Zobrazeno 1 - 10
of 5 316
pro vyhledávání: '"M. Anttila"'
Autor:
Denis Belitškin, Pauliina Munne, Shishir M. Pant, Johanna M. Anttila, Ilida Suleymanova, Kati Belitškina, Daniel Kirchhofer, James Janetka, Taivo Käsper, Sami Jalil, Jeroen Pouwels, Topi A. Tervonen, Juha Klefström
Publikováno v:
Molecular Oncology, Vol 18, Iss 3, Pp 547-561 (2024)
Hepsin, a type II transmembrane serine protease, is commonly overexpressed in prostate and breast cancer. The hepsin protein is stabilized by the Ras‐MAPK pathway, and, downstream, this protease regulates the degradation of extracellular matrix com
Externí odkaz:
https://doaj.org/article/3e25433eb30948a582897944f0e227ae
Publikováno v:
European Psychiatry, Vol 67, Pp S59-S59 (2024)
Introduction Violence in psychiatric inpatient settings is a global challenge. Several methods have been developed and tested to help staff prevent the occurrence of violence on the wards. One novel and effective method is eDASA+APP, originating from
Externí odkaz:
https://doaj.org/article/a37a920d77ac45d3a968b6c04c6ec1be
Autor:
Joyce V. Lee, Filomena Housley, Christina Yau, Rachel Nakagawa, Juliane Winkler, Johanna M. Anttila, Pauliina M. Munne, Mariel Savelius, Kathleen E. Houlahan, Daniel Van de Mark, Golzar Hemmati, Grace A. Hernandez, Yibing Zhang, Susan Samson, Carole Baas, Laura J. Esserman, Laura J. van ‘t Veer, Hope S. Rugo, Christina Curtis, Juha Klefström, Mehrdad Matloubian, Andrei Goga
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
The oncoprotein c-Myc is often overexpressed in triple negative breast cancer and has a role in tumor progression and resistance to therapy. Here the authors show that elevated MYC expression is correlated with low immune infiltration, diminished MHC
Externí odkaz:
https://doaj.org/article/5ba305a5a1f9497c9247af3f00c75bef
Autor:
Hussein Al‐Akhrass, Mika Pietilä, Johanna Lilja, Ella‐Maria Vesilahti, Johanna M. Anttila, Heidi M. Haikala, Pauliina M. Munne, Juha Klefström, Emilia Peuhu, Johanna Ivaska
Publikováno v:
Molecular Oncology, Vol 16, Iss 1, Pp 116-129 (2022)
In breast cancer, the currently approved anti‐receptor tyrosine‐protein kinase erbB‐2 (HER2) therapies do not fully meet the expected clinical goals due to therapy resistance. Identifying alternative HER2‐related therapeutic targets could off
Externí odkaz:
https://doaj.org/article/3226b21a139d4cb2aecf7f1e1b37a9ec
Autor:
Joyce V. Lee, Filomena Housley, Christina Yau, Rachel Nakagawa, Juliane Winkler, Johanna M. Anttila, Pauliina M. Munne, Mariel Savelius, Kathleen E. Houlahan, Daniel Van de Mark, Golzar Hemmati, Grace A. Hernandez, Yibing Zhang, Susan Samson, Carole Baas, Marleen Kok, Laura J. Esserman, Laura J. van ‘t Veer, Hope S. Rugo, Christina Curtis, Juha Klefström, Mehrdad Matloubian, Andrei Goga
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/c4c95fa626f54c138a7df8b82c363e2c
Autor:
H. Sallinen, S. Janhonen, P. Pölönen, H. Niskanen, O. H. Liu, A. Kivelä, J. M. Hartikainen, M. Anttila, M. Heinäniemi, S. Ylä-Herttuala, M. U. Kaikkonen
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background High grade serous ovarian carcinoma (HGSOC) is the most common subtype of epithelial ovarian cancers (EOC) with poor prognosis. In most cases EOC is widely disseminated at the time of diagnosis. Despite the optimal cytoreductive s
Externí odkaz:
https://doaj.org/article/23d2fd5ddaae4e6cb92fdda372490d3a
Autor:
Heidi M. Haikala, Johanna M. Anttila, Elsa Marques, Tiina Raatikainen, Mette Ilander, Henna Hakanen, Hanna Ala-Hongisto, Mariel Savelius, Diego Balboa, Bjoern Von Eyss, Vilja Eskelinen, Pauliina Munne, Anni I. Nieminen, Timo Otonkoski, Julia Schüler, Teemu D. Laajala, Tero Aittokallio, Harri Sihto, Johanna Mattson, Päivi Heikkilä, Marjut Leidenius, Heikki Joensuu, Satu Mustjoki, Panu Kovanen, Martin Eilers, Joel D. Leverson, Juha Klefström
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Elevated MYC levels can sensitize tumor cells to apoptosis. In this study, the authors demonstrate that AMPK activation and BCL-2/BCL-XL inhibition have a synergistic effect on apoptosis, and that together with anti PD-1 therapy they can suppress Myc
Externí odkaz:
https://doaj.org/article/d3f1f919795e44fe8702e5ba84a712b6
Publikováno v:
European Psychiatry, Vol 64, Pp S126-S127 (2021)
Introduction In the literature, service users and informal caregivers have been critical towards psychiatric inpatient care. However, little is known about their fears related to hospital care. Objectives We describe service users’ and informal c
Externí odkaz:
https://doaj.org/article/a5be9e31940248a699ac71fc5d376210
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