Zobrazeno 1 - 10
of 16
pro vyhledávání: '"M. Betina Pampena"'
Autor:
Maria Pino, Amélie Pagliuzza, M. Betina Pampena, Claire Deleage, Elise G. Viox, Kevin Nguyen, Inbo Shim, Adam Zhang, Justin L. Harper, Sadia Samer, Colin T. King, Barbara Cervasi, Kiran P. Gill, Stephanie Ehnert, Sherrie M. Jean, Michael L. Freeman, Jeffrey D. Lifson, Deanna Kulpa, Michael R. Betts, Nicolas Chomont, Michael M. Lederman, Mirko Paiardini
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Although antiretroviral therapy (ART) is able to successfully suppress plasma viremia in most people living with HIV, ART withdrawal typically results in viral replication and rebound. Authors investigate the effect, in terms of delay in viral replic
Externí odkaz:
https://doaj.org/article/02897c95d48247e0867184e05e8cc7b9
Autor:
Lili Wang, Claude C. Warzecha, Alexander Kistner, Jessica A. Chichester, Peter Bell, Elizabeth L. Buza, Zhenning He, M. Betina Pampena, Julien Couthouis, Sunjay Sethi, Kathleen McKeever, Michael R. Betts, Emil Kakkis, James M. Wilson, Samuel Wadsworth, Barbara A. Sullivan
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 24, Iss , Pp 292-305 (2022)
Ornithine transcarbamylase deficiency is a rare X-linked genetic urea cycle disorder leading to episodes of acute hyperammonemia, adverse cognitive and neurological effects, hospitalizations, and in some cases death. DTX301, a non-replicating, recomb
Externí odkaz:
https://doaj.org/article/0bb545c351f24bafb56d6307da45c4b4
Autor:
Christopher V. Cosgriff, MD, MPH, Todd A. Miano, PhD, PharmD, Divij Mathew, PhD, Alexander C. Huang, MD, PhD, Heather M. Giannini, MD, MS, Leticia Kuri-Cervantes, PhD, M. Betina Pampena, PhD, Caroline A. G. Ittner, PhD, Ariel R. Weisman, MS, Roseline S. Agyekum, BS, Thomas G. Dunn, BS, Oluwatosin Oniyide, BS, Alexandra P. Turner, BS, Kurt D’Andrea, BS, Sharon Adamski, BS, Allison R. Greenplate, PhD, Brian J. Anderson, MD, MSCE, Michael O. Harhay, PhD, Tiffanie K. Jones, MD, MPH, MSCE, John P. Reilly, MD, MSCE, Nilam S. Mangalmurti, MD, Michael G. S. Shashaty, MD, MSCE, Michael R. Betts, PhD, E. John Wherry, PhD, Nuala J. Meyer, MD, MS
Publikováno v:
Critical Care Explorations, Vol 4, Iss 12, p e0800 (2022)
OBJECTIVES:. COVID-19 is a heterogenous disease. Biomarker-based approaches may identify patients at risk for severe disease, who may be more likely to benefit from specific therapies. Our objective was to identify and validate a plasma protein signa
Externí odkaz:
https://doaj.org/article/987a6075e22c4b8b8c873ee3a0bd699e
Autor:
Cécile, Alanio, Anurag, Verma, Divij, Mathew, Sigrid, Gouma, Guanxiang, Liang, Thomas, Dunn, Derek A, Oldridge, JoEllen, Weaver, Leticia, Kuri-Cervantes, M Betina, Pampena, Michael R, Betts, Ronald G, Collman, Frederic D, Bushman, Nuala J, Meyer, Scott E, Hensley, Daniel, Rader, E John, Wherry, Ashley N, Vanderbeck
Publikováno v:
The Journal of Infectious Diseases. 226:463-473
Some risk factors for severe coronavirus disease 2019 (COVID-19) have been identified, including age, race, and obesity. However, 20%–50% of severe cases occur in the absence of these factors. Cytomegalovirus (CMV) is a herpesvirus that infects abo
Autor:
Devivasha Bordoloi, Abhijeet J. Kulkarni, Opeyemi S. Adeniji, M Betina Pampena, Pratik S. Bhojnagarwala, Shushu Zhao, Elizabeth M. Parzych, Rugang Zhang, Michael R. Betts, Mohamed Abdel-Mohsen, David B. Weiner
Publikováno v:
Cancer Research. 83:4263-4263
High grade serous ovarian cancer (OC) and ovarian carcinosarcoma, referred as “Cold” tumors have restricted treatment choices and being associated with high mortality. Current immune checkpoint inhibitors (CPIs) have had modest impact for OC trea
Autor:
Ariel R. Weisman, Caroline A. G. Ittner, Ann H. Rux, Nuala J. Meyer, S. Murphy, Wen-Chao Song, John D. Lambris, Nilam S. Mangalmurti, Michael R. Betts, Leticia Kuri-Cervantes, Douglas B. Cines, John P. Reilly, E. John Wherry, M. Betina Pampena, L. K. Metthew Lam
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
COVID-19, the disease caused by the SARS-CoV-2 virus, can progress to multi-organ failure characterized by respiratory insufficiency, arrhythmias, thromboembolic complications and shock. The mortality of patients hospitalized with COVID-19 is unaccep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac15f5c715ea0060da803fb9e3599170
https://europepmc.org/articles/PMC8384475/
https://europepmc.org/articles/PMC8384475/
Autor:
Eileen C. Goodwin, Peyton Conrey, Divij Mathew, E. John Wherry, Heather M. Giannini, Cécile Alanio, Kevin O McNerney, Leticia Kuri-Cervantes, Marcus J. Bolton, Josephine R. Giles, Sigrid Gouma, Samir Sayed, Laura A. Vella, Jessica H. Lee, Julie Chase, Oliva Kuthuru, Claudia P. Arevalo, Scott E. Hensley, Zeyu Chen, Chakkapong Burudpakdee, Sarah E. Henrickson, Derek A. Oldridge, Amy E. Baxter, David T. Teachey, Kurt D'Andrea, Andre Ramos, Caroline Diorio, Hamid Bassiri, Nuala J. Meyer, Elizabeth M. Anderson, M. Betina Pampena, Edward M. Behrens, Yinghui Jane Huang, Sokratis A. Apostolidis, Madison E. Weirick, Jennifer E. Wu, Alexander C. Huang, Cristina Jasen, Michael R. Betts
Publikováno v:
Science Immunology
medRxiv
medRxiv
MIS-C is defined by lymphocyte activation, including elevated plasmablast frequencies and marked activation of CX3CR1+ CD8+ T cells.
Pediatric COVID-19 following SARS-CoV-2 infection is associated with fewer hospitalizations and often milder dis
Pediatric COVID-19 following SARS-CoV-2 infection is associated with fewer hospitalizations and often milder dis
Autor:
Laura A. Vella, Madison E. Weirick, Ajinkya Pattekar, Luanne Bershaw, Ariel R. Weisman, Claudia P. Arevalo, Michael R. Betts, Nicholas Han, Leticia Kuri-Cervantes, Marcus J. Bolton, Divij Mathew, Sigrid Gouma, Eline T. Luning Prak, Scott E. Hensley, Wenzhao Meng, Caroline A. G. Ittner, Justin Kim, Eileen C. Goodwin, Allison R. Greenplate, Jeanette Dougherty, E. John Wherry, Amy E. Baxter, Tiffanie K. Jones, Oliva Kuthuru, Aaron M. Rosenfeld, Nuala J. Meyer, R.S. Agyekum, Nilam S. Mangalmurti, M. Betina Pampena, Elizabeth M. Anderson, Sokratis A. Apostolidis
Publikováno v:
Science Immunology
Although critical illness has been associated with SARS-CoV-2-induced hyperinflammation, the immune correlates of severe COVID-19 remain unclear. Here, we comprehensively analyzed peripheral blood immune perturbations in 42 SARS-CoV-2 infected and re
Autor:
Ariel R. Weisman, Ajinkya Pattekar, Fang Chen, Caroline A. G. Ittner, Cécile Alanio, Sasikanth Manne, Zeyu Chen, E. John Wherry, Holly Ramage, M. Betina Pampena, Scott E. Hensley, Kito Nzingha, Justin Kim, Amy E. Baxter, Jeanette Dougherty, Divij Mathew, Michael R. Betts, Allison R. Greenplate, Claudia P. Arevalo, Yinghui Jane Huang, Leticia Kuri-Cervantes, Josephine R. Giles, Derek A. Oldridge, Nuala J. Meyer, Jennifer E. Wu, Marcus J. Bolton, Laura A. Vella, John P. Reilly, Alexander C. Huang, Elizabeth M. Anderson, Eileen C. Goodwin, Madison E. Weirick, Simon F. Lacey, Sokratis A. Apostolidis, Sara Cherry, Kurt D'Andrea, Nicholas Han, Sigrid Gouma, Oliva Kuthuru
Publikováno v:
Science
Science (New York, N.y.)
Science (New York, N.y.)
Immune profiling of COVID-19 patients Coronavirus disease 2019 (COVID-19) has affected millions of people globally, yet how the human immune system responds to and influences COVID-19 severity remains unclear. Mathew et al. present a comprehensive at
Autor:
Leticia Kuri-Cervantes, M. Betina Pampena, Wenzhao Meng, Aaron M. Rosenfeld, Caroline A.G. Ittner, Ariel R. Weisman, Roseline Agyekum, Divij Mathew, Amy E. Baxter, Laura Vella, Oliva Kuthuru, Sokratis Apostolidis, Luanne Bershaw, Jeannete Dougherty, Allison R. Greenplate, Ajinkya Pattekar, Justin Kim, Nicholas Han, Sigrid Gouma, Madison E. Weirick, Claudia P. Arevalo, Marcus J. Bolton, Eileen C. Goodwin, Elizabeth M. Anderson, Scott E. Hensley, Tiffanie K. Jones, Nilam S. Mangalmurti, Eline T. Luning Prak, E. John Wherry, Nuala J. Meyer, Michael R. Betts
Publikováno v:
bioRxiv
Although critical illness has been associated with SARS-CoV-2-induced hyperinflammation, the immune correlates of severe COVID-19 remain unclear. Here, we comprehensively analyzed peripheral blood immune perturbations in 42 SARS-CoV-2 infected and re