Zobrazeno 1 - 10
of 1 257
pro vyhledávání: '"M. Beekman"'
Autor:
F. A. Bogaards, T. Gehrmann, M. Beekman, N. Lakenberg, H. E. D. Suchiman, C. P. G. M. de Groot, M. J. T. Reinders, P. E. Slagboom
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Molecular effects of lifestyle interventions are typically studied in a single tissue. Here, we perform a secondary analysis on the sex-specific effects of the Growing Old TOgether trial (GOTO, trial registration number GOT NL3301 ( https://
Externí odkaz:
https://doaj.org/article/3fe10dc5ea2c483585c22b8ce02587f2
Autor:
Daniele Bizzarri, Marcel J.T. Reinders, Lieke Kuiper, Marian Beekman, Joris Deelen, Joyce B.J. van Meurs, Jenny van Dongen, René Pool, Dorret I. Boomsma, Mohsen Ghanbari, Lude Franke, Pieternella E. Slagboom, Erik B. van den Akker, J.M. Geleijnse, E. Boersma, W.E. van Spil, M.M.J. van Greevenbroek, C.D.A. Stehouwer, C.J.H. van der Kallen, I.C.W. Arts, F. Rutters, J.W.J. Beulens, M. Muilwijk, P.J.M. Elders, L.M. 't Hart, M. Ghanbari, M.A. Ikram, M.G. Netea, M. Kloppenburg, Y.F.M. Ramos, N. Bomer, I. Meulenbelt, K. Stronks, M.B. Snijder, A.H. Zwinderman, B.T. Heijmans, L.H. Lumey, C. Wijmenga, J. Fu, A. Zhernakova, J. Deelen, S.P. Mooijaart, M. Beekman, P.E. Slagboom, G.L.J. Onderwater, A.M.J.M. van den Maagdenberg, G.M. Terwindt, C. Thesing, M. Bot, B.W.J.H. Penninx, S. Trompet, J.W. Jukema, N. Sattar, I.C.C. van der Horst, P. van der Harst, C. So-Osman, J.A. van Hilten, R.G.H.H. Nelissen, I.E. Höfer, F.W. Asselbergs, P. Scheltens, C.E. Teunissen, W.M. van der Flier, J. van Dongen, R. Pool, A.H.M. Willemsen, D.I. Boomsma, H.E.D. Suchiman, J.J.H. Barkey Wolf, D. Cats, H. Mei, M. Slofstra, M. Swertz, M.J.T. Reinders, E.B. van den Akker
Publikováno v:
EBioMedicine, Vol 107, Iss , Pp 105279- (2024)
Summary: Background: 1H-NMR metabolomics and DNA methylation in blood are widely known biomarkers predicting age-related physiological decline and mortality yet exert mutually independent mortality and frailty signals. Methods: Leveraging multi-omics
Externí odkaz:
https://doaj.org/article/dd2f1125885a4ef2be328f0b36ea785b
Autor:
M. S. Moreira, G. G. Guerreschi, W. Vlothuizen, J. F. Marques, J. van Straten, S. P. Premaratne, X. Zou, H. Ali, N. Muthusubramanian, C. Zachariadis, J. van Someren, M. Beekman, N. Haider, A. Bruno, C. G. Almudever, A. Y. Matsuura, L. DiCarlo
Publikováno v:
npj Quantum Information, Vol 9, Iss 1, Pp 1-7 (2023)
Abstract Artificial neural networks are becoming an integral part of digital solutions to complex problems. However, employing neural networks on quantum processors faces challenges related to the implementation of non-linear functions using quantum
Externí odkaz:
https://doaj.org/article/c6b733651ed3421f812c27499c272c26
Autor:
R. Sagastizabal, S. P. Premaratne, B. A. Klaver, M. A. Rol, V. Negîrneac, M. S. Moreira, X. Zou, S. Johri, N. Muthusubramanian, M. Beekman, C. Zachariadis, V. P. Ostroukh, N. Haider, A. Bruno, A. Y. Matsuura, L. DiCarlo
Publikováno v:
npj Quantum Information, Vol 7, Iss 1, Pp 1-7 (2021)
Abstract The preparation of thermal equilibrium states is important for the simulation of condensed matter and cosmology systems using a quantum computer. We present a method to prepare such mixed states with unitary operators and demonstrate this te
Externí odkaz:
https://doaj.org/article/a4e1a9bbc9694af492d5bbcf1513f7a0
Publikováno v:
EBioMedicine, Vol 75, Iss , Pp 103764- (2022)
Summary: Background: Missing or incomplete phenotypic information can severely deteriorate the statistical power in epidemiological studies. High-throughput quantification of small-molecules in bio-samples, i.e. ‘metabolomics’, is steadily gainin
Externí odkaz:
https://doaj.org/article/4fa8cc75b5e04b80b85e399eea26cf6e
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Sacha Spelier, Eveline P.M. van Doorn, Cornelis K. van der Ent, Jeffrey M. Beekman, Martijn A.J. Koppens
Publikováno v:
Trends in Molecular Medicine. 29:297-314
Autor:
Sacha Spelier, Eyleen de Poel, Georgia N. Ithakisiou, Sylvia W.F. Suen, Marne C. Hagemeijer, Danya Muilwijk, Annelotte M. Vonk, Jesse E. Brunsveld, Evelien Kruisselbrink, Cornelis K. van der Ent, Jeffrey M. Beekman
Publikováno v:
ERJ Open Research. 9:00495-2022
BackgroundCystic fibrosis (CF) is a rare hereditary disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Recent therapies enable effective restoration of CFTR function of the most common F508delCFTRmutat
Autor:
Lindeboom, Henriette H. M. Dreyer, Eleonora Sofie van Tuyll van Serooskerken, Lisa W. Rodenburg, Arnold J. N. Bittermann, Hubertus G. M. Arets, Ellen M. B. P. Reuling, Johannes W. Verweij, Eric G. Haarman, David C. van der Zee, Stefaan H. A. J. Tytgat, Cornelis K. van der Ent, Jeffrey M. Beekman, Gimano D. Amatngalim, Maud Y. A.
Publikováno v:
Children; Volume 10; Issue 6; Pages: 1020
Esophageal atresia (EA) is a rare birth defect in which respiratory tract disorders are a major cause of morbidity. It remains unclear whether respiratory tract disorders are in part caused by alterations in airway epithelial cell functions such as t
Autor:
M. Beekman
Publikováno v:
Insectes Sociaux.