Zobrazeno 1 - 10
of 19
pro vyhledávání: '"M. B. Fiddler"'
Autor:
Marisa Alicea, M. B. Fiddler
Publikováno v:
NACADA Journal. 16:14-20
A set of advising competencies was developed by a collective examination of actual practices among faculty and staff who provide advising services to adult learners. A storytelling methodology provided the data from which skills, knowledge, attitudes
Publikováno v:
Pediatric Research. 9:918-923
Extract: The use of erythrocyte entrapment as a strategy to deliver and protect exogenously administered enzymes for replacement therapy in selected genetic diseases has been evaluated in a mammalian model system. The uptake, tissue distribution, int
Publikováno v:
Biochemical and Biophysical Research Communications. 61:1464-1470
Summary A mammalian model system was developed to determine the in vivo fate of intravenously administered bovine β-glucuronidase in β-glucuronidase deficient mice. Sensitive and reliable discrimination of bovine liver β-glucuronidase activity fro
Publikováno v:
Physiological Reviews. 56:57-99
Autor:
M B Fiddler, Robert J. Desnick
Publikováno v:
Archives of Biochemistry and Biophysics. 179:397-408
The in vivo fates of β-glucuronidase partially purified from bovine hepatic, renal, and splenic tissues were compared. Following administration to β-glucuronidase-deficient mice, hepatic and renal enzymes were primarily recovered in murine liver ly
Publikováno v:
Biomedical Applications of Immobilized Enzymes and Proteins ISBN: 9781468426120
Exploratory trials of enzyme replacement therapy have been stimulated by advances in the elucidation and characterization of the specific enzymatic defects in many inborn errors of metabolism, particularly the lysosomal storage diseases. The rational
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57f050cbf445b16d2e723429e01b2edd
https://doi.org/10.1007/978-1-4684-2610-6_16
https://doi.org/10.1007/978-1-4684-2610-6_16
Immunological evaluation of repeated administration of erythrocyte-entrapped protein to C3H/HeJ mice
The immunogenicity of heterologous protein entrapped in autologous erythrocytes was evaluated in a mouse system. Multiple intravenous administrations of an erythrocyte-entrapped bovine beta-glucuronidase preparation resulted in little, if any, immuno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad50862e7a99f2f54e9aa6ba5f2aa9bb
https://europepmc.org/articles/PMC1183745/
https://europepmc.org/articles/PMC1183745/
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 208(3)
Decreased binding by the lectins concanavalin A and wheat-germ agglutinin was found for a number of acidic hydrolases from skin fibroblasts of three unrelated patients with mucolipidosis II. This decreased binding as compared with normal controls was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::604c3f186420a74e749061903a9a1929
https://europepmc.org/articles/PMC1161087/
https://europepmc.org/articles/PMC1161087/
Publikováno v:
Advances in experimental medicine and biology. 101