque, Christina Falcon, Nikeysha Clarke, Xiaohong Jing, Fanli Meng, Catherine Zimel, Sophie Shifman, Srushti Kittane, Fan Wu, Marc Ladanyi, Kevin Ebata, Jennifer Kherani, Barbara J. Brandhuber, James Fagin, Eric J. Sherman, Natasha Rekhtman, Michael F. Berger, Maurizio Scaltriti, David M. Hyman, Barry S. Taylor, Alexander Drilon
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/5da51ab03db947f7a3ffd0a6118bb43a
Autor:
Barbara Oldrini, Wan-Ying Hsieh, Hediye Erdjument-Bromage, Paolo Codega, Maria Stella Carro, Alvaro Curiel-García, Carl Campos, Maryam Pourmaleki, Christian Grommes, Igor Vivanco, Daniel Rohle, Craig M. Bielski, Barry S. Taylor, Travis J. Hollmann, Marc Rosenblum, Paul Tempst, John Blenis, Massimo Squatrito, Ingo K. Mellinghoff
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
The epidermal growth factor receptor (EGFR) signalling is regulated at multiple levels. Here the authors show that the importin RanBP6 acts as a tumor suppressor in Glioblastoma and regulates EGFR signalling through promoting translocation of STAT3 t
Externí odkaz:
https://doaj.org/article/015fa09cb6784ac18a7db7bbdca85e1c
Publikováno v:
Psychology in the Schools.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db33a8a3c299843be9acb9d9189a9287
https://doi.org/10.1002/pits.22940
https://doi.org/10.1002/pits.22940
Autor:
Barry S. Taylor, David M. Hyman, David B. Solit, Neal Rosen, Michael F. Berger, José Baselga, Nikolaus Schultz, Marc Ladanyi, Sarat Chandarlapaty, Maria E. Arcila, Ryma Benayed, Ahmet Zehir, Gowtham Jayakumaran, Nicholas D. Socci, Dalicia N. Reales, Bob T. Li, Pedram Razavi, Ritika Kundra, Selcuk Onur Sumer, JianJiong Gao, Christopher Harris, Swati Patel, Tambudzai Shamu, Alexander Gorelick, Alexander Penson, Cyriac Kandoth, Sarah Phillips, Debyani Chakravarty, Philip Jonsson, Mark T.A. Donoghue, Craig M. Bielski, Alison M. Schram, Tripti Shrestha Bhattarai, Matthew T. Chang
Supplementary Figures 1-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36f2bb175ec9a267a2689e9945e1683a
https://doi.org/10.1158/2159-8290.22532158.v1
https://doi.org/10.1158/2159-8290.22532158.v1
Autor:
Barry S. Taylor, David M. Hyman, David B. Solit, Neal Rosen, Michael F. Berger, José Baselga, Nikolaus Schultz, Marc Ladanyi, Sarat Chandarlapaty, Maria E. Arcila, Ryma Benayed, Ahmet Zehir, Gowtham Jayakumaran, Nicholas D. Socci, Dalicia N. Reales, Bob T. Li, Pedram Razavi, Ritika Kundra, Selcuk Onur Sumer, JianJiong Gao, Christopher Harris, Swati Patel, Tambudzai Shamu, Alexander Gorelick, Alexander Penson, Cyriac Kandoth, Sarah Phillips, Debyani Chakravarty, Philip Jonsson, Mark T.A. Donoghue, Craig M. Bielski, Alison M. Schram, Tripti Shrestha Bhattarai, Matthew T. Chang
Supplementary Tables 1-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4544871eb1f0f77f3d4727637819dfe2
https://doi.org/10.1158/2159-8290.22532155
https://doi.org/10.1158/2159-8290.22532155
Autor:
Christine A. Iacobuzio-Donahue, Barry S. Taylor, Nicholas D. Socci, Martin A. Nowak, Ralph H. Hruban, Laura D. Wood, Eileen M. O'Reilly, Debyani Chakravarty, Mithat Gönen, Alexander V. Penson, Craig M. Bielski, Alexander Heyde, Johannes G. Reiter, Jerry P. Melchor, Lance Zhang, Rajya Kappagantula, Jungeui Hong, Akimasa Hayashi, Alvin P. Makohon-Moore, Jeffrey M. Gerold, Marc A. Attiyeh, Hitomi Sakamoto
Figures S1-S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b20b9f9455c55ab9c9d3787b7aadb2c5
https://doi.org/10.1158/2159-8290.22535195.v1
https://doi.org/10.1158/2159-8290.22535195.v1
Autor:
Christine A. Iacobuzio-Donahue, Barry S. Taylor, Nicholas D. Socci, Martin A. Nowak, Ralph H. Hruban, Laura D. Wood, Eileen M. O'Reilly, Debyani Chakravarty, Mithat Gönen, Alexander V. Penson, Craig M. Bielski, Alexander Heyde, Johannes G. Reiter, Jerry P. Melchor, Lance Zhang, Rajya Kappagantula, Jungeui Hong, Akimasa Hayashi, Alvin P. Makohon-Moore, Jeffrey M. Gerold, Marc A. Attiyeh, Hitomi Sakamoto
Supplemental Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199151f3e69542070ed2df494bce9bbb
https://doi.org/10.1158/2159-8290.22535192.v1
https://doi.org/10.1158/2159-8290.22535192.v1
Autor:
Christine A. Iacobuzio-Donahue, Suzanne L. Topalian, Barry S. Taylor, Timothy A. Chan, David B. Solit, Nicholas D. Socci, Rachel Karchin, Paul B. Chapman, Michael A. Postow, Nadeem Riaz, Vladimir Makarov, Zachary Kohutek, Rajya Kappagantula, Priscilla Baez, Collin Tokheim, Akimasa Hayashi, Craig M. Bielski, Jungeui Hong, Amanda Zucker, Jody E. Hooper, Evan J. Lipson, Alvin P. Makohon-Moore
Figure S6 shows phylogenies based on point mutations with UV signature mutations removed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f164bba3f3f32ada1a3f4bfbb99cc4
https://doi.org/10.1158/1078-0432.22479737
https://doi.org/10.1158/1078-0432.22479737