Zobrazeno 1 - 10
of 214
pro vyhledávání: '"M. Bidgood"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The Suppressor of Cytokine Signaling (SOCS) family proteins are important negative regulators of cytokine signaling. SOCS1 is the prototypical member of the SOCS family and functions in a classic negative-feedback loop to inhibit signaling in respons
Externí odkaz:
https://doaj.org/article/f1e2b2e01d894fef83112e58a14d5310
Autor:
Hao Chen, Nghi H. Nguyen, Charlene M. Magtoto, Simon A. Cobbold, Grace M. Bidgood, Lizeth G. Meza Guzman, Lachlan W. Richardson, Jason Corbin, Amanda E. Au, Bernhard C. Lechtenberg, Rebecca Feltham, Kate D. Sutherland, Christoph Grohmann, Sandra E. Nicholson, Brad E. Sleebs
Publikováno v:
Redox Biology, Vol 59, Iss , Pp 102552- (2023)
The Kelch-like ECH-associated protein 1 (KEAP1) - nuclear factor erythroid 2-related factor 2 (NRF2) signaling pathway senses reactive oxygen species and regulates cellular oxidative stress. Inhibiting KEAP1 to activate the NRF2 antioxidant response
Externí odkaz:
https://doaj.org/article/8bf601d4ee3e4a67b3cbbfafd936ded8
Autor:
Lizeth G Meza Guzman, Craig D Hyland, Grace M Bidgood, Evelyn Leong, Zihan Shen, Wilford Goh, Tobias Kratina, Jai Rautela, James E Vince, Sandra E Nicholson, Nicholas D Huntington
The clinical development of Natural Killer (NK) cell-mediated immunotherapy marks a milestone in the development of new cancer therapies and has gained traction due to the intrinsic ability of the NK cell to target and kill tumour cells. To fully har
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9288c96080d5dea0bc0340fa9048cce0
https://doi.org/10.1101/2023.04.17.537109
https://doi.org/10.1101/2023.04.17.537109
Autor:
Karen Doggett, Narelle Keating, Farhad Dehkhoda, Grace M. Bidgood, Evelyn Leong, Andrew Kueh, Nicos A. Nicola, Nadia J. Kershaw, Jeffrey J. Babon, Warren S. Alexander, Sandra E. Nicholson
Suppressor Of Cytokine Signaling (SOCS) 1 is a critical negative regulator of cytokine signaling and required to protect against an excessive inflammatory response. Genetic deletion ofSocs1results in unrestrained cytokine signaling and neonatal letha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcf366146a4af56198ad20f6a8376616
https://doi.org/10.1101/2022.12.20.521329
https://doi.org/10.1101/2022.12.20.521329
Autor:
Karen Doggett, Narelle Keating, Farhad Dehkhoda, Grace M. Bidgood, Lizeth G. Meza Guzman, Evelyn Leong, Andrew Kueh, Nicos A. Nicola, Nadia J. Kershaw, Jeffrey J. Babon, Warren S. Alexander, Sandra E. Nicholson
Publikováno v:
Cytokine. 165:156167
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35dacd35a714bc9babe6fde52ac85121
https://doi.org/10.1016/j.cyto.2023.156167
https://doi.org/10.1016/j.cyto.2023.156167
Autor:
Peter M. Bidgood, Andre Burger
Publikováno v:
55th AIAA Aerospace Sciences Meeting.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5009e6be429517eea787e2951ec7fe5c
https://doi.org/10.2514/6.2017-0774
https://doi.org/10.2514/6.2017-0774
Autor:
Peter M. Bidgood
Publikováno v:
55th AIAA Aerospace Sciences Meeting.
Proceedings of 55th AIAA Aerospace Sciences Meeting, Grapevine, Texas, USA, 9 - 13 January 2017
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d545325f5b7fcc73d9e618e6ae603635
https://doi.org/10.2514/6.2017-0106
https://doi.org/10.2514/6.2017-0106
Akademický článek
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Autor:
Martijn Fenaux, Stacey Eng, Stephanie A. Leavitt, Yu-Jen Lee, Eric M. Mabery, Yang Tian, Daniel Byun, Eda Canales, Michael O. Clarke, Edward Doerffler, Scott E. Lazerwith, Willard Lew, Qi Liu, Michael Mertzman, Philip Morganelli, Lianhong Xu, Hong Ye, Jennifer Zhang, Mike Matles, Bernard P. Murray, Judy Mwangi, Jingyu Zhang, Ahmad Hashash, Steve H. Krawczyk, Alison M. Bidgood, Todd C. Appleby, William J. Watkins
GS-9669 is a highly optimized thumb site II nonnucleoside inhibitor of the hepatitis C virus (HCV) RNA polymerase, with a binding affinity of 1.35 nM for the genotype (GT) 1b protein. It is a selective inhibitor of HCV RNA replication, with a mean 50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1d66793ecfe602fea0d21fe4a59c1e4
https://europepmc.org/articles/PMC3553741/
https://europepmc.org/articles/PMC3553741/
Autor:
P M Bidgood, FF Pieterse
Publikováno v:
51st AIAA Aerospace Sciences Meeting including the New Horizons Forum and Aerospace Exposition.
Alternative sensor technologies, materials, designs as well as manufacturing techniques are required to reduce lead times and meet future performance requirements. This paper outlines a design for a six-component internal wind tunnel balance incorpor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7e8c8726b612079d1d01613dd8521e2
https://doi.org/10.2514/6.2013-547
https://doi.org/10.2514/6.2013-547