Zobrazeno 1 - 10
of 16
pro vyhledávání: '"M. Ann Kelly"'
Autor:
M Ann Kelly, Simon D Rees, M Zafar I Hydrie, A Samad Shera, Srikanth Bellary, J Paul O'Hare, Sudhesh Kumar, Shahrad Taheri, Abdul Basit, Anthony H Barnett, DIAGRAM Consortium, SAT2D Consortium
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e32670 (2012)
Disruption of endogenous circadian rhythms has been shown to increase the risk of developing type 2 diabetes, suggesting that circadian genes might play a role in determining disease susceptibility. We present the results of a pilot study investigati
Externí odkaz:
https://doaj.org/article/09e23ba8822b4ec5b81317635c37f156
Autor:
Simon D Rees, M Zafar I Hydrie, J Paul O'Hare, Sudhesh Kumar, A Samad Shera, Abdul Basit, Anthony H Barnett, M Ann Kelly
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24710 (2011)
BACKGROUND: The Meta-Analysis of Glucose and Insulin related traits Consortium (MAGIC) recently identified 16 loci robustly associated with fasting glucose, some of which were also associated with type 2 diabetes. The purpose of our study was to expl
Externí odkaz:
https://doaj.org/article/2cfc25109adc466bb0e2d780e408bad6
Autor:
M. Ann Kelly, Simon D. Rees, Vee P. Prasher, Steven C. Bain, Deepak Thalitaya, Anthony H. Barnett, Ashok Patel
Publikováno v:
Neuroscience Letters. 487:144-148
Background: Down syndrome (DS) is caused by either complete or partial triplication of chromosome 21, affecting approximately 1/1000 live births, and it is widely accepted that individuals with DS are more likely to develop dementia of Alzheimer's di
Autor:
M. A. Penny, Catherine H. Mijovic, D. A. Cavan, A. H. Barnett, David A. Francis, M. Ann Kelly, Kuang-Yen Chou, Yong Zhang, K. H. Jacobs
Publikováno v:
Human Immunology. 42:203-208
The association of MS with the HLA class II loci DR and DQ was investigated in subjects of Shanghai Chinese and British Caucasian origin. Our aim was to determine whether common alleles predispose to the disease in both races. In the Caucasian popula
Autor:
Nasser M. Al-Daghri, Nancy F. da Silva, Majed S. Alokail, Francesco P. Cappuccio, Shaun Sabico, Anthony H. Barnett, Michelle A. Miller, Sudhesh Kumar, M. Ann Kelly, Srikanth Bellary, Omar S. Al-Attas, Alison L. Harte, J. P. O'Hare, Philip G. McTernan, Gyanendra Tripathi
Publikováno v:
Experimental Diabetes Research, Vol 2012 (2012)
Experimental Diabetes Research
Experimental Diabetes Research
South Asians have a higher risk of type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD) than white Caucasians, for a given BMI. Premature biological ageing, assessed by reduction in telomere length (TL), may be mediated by factors resulti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55dff8b32057e8daafc2cc9aa4220392
http://wrap.warwick.ac.uk/44373/1/WRAP_Harte_895185.pdf
http://wrap.warwick.ac.uk/44373/1/WRAP_Harte_895185.pdf
Autor:
Asif Rasheed, Prasad Katulanda, Maria Samuel, Junbin Liang, Kee Seng Chia, E. Shyong Tai, Xinzhong Li, Chiea Chuen Khor, Mark I. McCarthy, Åsa K. Hedman, Zafar I. Hydrie, Muhammed Islam, Robin Young, Mingyu Yang, John Danesh, James Scott, Elin Grundberg, Panos Deloukas, Inga Prokopenko, Alexandra C. Nica, Simon D. Rees, Paul Zimmet, Mark Seielstad, Manickam Chidambaram, A. Samad Shera, David R. Matthews, Xueling Sim, Norihiro Kato, Philippe Froguel, Venkatesan Radha, Timothy M. Frayling, Nabi Shah, Weihua Zhang, Jeremy B M Jowett, Danish Saleheen, MuTHER, Joban Sehmi, Janani Pinidiyapathirage, Mark J. Caulfield, Tin Aung, Malene M. Kristensen, Neelam Hassanali, Gonçalo R. Abecasis, John C. Chambers, Fan Zhang, Paul Elliott, Anthony H. Barnett, Fumihiko Takeuchi, Jaspal S. Kooner, M. Ann Kelly, Ananda R. Wickremasinghe, Tien Yin Wong, Wei-Yen Lim, Latonya F. Been, Dharambir K. Sanghera, Samuel Liju, Sudhir Kowlessur, Kerrin S. Small, Yik Ying Teo, Andrew P. Morris, Debashish Das, Viswanathan Mohan, Antigone S. Dimas, Philippe M. Frossard, Jianjun Liu, Chen Suo, Abdul Basit, Tazeen H. Jafar
Publikováno v:
Nature genetics. 43(10)
We carried out a genome-wide association study of type-2 diabetes (T2D) in individuals of South Asian ancestry. Our discovery set included 5,561 individuals with T2D (cases) and 14,458 controls drawn from studies in London, Pakistan and Singapore. We
Autor:
Anthony H. Barnett, M. Ann Kelly, A. Samad Shera, Abdul Basit, J. Paul O'Hare, Simon D. Rees, M. Zafar Iqbal Hydrie, Sudhesh Kumar
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 9, p e24710 (2011)
PLoS ONE, Vol 6, Iss 9, p e24710 (2011)
Background: The Meta-Analysis of Glucose and Insulin related traits Consortium (MAGIC) recently identified 16 loci robustly\ud associated with fasting glucose, some of which were also associated with type 2 diabetes. The purpose of our study was to\u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d816477ab54bf65d2e58fa2e6e25229a
http://wrap.warwick.ac.uk/38319/1/WRAP_Kumar_journal.pone.0024710.pdf
http://wrap.warwick.ac.uk/38319/1/WRAP_Kumar_journal.pone.0024710.pdf
Autor:
Simon D. Rees, Srikanth Bellary, Anthony H. Barnett, Sudhesh Kumar, M. Ann Kelly, J. Paul O'Hare, Abigail C Britten
Publikováno v:
BMC Medical Genetics, Vol 9, Iss 1, p 8 (2008)
BMC Medical Genetics
BMC Medical Genetics
Background Recent studies have implicated variants of the transcription factor 7-like 2 (TCF7L2) gene in genetic susceptibility to type 2 diabetes mellitus in several different populations. The aim of this study was to determine whether variants of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb25a3b875d61a948f7da95a0ec4f763
https://publications.aston.ac.uk/id/eprint/24076/1/Common_variants_of_the_TCF7L2_gene_are_associated_with_increased_risk_of_type_2_diabetes_mellitus.pdf
https://publications.aston.ac.uk/id/eprint/24076/1/Common_variants_of_the_TCF7L2_gene_are_associated_with_increased_risk_of_type_2_diabetes_mellitus.pdf
Autor:
Charles E. Larsen, George S. Eisenbarth, Alberto Pugliese, Chester A. Alper, M. Ann Kelly, Zaheed Husain, Zuheir L. Awdeh
Publikováno v:
Journal of autoimmunity. 30(4)
HLA-DQB1 is widely considered to be the major histocompatibility complex (MHC) susceptibility gene for type 1 diabetes (T1D). However, since inheritance of the gene in T1D is recessive, the presence of the protective HLA-DQB1*0602 allele with normal
Autor:
David A. Hafler, Gavin J. McDonald, David A. Francis, Cari DeLoa, Philip L. De Jager, Jorge R. Oksenberg, Arti Tandon, Scott A. Fruhan, Kristin G. Ardlie, David Reich, Robin R. Lincoln, Stephen L. Hauser, Odile Bera, M. Ann Kelly, Omar Khan, Gilbert Semana, Bruce A.C. Cree, Philippe Cabre, Nick Patterson, Alicja Waliszewska
Publikováno v:
Nature genetics. 37(10)
Multiple sclerosis is a common disease with proven heritability, but, despite large-scale attempts, no underlying risk genes have been identified. Traditional linkage scans have so far identified only one risk haplotype for multiple sclerosis (at HLA