Zobrazeno 1 - 10
of 96
pro vyhledávání: '"M. B. Navrotskii"'
Autor:
A. S. Mkrtchyan, Konstantin V. Balakin, D. S. Sheikin, L. L. Brunilina, Ivan A. Novakov, M. B. Navrotskii
Publikováno v:
Russian Chemical Bulletin. 69:1625-1671
The review addresses the complete anthology of the development and evolution of dexoxadrol derivatives comprising a class of highly efficient NMDA receptor antagonists. Main approaches to the synthesis of dexoxadrol and enantiomeric 1-(2-piperidyl)et
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49d00dc08f4108ed4515f759b9fcbc1e
https://doi.org/10.1007/s11172-020-2946-9
https://doi.org/10.1007/s11172-020-2946-9
Autor:
Dmitry S. Sheikin, A. Yu. Maryshev, A. S. Babushkin, Dominique Schols, V. V. Chapurkin, Ivan A. Novakov, M. B. Navrotskii, Evsey A. Ruchko
Publikováno v:
Russian Journal of General Chemistry. 90:352-356
The Tscherniac–Einhorn reaction of 6-methyl and 6-(trifluoromethyl) derivatives of 2-thiouracil with N-(bromomethyl)phthalimide in under basic catalysis leads to the formation of S-amidomethylation products. When using 6-amino-2-thiouracil, decompo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34fc8faa527b35aafc0cca4c05f1ae52
https://doi.org/10.1134/s1070363220030056
https://doi.org/10.1134/s1070363220030056
Autor:
M. B. Navrotskii, R. V. Brunilin, A. A. Vernigora, S. N. Voloboev, G. M. Butov, A. S. Yablokov, Ivan A. Novakov
Publikováno v:
Russian Journal of General Chemistry. 89:399-404
A significant effect of the steric factor on the activity of 3,5-dimethyl-1H-pyrazolide as an acylating agent has been found using the example of acylation of camphane-type monoamines. The predominant contribution of the catalytic hydrogenation as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91e7e6f0533d0db60e18e0e2f7ffa558
https://doi.org/10.1134/s1070363219030058
https://doi.org/10.1134/s1070363219030058
Autor:
L. L. Brunilina, E. A. Ruchko, A. A. Vernigora, Vadim V. Kachala, Ivan A. Novakov, D. S. Sheikin, I. A. Kirillov, A. S. Yablokov, A. S. Mkrtchyan, M. B. Navrotskii
Publikováno v:
Russian Journal of Organic Chemistry. 53:1844-1850
The aminolysis of 6-[1-(2,6-difluorophenyl)cyclopropyl]-5-methyl-2-(nitroamino)pyrimidin-4(3H)-one with various amines in butan-1-ol and under solvent-free conditions is successful when the amino group in the reagent is sterically unshielded and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::798cc86f191f0139086518b9227bb69d
https://doi.org/10.1134/s1070428017120107
https://doi.org/10.1134/s1070428017120107
Autor:
A. A. Vernigora, Boris S. Orlinson, S. N. Voloboev, M. B. Navrotskii, Ivan A. Novakov, A. S. Yablokov
Publikováno v:
Russian Chemical Bulletin. 66:1597-1600
A reaction of methyl 2-(4-allyl-2-methoxyphenoxy)acetate with adamantan-2-amine and (adamantan-1-yl)methylamine in butanol leads, together with the target amides, to the formation of butyl ester of the corresponding acid, which is resistant to aminol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::102dc7892a69a281ca51d42d72c6f476
https://doi.org/10.1007/s11172-017-1929-y
https://doi.org/10.1007/s11172-017-1929-y
Autor:
A. A. Vernigora, A. S. Babushkin, M. B. Navrotskii, S. N. Voloboev, A. S. Mkrtchyan, Ivan A. Novakov, Boris S. Orlinson
Publikováno v:
Russian Journal of Organic Chemistry. 53:663-672
Aiming at purposeful designing new conformationally labile bromantane analogs we performed experimental and theoretical evaluation of the basicity of new and formerly prepared compounds of this series. The connection was established between the chemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f164a23c20a480bc096b9442dd67ed6
https://doi.org/10.1134/s1070428017050049
https://doi.org/10.1134/s1070428017050049
Autor:
D. S. Sheikin, A. S. Babushkin, M. D. Robinovich, M. B. Navrotskii, Boris S. Orlinson, Ivan A. Novakov, S. N. Voloboev
Publikováno v:
Pharmaceutical Chemistry Journal. 50:781-787
New structural analogs of bromantane with greater conformational lability than the prototype were synthesized. Their physiological activity profiles were assessed in vivo. It was found that the analogs could be prepared under much milder conditions t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9e79525d2b51ab3430c90d762970ece
https://doi.org/10.1007/s11094-017-1531-5
https://doi.org/10.1007/s11094-017-1531-5
Autor:
E. A. Ruchko, A. A. Vernigora, M. B. Navrotskii, A. S. Babushkin, Vadim V. Kachala, A. S. Yablokov, Ivan A. Novakov, A. S. Mkrtchyan
Publikováno v:
Russian Journal of General Chemistry. 87:224-230
Special features of the synthesis and chemical transformations of novel functional derivatives of 6-[1-(2,6-dihalophenyl)cyclopropyl]pyrimidin-4(3H)-one and ethyl esters of 3-[1-(2,6-dihalophenyl)cyclopropyl]-2-methyl-3-oxopropanoic acids prepared fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69c9ae3265c6d5723c4bd4b55d03ef9c
https://doi.org/10.1134/s1070363217020128
https://doi.org/10.1134/s1070363217020128
Autor:
Ivan A. Novakov, Boris S. Orlinson, A. S. Yablokov, L. L. Brunilina, M. B. Navrotskii, A. S. Babushkin, M. D. Robinovich
Publikováno v:
Russian Journal of General Chemistry. 87:219-223
The application of bis-(4-nitrophenyl)phosphorylazide–1,8-diazabicyclo[5.4.0]undec-7-ene system for direct transformation of polyfunctional derivatives of pyrimidin-4(3H)-one in the corresponding 4-azidopyrimidines has been suggested for the first
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e77f1492b9327e68ea6a4e088a2b0a9
https://doi.org/10.1134/s1070363217020116
https://doi.org/10.1134/s1070363217020116
Autor:
A. S. Babushkin, A. A. Vernigora, Boris S. Orlinson, M. B. Navrotskii, Ivan A. Novakov, S. N. Voloboev, I. A. Kirillov
Publikováno v:
Russian Journal of General Chemistry. 86:2599-2605
Using the Leuckart–Wallach reaction, novel conformationally flexible structural analogs of Bromantane drug have been synthesized from 3-haloadamantane-1-carbaldehydes. Basic hydrolysis of the prepared compounds has been studied as a model of one of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b27cece1a1b4b35ed608e8af2ecc7d2c
https://doi.org/10.1134/s1070363216120057
https://doi.org/10.1134/s1070363216120057