Zobrazeno 1 - 10
of 13
pro vyhledávání: '"M. B. Perlman"'
Publikováno v:
Journal of Applied Physiology. 58:1421-1427
We examined the effect of fibrinolysis depression on thrombin-induced pulmonary microembolism in awake sheep prepared with chronic lung lymph fistulas. Fibrinolysis was depressed by an intravenous infusion (100 mg) of tranexamic acid [trans-4-(Aminom
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 252:H605-H614
We compared pulmonary vascular responses with thrombin-induced pulmonary microembolism in awake sheep pretreated with ibuprofen or meclofenamate. Control sheep with lung lymph fistulas (n = 6) were challenged with 80 U/kg of alpha-thrombin, the nativ
Publikováno v:
Circulation Research. 59:405-415
We investigated the effects of superoxide dismutase (SOD) and SOD linked to Ficoll (mol. wt = 400,000) on the changes in pulmonary transvascular fluid and protein exchange following pulmonary microembolism induced with alpha-thrombin. Studies were ma
Autor:
Joe G.N. Garcia, M. B. Perlman, William Jubiz, Thomas J. Ferro, Arnold Johnson, Asrar B. Malik
Publikováno v:
American Review of Respiratory Disease. 137:630-635
We performed bronchoalveolar lavage (BAL) 0.5 to 24 h after thrombin-induced pulmonary microembolization in spontaneously breathing sheep to examine the inflammatory events that occur after pulmonary intravascular coagulation. Neutrophil alveolitis w
Publikováno v:
Journal of Applied Physiology. 60:546-553
We determined the effects of infusion of prostacyclin (PGI2) and 6-alpha-carba-PGI2 (6-cPGI2), a stable PGI2 analogue, on pulmonary transvascular fluid and protein fluxes after intravascular coagulation induced by thrombin. Studies were made in contr
Publikováno v:
Circulation Research. 64:62-73
We examined the mechanism of the neutrophil (PMN)-dependent increase in pulmonary vascular permeability to protein after thrombin-induced pulmonary microembolism. Humoral factors that activate PMNs after thrombin-induced pulmonary microembolism were
Publikováno v:
Federation proceedings. 44(1 Pt 1)
Arachidonic acid metabolites produced by cyclooxygenase and lipoxygenase pathways affect pulmonary transvascular fluid and protein fluxes after pulmonary microvascular injury. Some of these products may contribute to the increase microvascular endoth
Publikováno v:
The American review of respiratory disease. 136(4)
Although the etiology of rheumatoid interstitial lung disease (RILD) remains unknown, bronchoalveolar lavage (BAL) has been useful in studying potentially pathogenic mechanisms in this disorder. Previous investigations in patients with rheumatoid art
Publikováno v:
Pediatric Research. 19:413A-413A
1815 PULMONARY VASCULAR PERMEABILITY TO PROTEINS INCREASES AFTER THROMBIN-INDUCED INTRAVASCULAR COAGULATION
Publikováno v:
Pediatric Research. 18:328A-328A
Controversy exists over providing intensive care to VLBW infants. We examined the effects of current intensive care on survival and neurologic outcome on 121 infants of birth weight (BW) 500-1000 gm born in 1981-82, and identified factors associated