Zobrazeno 1 - 10
of 166
pro vyhledávání: '"M. B. Widmer"'
Publikováno v:
Tissue Antigens. 3:309-315
The major histocompatibility complex (MHC) in the mouse is the strongest barrier to allograft survival. One measure of MHC disparity is the mixed leuk,ocyte culture (MLC) test in which lymphocytes from a potential recipient strain, respond to mitomyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c089bafd092363875b703482afd1f3d
https://doi.org/10.1111/j.1399-0039.1973.tb01008.x
https://doi.org/10.1111/j.1399-0039.1973.tb01008.x
Publikováno v:
The Journal of Immunology. 156:1339-1348
This study was designed to compare the interactions of IL-2 and IL-15 with the IL-2R beta and IL-2R gamma c subunits, as differences in receptor interactions between IL-2 and IL-15 might contribute to the functional differences between these two cyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18aacac3b78a7909c03259696834aefc
https://doi.org/10.4049/jimmunol.156.4.1339
https://doi.org/10.4049/jimmunol.156.4.1339
Autor:
S Nagoya, P D Greenberg, C Yee, K E Weisser, H Sugawara, M B Widmer, J Slack, S K Dower, S D Lupton, R W Overell
Publikováno v:
The Journal of Immunology. 153:1527-1535
Although the proliferation of CD8+ CTL typically requires cytokine support provided by helper T cells, a subset of naturally occurring CD8+ CTL are capable of proliferating independently of T cell help. Such helper-independent CTL have previously bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac547dc6fa8ef81dfc72b5f3b7e1f543
https://doi.org/10.4049/jimmunol.153.4.1527
https://doi.org/10.4049/jimmunol.153.4.1527
Publikováno v:
The Journal of Immunology. 151:6602-6607
A recombinant human TNF receptor Fc fusion protein (rhuTNFR:Fc) was assessed for antiarthritic activity using murine type II collagen-induced arthritis in mice. DBA/1 mice were immunized with bovine type II collagen and treated with rhuTNFR:Fc either
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f68a9e23c7ae5e3bebb78e903dcb9af
https://doi.org/10.4049/jimmunol.151.11.6602
https://doi.org/10.4049/jimmunol.151.11.6602
Autor:
K M Mohler, D S Torrance, C A Smith, R G Goodwin, K E Stremler, V P Fung, H Madani, M B Widmer
Publikováno v:
The Journal of Immunology. 151:1548-1561
Two forms (monomeric or dimeric) of the extracellular, ligand-binding portion of the human p80 cell-surface receptor for TNF were used to antagonize TNF activity in vitro and in vivo. The dimeric sTNFR:Fc molecule was a more potent inhibitor of TNF t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02e0bf0837af8eade765e0916e2011d4
https://doi.org/10.4049/jimmunol.151.3.1548
https://doi.org/10.4049/jimmunol.151.3.1548
Publikováno v:
The Journal of Immunology. 150:2717-2723
This study examines the effects of soluble IL-4R (sIL-4R) administration on IgE production in vivo by using an anti-IgD injection model. Anti-IgD-treated mice were given various doses of sIL-4R or anti-IL-4 mAb over a 3-day period and serum IgE level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16b6cbefb2073224186bac16c88c53b7
https://doi.org/10.4049/jimmunol.150.7.2717
https://doi.org/10.4049/jimmunol.150.7.2717
Publikováno v:
The Journal of Immunology. 147:535-540
Although numerous in vitro studies have demonstrated that cytokines are involved in the generation of alloreactive effector cells, the role of these regulatory substances in vivo is less well defined. We have recently cloned and expressed cDNAs encod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bc3fbdf25dd7b97a4b4e9391d610f60
https://doi.org/10.4049/jimmunol.147.2.535
https://doi.org/10.4049/jimmunol.147.2.535
Publikováno v:
The Journal of Experimental Medicine
The effects of purified recombinant interleukin 7 (IL-7) on the generation of cytolytic T lymphocytes (CTL) in mixed lymphocyte culture (MLC) and on the induction of lymphokine-activated killer (LAK) cells in autologous cultures of human peripheral b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9700b808a2bb244c201d807434de22f2
https://doi.org/10.1084/jem.172.2.577
https://doi.org/10.1084/jem.172.2.577
Publikováno v:
The Journal of Immunology. 144:3015-3020
The regulation of murine T cell proliferation by IL-7 was investigated. Highly purified resting splenic T cells were induced to proliferate in a short term assay by IL-7 in the presence of the comitogen, Con A. The proliferation of these resting T ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c6c188abd4d803a2cc1eed41fcfc780
https://doi.org/10.4049/jimmunol.144.8.3015
https://doi.org/10.4049/jimmunol.144.8.3015
Autor:
B Mosley, Stewart D. Lyman, M B Widmer, Linda S. Park, S D Gimpel, T Vanden Bos, Carl J. March, Kenneth H. Grabstein, W S Din, R L Idzerda
Publikováno v:
The Journal of Experimental Medicine
IL-4, a pleiotropic cytokine produced by T lymphocytes, plays an important role in immune responsiveness by regulating proliferation and differentiation of a variety of lymphoid and myeloid cells via binding to high affinity receptors. In this report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2338596286fe2466874b2cddca9590b
https://doi.org/10.1084/jem.171.3.861
https://doi.org/10.1084/jem.171.3.861