5-HTT independent effects of fluoxetine on neuroplasticity

Autor: Corinne Poilbout, Gunter Kenis, Marion J. F. Levy, F. Boulle, Laurence Lanfumey, Harry W.M. Steinbusch, Daniel L.A. van den Hove, M. B. Emerit

Publikováno v: Scientific Reports, 9:6311. Nature Publishing Group
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)

Selective serotonin reuptake inhibitors are among the most prescribed antidepressants. Fluoxetine is the lead molecule which exerts its therapeutic effects, at least in part, by promoting neuroplasticity through increased brain-derived neurotrophic f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72fe245b0084ea2caf347d3a0fcbbce4
https://doi.org/10.1038/s41598-019-42775-w

Is the effect of fluoxetine on plasticity related to serotonin transporter or tropomyosin-related receptor kinase B?

Autor: H.W.M. Steinbusch, F. Boulle, M. B. Emerit, Laurence Lanfumey, D.L.A. van den Hove, Gunter Kenis, Marion J. F. Levy

Publikováno v: European Neuropsychopharmacology. 29:S348

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0cba0750c6b73f4d0342b2090d3c55c6
https://doi.org/10.1016/j.euroneuro.2018.11.540

A New Mechanism of Receptor Targeting by Interaction between Two Classes of Ligand-Gated Ion Channels

Autor: Eric Boué-Grabot, M. B. Emerit, Julie Areias, J. Diaz, Jeanine Alterio, Justine Masson, Michèle Darmon, Camille Baranowski, A. Martinez

Publikováno v: Journal of Neuroscience
Journal of Neuroscience, 2016, pp.1256-1470. ⟨10.1523/JNEUROSCI.2390-15.2016⟩
Journal of Neuroscience, Society for Neuroscience, 2016, pp.1256-1470. ⟨10.1523/JNEUROSCI.2390-15.2016⟩
Journal of Neuroscience, Society for Neuroscience, 2016, pp.1256-1470. 〈10.1523/JNEUROSCI.2390-15.2016〉

The 5-HT3receptors are serotonin-gated ion channels that physically couple with purinergic P2X2 receptors to trigger a functional cross-inhibition leading to reciprocal channel occlusion. Although this functional receptor–receptor coupling seems to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db350ce4b84604f0b15a1e6ccbf39923
https://europepmc.org/articles/PMC6601994/

Pharmacological Evidence for the Involvement of Calciuml Calmodulin in Serotonin 5-HT3 Receptor-Mediated Cation Permeability in NG 108-15 Cells

Autor: Michel Hamon, M. B. Emerit, M. Riad

Publikováno v: Journal of Neurochemistry. 62:2224-2232

In NG 108-15 clonal cells, extracellular application of micromolar concentrations of serotonin [5-hydroxytryptamine (5-HT)] and substance P induces the opening of a cation permeability monitored by the influx of [14C]-guanidinium. The serotoninergic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba39cb0769247f91b61d71cd9dfd5586
https://doi.org/10.1046/j.1471-4159.1994.62062224.x

Immunolabelling of the 5-HT3B receptor subunit in the central and peripheral nervous systems in rodents

Autor: M. B. Emerit, Alban Latremoliere, Michèle Darmon, Michel Hamon, E. Doucet

Publikováno v: European Journal of Neuroscience. 26:355-366

The 5-HT 3 receptor is a member of the superfamily of neurotransmitter-gated ion channels involved in fast synaptic signalling and in modulation of neurotransmitter release. As for many other channel receptors, the electrophysiological properties and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1efdb571b8eae4ab37b5d5745ea193ee
https://doi.org/10.1111/j.1460-9568.2007.05659.x