Zobrazeno 1 - 10
of 15
pro vyhledávání: '"M. Bickett"'
Publikováno v:
Osteoarthritis and Cartilage. 20(11):1347-1356
Summary Objective Knowledge of mechanisms directing diarthrodial joint development may be useful in understanding joint pathologies and identifying new therapies. We have previously established that axolotl salamanders can fully repair large articula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd0d53dcb5612fda7997c9c6fe0babe3
Autor:
David M. Bickett, Francis X. Tavares, Pamela L. Golden, Lauren R. Sheckler, Stephen A. Thomson, Dulce Garrido, Andrew J. Peat, Pierette Banker, James E. Weiel, Steven M. Sparks, Scott Howard Dickerson, Daphne C. Clancy
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:981-985
Optimization of the amino acid residue of a series of anthranilimide-based glycogen phosphorylase inhibitors is described leading to the identification of serine and threonine ether analogs. t-Butylthreonine analog 20 displayed potent in vitro inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5159b246433fa9027e6bcec99dce7745
https://doi.org/10.1016/j.bmcl.2008.11.084
https://doi.org/10.1016/j.bmcl.2008.11.084
Autor:
Pierette Banker, Daphne C. Clancy, Francis X. Tavares, Pamela L. Golden, Liping Wang, James E. Weiel, Steven M. Sparks, Stephen A. Thomson, Lauren R. Sheckler, Dulce Garrido, Scott Howard Dickerson, Andrew J. Peat, David M. Bickett, H. Luke Carter, Kate A. Dwornik, Robert T. Nolte
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:976-980
Optimization of the amino acid residue within a series of anthranilimide-based glycogen phosphorylase inhibitors is described. These studies culminated in the identification of anthranilimides 16 and 22 which displayed potent in vitro inhibition of G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccab5b862050e9a20580b438b03c30f9
https://doi.org/10.1016/j.bmcl.2008.11.085
https://doi.org/10.1016/j.bmcl.2008.11.085
Publikováno v:
Journal of surgical education. 70(3)
Objective Student empowerment of curriculum changes is a double-edged sword. When examining our third-year surgery course every year, we debate where the line is between improving education through student input against allowing the students to desig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67c0c80fb2d1c5a5f02be98086f145d2
https://pubmed.ncbi.nlm.nih.gov/23618447
https://pubmed.ncbi.nlm.nih.gov/23618447
Autor:
H. N. Bramson, Kenneth Batchelor, J. E. Long, Roger N. Hiner, Frank Lee, Marcia L. Moss, R. A. Jun. Mook, J. D. Stuart, J. Van Arnold, Stephen V. Frye, Stephanie L. Schweiker, Mary K. Grizzle, Curt D. Haffner, Michael K. James, Timothy K. Tippin, G. Tian, Patrick R. Maloney, S V Schuster, D. M. Bickett, Rayomand J. Unwalla, G. F. Jun. Dorsey
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c365d9b240d68257c530bd93326438d1
https://doi.org/10.1002/chin.199426234
https://doi.org/10.1002/chin.199426234
Autor:
J. Van Arnold, Kenneth Batchelor, J. D. Stuart, Stephanie L. Schweiker, D. M. Bickett, Robert Carl Andrews, Wheeler Thomas Neil, Stephen V. Frye, Frank Lee, R. A. Jun. Mook, R. N. Hiner, Patrick R. Maloney, Curt D. Haffner, John A. Ray, G. F. Jun. Dorsey, H. N. Bramson, G. Tian, Rayomand J. Unwalla, Marcia L. Moss, Cynthia Markert Cribbs, S. Croom
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43716e15564e96bfa75547adc6350a3e
https://doi.org/10.1002/chin.199451227
https://doi.org/10.1002/chin.199451227
Autor:
David M. Bickett, Pierette Banker, Daphne C. Clancy, Joyce A. Boucheron, Stephen A. Thomson, James E. Weiel, and Andrew J. Peat, Dulce Garrido, Steven M. Sparks, Francis X. Tavares, Lauren R. Sheckler, Joel P. Cooper, Scott Howard Dickerson, Liping Wang, Tony Y. Wang, Robert T. Nolte, H.L. Carter
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(4)
Key binding interactions of the anthranilimide based glycogen phosphorylase a (GPa) inhibitor 2 from X-ray crystallography studies are described. This series of compounds bind to the AMP site of GP. Using the binding information the core and the phen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::315bf00dccdab187675054ab81ac0fef
https://pubmed.ncbi.nlm.nih.gov/19138846
https://pubmed.ncbi.nlm.nih.gov/19138846
Autor:
J G, Conway, R C, Andrews, B, Beaudet, D M, Bickett, V, Boncek, T A, Brodie, R L, Clark, R C, Crumrine, M A, Leenitzer, D L, McDougald, B, Han, K, Hedeen, P, Lin, M, Milla, M, Moss, H, Pink, M H, Rabinowitz, T, Tippin, P W, Scates, J, Selph, S A, Stimpson, J, Warner, J D, Becherer
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 298(3)
Tumor necrosis factor-alpha (TNF)-converting enzyme (TACE) cleaves the precursor form of TNF, allowing the mature form to be secreted into the extracellular space. GW3333, a dual inhibitor of TACE and matrix metalloproteinases (MMPs), was compared wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::50836d54042647696574068bd0ddb75e
https://pubmed.ncbi.nlm.nih.gov/11504783
https://pubmed.ncbi.nlm.nih.gov/11504783
Publikováno v:
Methods in enzymology. 248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e8c7e5459833b7857f024774fec51ca
https://pubmed.ncbi.nlm.nih.gov/7674932
https://pubmed.ncbi.nlm.nih.gov/7674932
Publikováno v:
The Journal of biological chemistry. 269(52)
The peptide substrate specificities of two matrix metalloproteinases (MMPs), interstitial collagenase (MMP-1), and 92-kDa gelatinase (MMP-9), have been examined. Starting with the parent substrate, Dnp-Pro-Leu-Gly approximately Leu-Trp-Ala-D-Arg-NH2,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::957b91aefadb80575ef85f39dd4981b7
https://pubmed.ncbi.nlm.nih.gov/7806505
https://pubmed.ncbi.nlm.nih.gov/7806505