Mining for natural product antileishmanials in a fungal extract library

Autor: J. Steele, B. Kebede, C. Regnault, S.K. Wrigley, Michael P. Barrett, Lynn Evans, Paul W. Denny, Alison Mbekeani, J. Elliot, R.S. Jones, M. Bassas Llorens

Publikováno v: International journal for parasitology : drugs and drug resistance, 2019, Vol.11, pp.118-128 [Peer Reviewed Journal]
International Journal for Parasitology: Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance, Vol 11, Iss, Pp 118-128 (2019)

Leishmaniasis is a Neglected Tropical Disease caused by the insect-vector borne protozoan parasite, Leishmania species. Infection affects millions of the World's poorest, however vaccines are absent and drug therapy limited. Recently, public-private

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f72ead6f3f9f17e76bb40edd4b2fcff
http://dro.dur.ac.uk/28513/

The antifungal Aureobasidin A and an analogue are active against the protozoan parasite Toxoplasma gondii but do not inhibit sphingolipid biosynthesis – Corrigendum

Autor: A Q I, Alqaisi, A J, Mbekeani, M Bassas, Llorens, A P, Elhammer, P W, Denny

Publikováno v: Parasitology

SUMMARY Toxoplasma gondii is an obligate intracellular protozoan parasite of the phylum Apicomplexa, and toxoplasmosis is an important disease of both humans and economically important animals. With a limited array of drugs available there is a need

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29879d052e84a18b609d7ec93008ade7
http://europepmc.org/articles/PMC5964473