Zobrazeno 1 - 10
of 13
pro vyhledávání: '"M. B. Gravestock"'
Autor:
D. H. G. Crout, B. E. P. Swoboda, D. R. Rathbone, C. O. Miles, R. J. Heath, S. Davies, M. B. Gravestock
Publikováno v:
Biocatalysis. 9:1-30
Peptides, and oligosaccharides and glycosides, can be synthesised by making use of the ‘reverse hydrolytic activity’ of proteases and glycosidases respectively. In applying these enzymes to the practical synthesis of these classes of compound, se
Publikováno v:
ChemInform. 25
Publikováno v:
ChemInform. 27
Autor:
M. B. Gravestock, R. A. Bell
Publikováno v:
Canadian Journal of Chemistry. 47:2099-2102
The rate of reduction of representative methyl esters with sodium trimethoxyborohydride decreases in the order primary > secondary > tertiary. Sodium trimethoxyborohydride reduces with 100% selectivity the secondary ester group in the alicyclic diest
Autor:
M. B. Gravestock, R. A. Bell
Publikováno v:
Canadian Journal of Chemistry. 47:3661-3670
The configuration and stereochemistry of methyl 11α-bromo-12-oxopodocarpan-19-oate 1 have been determined by application of the nuclear Overhauser effect. The dehydrobromination of 1 with dimethylacetamide–calcium carbonate results in a predominan
Publikováno v:
Canadian Journal of Chemistry. 50:3749-3760
A synthesis of lamberlianic acid 2a starting from podocarpic acid is described. The central intermediate, diester-ketone 4b, is obtained by ozonolysis and hydrogenation, and the exocyclic methylene group in ring B generated via a Reformatsky reaction
Autor:
M. B. Gravestock, R. A. Bell
Publikováno v:
Canadian Journal of Chemistry. 48:1105-1113
Low temperature ozonolysis of methyl podocarpate in methanol – methylene chloride results in the formation in high yield of 8β-hydroperoxy-8α-hydroxy-(13 → 17)-pentanorlabd-9(11)-en-12,19-dioic acid 19-methyl ester 8 → 12-lactone 4. Ozonolysi
Autor:
R. A. Bell, M. B. Gravestock
Publikováno v:
The Journal of Organic Chemistry. 37:1065-1067
Publikováno v:
ChemInform. 20
Publikováno v:
Advances in pharmacology and chemotherapy. 18