Zobrazeno 1 - 10
of 14
pro vyhledávání: '"M. B. Calvo"'
Autor:
Manoli Igartua, Rosa Maria Hernandez, Alicia R. Gascón, José Luis Pedraz, M. B. Calvo, A. Esquisabel
Publikováno v:
Journal of Controlled Release. 56:63-73
PLGA microspheres containing bovine serum albumin (BSA) as a model antigen, were prepared by a double emulsion/solvent extraction method and their in vitro characterization was performed. The same microspheres were used in a series of in vivo studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e4985c366af196f9a760f3df2acbf30
https://doi.org/10.1016/s0168-3659(98)00077-7
https://doi.org/10.1016/s0168-3659(98)00077-7
Autor:
Alicia R. Gascón, Manoli Igartua, M. B. Calvo, A. Esquisabel, José Luis Pedraz, R.M. Hernández
Publikováno v:
International Journal of Pharmaceutics. 169:45-54
Bovine serum albumin (BSA, Mw 66 200 Da) has been encapsulated as a model protein drug within poly(d,l-lactide-co-glycolide) (PLGA 50:50) microspheres using a w/o/w double emulsion method. The microspheres prepared were smooth and spherical with a me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff04c8edbddc6adf972eb2352ea948be
https://doi.org/10.1016/s0378-5173(98)00101-x
https://doi.org/10.1016/s0378-5173(98)00101-x
Autor:
M. A. Monte, J.L. Pedraz, Alicia R. Gascón, R.M. Hernández, A. M. Maza, Alfonso Domínguez-Gil, M. B. Calvo, J. J. G. Marin
Publikováno v:
Scopus-Elsevier
The influence of partial hepatectomy on the activity of the hepatic microsomal enzymatic systems was determined in rats. Cytochrome P-450, cytochrome b5, four mixed functional oxidase (MFO) activities (microsomal aniline hydroxylase, p-nitroanisole O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d883c736ee8e06c7a9377d4c3a3f9806
https://doi.org/10.1007/bf03189780
https://doi.org/10.1007/bf03189780
Autor:
M. B. Calvo, J.L. Pedraz, Alfonso Domínguez-Gil, R.M. Hernández, U. Conte, Alicia R. Gascón, Carla Caramella
Publikováno v:
International Journal of Pharmaceutics. 139:45-52
The purpose of this study was to investigate the possibility to develop different levels of correlation between ‘in vitro’ dissolution parameters and ‘in vivo’ pharmacokinetic parameters for four salbutamol sulphate formulations: two commerci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4371d3a8157ee1c31b56f6f90f1c18c9
https://doi.org/10.1016/0378-5173(96)04571-1
https://doi.org/10.1016/0378-5173(96)04571-1
Publikováno v:
Journal of Pharmaceutical Sciences. 85:1133-1135
The influence of partial hepatectomy on the pharmacokinetics of theophylline was determined in rats. The pharmacokinetics of intravenous theophylline was studied in unhepatectomized rats (control group: CG) and in hepatectomized rats (HG) 12 h after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4ee562a39b90f58de6172c248cb0512
https://doi.org/10.1021/js9600989
https://doi.org/10.1021/js9600989
Influence of hepatic regeneration after partial hepatectomy on theophylline pharmacokinetics in rats
Autor:
A. M. Maza, J.L. Pedraz, R.M. Hernández, Alicia R. Gascón, María Ángeles Solinís, M. B. Calvo
Publikováno v:
European journal of drug metabolism and pharmacokinetics. 26(1-2)
The influence of hepatic regeneration after partial hepatectomy on theophylline pharmacokinetics has been studied on the rat. At different times after partial hepatectomy, theophylline was administered intravenously as a single dose of 6 mg/Kg. Drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::415c9b1842a0557454c16f2e4c7633fb
https://pubmed.ncbi.nlm.nih.gov/11554434
https://pubmed.ncbi.nlm.nih.gov/11554434
Publikováno v:
International journal of pharmaceutics. 208(1-2)
The aim of the present work was to evaluate the influence of aging that might condition the release of salbutamol sulfate from oral formulations (lipid matrices) using Gelucire® as lipid excipients. Gelucires are essentially characterized by their m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e739de48f02bc9be0647fed38c96612
https://pubmed.ncbi.nlm.nih.gov/11064207
https://pubmed.ncbi.nlm.nih.gov/11064207
Publikováno v:
Scopus-Elsevier
The aim of the present work was to study the release of a model protein, bovine serum albumin (BSA) encapsulated within biodegradable poly (D,L-lactide-co-glycolide) (PLGA) microspheres prepared by a modified solvent evaporation method using a double
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b296a4195e88ff825cb70072d4e46d1f
https://pubmed.ncbi.nlm.nih.gov/9725463
https://pubmed.ncbi.nlm.nih.gov/9725463
Publikováno v:
International journal of clinical pharmacology, therapy, and toxicology. 25(2)
The evolution of the plasma levels of ketamine and its two biotransformation products, norketamine (metabolite I) and dehydronorketamine (metabolite II) was studied after i.v. and epidural administration at doses of 2 and 5 mg/kg, respectively. The r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::91b48eda3b75dfb0ee8ae66fc36105ca
https://pubmed.ncbi.nlm.nih.gov/3557733
https://pubmed.ncbi.nlm.nih.gov/3557733
Publikováno v:
International journal of clinical pharmacology, therapy, and toxicology. 26(5)
The pharmaceutical preparations of paracetamol Duorol and Termalgin, both containing 500 mg of active compound, were studied to test their bioequivalence. The results obtained showed that absorption of the drug follows two sequential kinetic processe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5a976a40ae61449045fe0d2dcc366f54
https://pubmed.ncbi.nlm.nih.gov/3410598
https://pubmed.ncbi.nlm.nih.gov/3410598